Alexander Opitz lab at the Dept of BioMed Engineering (@UMNBME), University of Minnesota (@UMNews). Research on noninvasive neuromodulation. #TMS #TDCS #TACS

Minneapolis, MN
Joined January 2018
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Replying to @Opitz_Lab
@Opitz_Lab Kicking off the double session on #tACS at #Brainstim2025 in room 501. Join us!
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International Brain Stimulation Conference starts with @Opitz_Lab talk in Kobe Japan
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#UMNproud to receive a $4 million grant to advance transcranial magnetic stimulation. The project is co-led by @Opitz_Lab & aims to develop innovative technologies that could revolutionize treatment for psychiatric disorders. cse.umn.edu/bme/news/alexand…
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We are delighted to announce that Walter Paulus is the recipient of the 2025 International Brain Stimulation Award. Join us at #BrainStimConf Feb 23-26, 2025, Kobe, Japan, where Dr. Paulus will deliver a plenary lecture. poster/symposia deadline 27 Sept. elsevier.com/events/conferen…
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Congrats Ivan! Second lab alumni who is starting their own independent position this year!
Excited to share that I will start as an Assistant Professor of Psychiatry and Behav Sciences at Northwestern University this fall! My lab will do closed-loop brain stimulation and imaging. I look forward to doing cool science together with brilliant colleagues @NUFeinbergMed.
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Congratulations to Dr. Sangjun Lee (Mentor: Dr. Alex Opitz) who received the 2024-2025 #MnDRIVE Neuromodulation Research Fellowship for his project titled, "A novel method for modulation of cognitive functions using traveling wave transcranial alternating current stimulation".
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Please consider applying if you are interested in joining a team focused on adapting and innovating neurotherapeutics for youth Research Fellow - Psychology & Psychiatry jobs.mayoclinic.org/job/roch…
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5/n Synaptic connections affect the entrainment of the postsynaptic neuron with excitatory synapses enhancing neural entrainment
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4/n These de-entrainment and re-entrainment effects are frequency-specific. Furthermore, phase-locking depends also on the natural firing rate of the neurons, with higher firing rates resulting in higher phase-locking values.
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3/n At e-fields of <0.3 V/m tACS de-entrains the neurons, while at higher intensities it re-entrains. Consistent with our previous work (Wischnewski et al., nat commun, 2024) we see that the tACS induced entrainment happens with a phase shift.
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2/n We connected 800 two-compartment pyramidal neurons and 200 fast-spiking interneurons in a 3D volume and investigated the effects of tACS entrainment. Neuron models were structured to mimic the orientation of cortical neurons, and the network contains endogenous oscillations
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CSE researchers showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior. This could lead to new therapies for brain disorders. Read more at z.umn.edu/BrainStimulation @Opitz_Lab @UMNBME @UMNResearch @UMNews @NIH
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Check out our new paper from the lab!
Check out our new publication in @natcomms w/ @Opitz_Lab & @_janzimmermann_ where we show that neural phase precession can be induced by transcranial alternating current stimulation. #tACS #neuroscience #brainstimulation #science doi.org/10.1038/s41467-024-4…
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Very proud of your success! Well deserved!
I am so excited to share that I will be joining the @univgroningen as an assistant professor at the department of Experimental Psychology! Looking forward to meeting new colleagues and doing cool science!
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Great work by Nipun Perera (@nipunWD), as well as all the others, @IvanAlekseichuk, @SShirinpour, @MilesWischnews1, and our collaborators in NY, Gary Linn, Kurt Masiello, Brent Butler, @RussBEneuro, Charles Schroeder, and Arnaud Falchier!
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Our findings hopefully provide insights to TMS-evoked potential research in human using non-invasive #EEG recordings, as well as clinical research using EEG-guided #TMStherapy. 5/5
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These location- and intensity-dependent TMS effects cannot be explained by auditory or somatosensory co-stimulation, as demonstrated by a series of control conditions, including imitation of the TMS click, auditory masking, and peripheral somatosensory stimulation. 4/5
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By exploring the effects of different #TMS coil positions and increasing dose, we found a spatially specific sigmoidal dose-response curve in the TMS-evoked N50 potential. 3/5
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#TMS is #FDA approved for treating various brain disorders. But a lack of intracranial recordings has limited our understanding of TMS-induced neural responses. We tested the effect of TMS-evoked on LFPs by systematically increasing dose and changing location in two NHP. 2/5
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