🎉 The Guomics team (@guomics ) led by Prof. Tiannan Guo at Westlake University, together with collaborators, reported ProteinTalks, an operational virtual cell model based on perturbation proteomics that learns how cancer cells respond to drug treatment over time. Published in @Nature 👉 go.nature.com/4cwn4Sg ✨ ProteinTalks introduces a new approach to virtual cell modeling by using time-resolved perturbation proteomics as dynamic supervision and explicitly learning how cellular states evolve over time. This model provides an alternative methodological framework for virtual modeling. #WestlakeUniversity #WestlakeResearch #ProteinTalks #VirtualCell #AIforScience

Latest research from the Tiannan Guo Lab at Westlake University School of Medicine, published in Nature: The team has created an anatomically resolved human proteome atlas, quantifying 13,609 proteins across 58 major tissue types and 25 carcinomas. The study features: 🧬 A spatial proteome map covering fetal, adult, adjacent non-tumor, and tumor tissues 🧬 Tissue-specific protein signatures that refine human proteome annotation 🧬 Systematic characterization of cancer-associated protein changes across multiple tumor types 🧬 Tumor-specific protein features with implications for cancer biology and therapeutic target discovery 🧬 An open-access database, ProteinTalks (db.prottalks.com), to enable proteome exploration and support drug discovery research #WestlakeUniversity #Proteomics #Nature #CancerResearch

🚨 Hot off the press in Cell! Aging isn’t just about wrinkles—it’s molecular! 🧬 A team from Prof. Tiannan Guo’s Lab（@guomics )at Westlake University School of Medicine has mapped how protein restriction (PR) reshapes the aging process across 41 mouse tissues. Their study reveals how tweaking protein intake can modulate aging-related proteins, epigenomic states, and even phosphorylation patterns—with some surprising sex-specific effects! 💪 Could your diet be the key to healthier aging? Read more in Cell👉cell.com/cell/fulltext/S0092… #WestlakeUniversity #WhyWestlake #Protein #aging @CellPressNews