@PFaridi

Laboratory Head @Hudson Institute & @ Monash University, Cancer Immunology, Immunopeptidomics, Proteomics, Childhood Cancer, DIPG.

 Melbourne, Victoria
Joined April 2013
  • Tweets1.4K
  • Following1.6K
  • Followers957
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I'm excited to share that our latest research, "Sensitive neoantigen discovery by real-time mutanome-guided immunopeptidomics," has just been published in Nature Communications! nature.com/articles/s41467-0…

Sensitive neoantigen discovery by real-time mutanome-guided immunopeptidomics

Nature Communications - Mass spectrometry facilitates the scalable identification of cancer-specific HLA-bound peptides; however, the clinical identification of targets remains challenging. Here,...

nature.com
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Team IMF are attending the Brain Cancer Symposium in Banff, Canada. An important meet and greet to foster collaboration between scientists and many charities and to ensure that we are aware of the latest research out there in DMG/DIPG.
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Cryptic but critical: non-canonical antigens in cancer immunotherapy dlvr.it/TLR9tl #immunology
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Just a little goes a long way. Please consider supporting Daniel Walker who is putting so much of himself into this campaign. All donations matched! So a little can go a long way! 😊 chuffed.org/project/ironman-…

Ironman for Impact: Racing to End Childhood Brain Cancer

After a recent health scare, I made a decision — I wasn’t going to waste another minute of this life. I needed to do something meaningful, something extreme, something that could drive real change....

chuffed.org
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Congratulations to the @PFaridi Lab, and the team @Hudson_Research for introducing SAPrim 2.0 - now suitable for analysis of soluble HLA complexes in plasma! Automated mid-throughput identification of >4,000 peptides from 500 µL plasma #MagReSyn frontiersin.org/journals/imm…

Frontiers | SAPrIm 2.0: a semi-automated protocol for mid-throughput soluble HLA immunopeptidomics

Human leukocyte antigen (HLA) molecules are pivotal in guiding human adaptive immune responses through their presentation of peptide ligands, collectively kn...

frontiersin.org
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The Brain Tumor Institute is seeking a talented #ClinicalResearchCoordinator with strong soft skills #HealthcareCareers #ResearchJobs #ClinicalResearch #MedicalResearch Learn more:shorturl.at/c0kO3
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Pouya Faridi retweeted
Jing Yang@Yang_J_lab12 Dec 2024
Very excited to share our Perspective @Nature on how can proteomics help us to live long and prosper🖖#πHuB rdcu.be/d3flE
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Pouya Faridi retweeted
Guomics@guomics25 Nov 2024
On Nov 15, at the Greater Bay Area Science Forum 2024 Sub-Forum, Prof. Ruedi Aebersold presented “The π-HuB project: Measuring, understanding and predicting the properties of life,” showcasing how multi-omics and AI transform precision medicine. #proteomics
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Pouya Faridi retweeted
Guomics@guomics12 Dec 2024
🚀π-HuB: The Proteomic Navigator of the Human Body A groundbreaking initiative to map the human proteome with unprecedented scale and precision. Read our perspective in Nature: nature.com/articles/s41586-0…
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latest paper from the lab describing crystal structure of the human LAG-3-HLA-II complex, in collaboration with @Immutep @MonashUni @SciImmunology @arc_gov_au @Jamie_Rossjohn science.org/doi/10.1126/scii…

Crystal structure of the human LAG-3–HLA-DR1–peptide complex

The structural basis of how the immune checkpoint molecule LAG-3 binds peptide HLA-II is resolved.

science.org
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Hello world! After my lab has been operating in "stealth mode" for 1.5 years, I am excited to announce that we finally have a website: huttenhainlab.com By the way I'm also hiring and looking for a postdoc with proteomics experience: postdocs.stanford.edu/prospe… #TeamMassSpec

Huttenhain Lab | Home

The Huttenhain Lab at Stanford University studies cellular signaling networks to uncover how cells decode extracellular cues into dynamic physiologic responses.

huttenhainlab.com
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New paper describing SAM-DNMT3A, a tool we developed for rapid induction of global genome wide DNA methylation. nature.com/articles/s41467-0…

SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as...

Nature Communications - DNA methylation is an epigenetic mark that plays a critical role in many biological processes. Here, we describe the development of SAM-DNMT3A a tool for induction of genome...

nature.com
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🎺💛I'm delighted to share our latest paper: Machine learning-enhanced immunopeptidomics applied to T-cell epitope discovery for COVID-19 vaccines. Great collaborative effort. Congrats to all 👏 nature.com/articles/s41467-0… @juhussin @mlaval6 @YaleIBIO @HippHupo @hupo_org

Machine learning-enhanced immunopeptidomics applied to T-cell epitope discovery for COVID-19...

Nature Communications - The identification of T cell epitopes is a critical step in understanding the immune response to infection and in designing vaccine based approaches. Here the authors...

nature.com
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Update! We outline AIVE, an AI method for volume EM data. We show the benefits of AIVE for reconstructing your FIB-SEM data, reveal some fascinating cell biology, and define intrusions as a new form of mitochondrial contact. biorxiv.org/content/10.1101/… Muscle mito nanotunnels 1/3🧵
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Delighted to share our paper on the NeoDisc pipeline, developed by the super-talented @FlorianHuber_. NeoDisc is an ‘end-to-end’ clinical antigen discovery pipeline, integrating genomics, transcriptomics and immunopeptidomics nature.com/articles/s41587-0… @HippHupo

A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer...

Nature Biotechnology - The neoantigen discovery pipeline NeoDisc incorporates mass spectrometry immunopeptidomics data.

nature.com
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New low in peer review! Perspective article rejected from a top journal after rev #1 submitted entirely AI review. They focused on limitations in the methodology, results, and data, none of which are present/applicable for perspective piece. Thankfully EIC sorted it after appeal.
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Mai Tran's 1st authored study, alongside co-authors, has been published in @jbiolchem. Her findings detailed T cell receptor recognition of spliced peptides bound to HLA-DQ8. @MonashBDI @RossjohnLab jbc.org/article/S0021-9258(2…

A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by...

Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease that has a strong HLA association, where a number of self-epitopes have been implicated in disease pathogenesis. Human pancreatic...

jbc.org
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Congrats @ETandori and @Jamie_Rossjohn on your stories piece published in Cell on your pioneering work on accessible science.
Cell Press@CellPressNews14 Jul 2024
"Advancing Accessible Science for Low Vision and Diverse Needs Communities" A Stories piece by @MonashBDI Erica Tandori (@ETandori) and Jamie Rossjohn (@Jamie_Rossjohn) Read more in @CellCellPress: cell.com/cell/fulltext/S0092…
Dr. Erica Tandori and Professor Jamie Rossjohn began the Monash Sensory Science Exhibition program in 2018 at Monash University, Australia. Erica (left) holds a T cell sculpture, made of paper-mache and wool; Jamie (right) holds a paper-mache rotavirus model.

ALT Dr. Erica Tandori and Professor Jamie Rossjohn began the Monash Sensory Science Exhibition program in 2018 at Monash University, Australia. Erica (left) holds a T cell sculpture, made of paper-mache and wool; Jamie (right) holds a paper-mache rotavirus model.

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Update that the #VitanzaLab at @seattlechildren research institute is expanding! Thrilled to invite applications for a postdoc position focused on pediatric CNS tumor microenvironment/cellular therapy. Experience a plus. Kindness & collaboration a must. VitanzaLab.org
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I couldn’t be happier that my #MRI #brain scan last Friday showed no evidence of recurrence of my #glioblastoma! It’s now 13.5 months since my seizure in Poland when it showed up. I cannot thank the entire neuro-oncology team enough for looking after me & supporting me so well including A/Prof Michael Back who went through the scans with me. Thanks also to expert #neuroradiologist Dr Jamie Drummond for interpreting the scans and the North Shore Radiology team. I am so fortunate to have such a fabulous caring team looking after me so well especially my wonderful wife Katie & family, friends & colleagues. A #cancer journey is incredibly difficult for patients and their families and just as I continue to rely on my neuro-oncology clinical team for their expert guidance, I strongly encourage all brain cancer patients to continue consulting their own medical teams. @NthSydHealth @SydneyLHD @Sydney_Uni
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