@OWeinerLab
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Molecular logic of complex cell behaviors. Orion Weiner's lab @UCSF. Account run by lab members. #CellMigration #CellPolarity #Mechanics #OptoTools
San Francisco, CA
Joined February 2021
- Tweets141
- Following186
- Followers1.2K
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We made it to the cover 🤩 !
Our August cover image shows the localization of the WAVE complex (solid colors) and cell edge (dotted lines) of a migrating neutrophil-like HL-60 cell over time. From Pipathsouk, @OWeinerLab et al. (bit.ly/3v117Sq).
Read JCB August Issue: bit.ly/3f8p0m1
Weiner Lab retweeted
👇Take a look at my new @preLights post!
"Rac and Rho team up! Long-distance mechanochemical coordination for migration". Highlighting amazing @biorxiv_cellbio #preprint from lab of @OWeinerLab @HerveTurlier and lead author @Henry_de_belly
prelights.biologists.com/hig…
Weiner Lab retweeted
Henry De Belly's elegant work on front-rear coupling during cell migration is out in bioRxiv! Being a part of this work has been a blast. biorxiv.org/content/10.1101/…
Weiner Lab retweeted
Hello everyone, excited to share our preprint: biorxiv.org/content/10.1101/…
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Everyday, cells like this crawl through your body to protect you. While we know that their front 🔴 and back 🔵 polarity programs work together, how exactly do these two processes communicate? Lets chat!
✨Check out the lab's latest bioRxiv ✨
We explore how cells use long-range mechanochemical feedback to establish and maintain polarity during cell migration!
Hello everyone, excited to share our preprint: biorxiv.org/content/10.1101/…
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Everyday, cells like this crawl through your body to protect you. While we know that their front 🔴 and back 🔵 polarity programs work together, how exactly do these two processes communicate? Lets chat!
✨Pre-print time!✨
Excited to share Kirstin Meyer’s latest work showing how Yap charge patterning mediates transcriptional co-condensate formation! Fantastic collab with @BoHuangLab, Kiersten Ruff, & @ShuLab2010 🤩
biorxiv.org/content/10.1101/…
Weiner Lab retweeted
Happy to share the review Orion & I wrote for Current Opinion in Cell Biology ! @OWeinerLab
authors.elsevier.com/a/1jPA2…
Weiner Lab retweeted
Online now: Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming dlvr.it/T9C9cz
We are thrilled to see Evelyn's paper on neutrophil swarming out in @Dev_Cell!! Congrats to all authors on this beautiful story! 🎉
Check out the 🎆 thread below ⤵️
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✨Pre-print alert!! ✨
Check out Muziyue’s incredible thesis work ➡️ “The WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation”
Super excited to share my thesis work!
doi:biorxiv.org/content/10.1101/…
We found how cells manage to build the extremely flat and thin membrane protrusions with the WAVE complex, that organizes into a linear polymer-like structure at the tips of lamellipodia.
Weiner Lab retweeted
We @SXS_biophysics wrote an insight article on the brilliant work by @tlngy, @strickland_ev, and @OWeinerLab! Combining a classical Percoll assay with CRISPR screening, they reveal how neutrophils use water to migrate and the involvement of PI3K and NHE1. Check it out!
An influx of water molecules can help immune cells called neutrophils to move to where they are needed in the body. elifesciences.org/articles/1…
ALT wiggling spiral pathways on a black background
Weiner Lab retweeted
Our paper on PM abundance as a regulator for myeloid function is out at SI science.org/doi/10.1126/scii…! I would like to thank my mentors Morgan Huse, Orion Weiner, and Jason Cyster and my labmates in @huselab The Morgan Huse Laboratory, @OWeinerLab, and Cyster labs.
Weiner Lab retweeted
‼️ Abstract deadline for BACS 2024 is this Friday April 12 ‼️
We highly encourage trainees at *all levels* to submit an abstract for a talk or poster. Come share your research with the awesome cytoskeleton community in the Bay Area!
🎉 Super excited to announce that registration is now open for the 2024 Bay Area Cytoskeleton Symposium on May 13 at UC Berkeley! 🎉 Keynotes from Eva Nogales & @itsthewoolab, and trainee talks from selected abstracts!
Register now! tinyurl.com/BACS2024
Weiner Lab retweeted
🎉 Super excited to announce that registration is now open for the 2024 Bay Area Cytoskeleton Symposium on May 13 at UC Berkeley! 🎉 Keynotes from Eva Nogales & @itsthewoolab, and trainee talks from selected abstracts!
Register now! tinyurl.com/BACS2024
Weiner Lab retweeted
So hyped to see this great story by @DengkeMa lab being finally out!! This paper is full of fascinating data and I highly recommend a read:
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin science.org/doi/full/10.1126…
Weiner Lab retweeted
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin | Science Advances science.org/doi/10.1126/scia…
Weiner Lab retweeted
My dear friend/collaborator Shannon is starting her lab at Stanford in a couple of months and she is looking to hire a postdoc to work with her on the mechanics of mitosis: biophysics-jobs.careerwebsit…
I cannot recommend Shannon enough, her lab is going to be super awesome!
Meet your new 2024 candidate at the Weiner lab CVRI happy hour! #Ivoted
Excited to share our paper on YAP dynamics and cell fate control! We reveal a concentration-dependent and temporal communication code for YAP that enables cells to choose between different downstream programs. Check it out!
nature.com/articles/s41467-0…
This work is a great collaborative effort with the @HernanGGarcia and @BugajLab labs
We are spinning in circles with excitement to see @JasonPTown fabulous work out @PLOSBiology ⤵️
.@JasonPTown & @OWeinerLab use spatially-defined #optogenetic control of a leading edge organizer to explore how #neutrophil-like cells balance “decisiveness” (needed to polarize in one direction) with flexibility (to respond to new cues) #PLOSBiology plos.io/3ZAldnx
