Interventional Brain Medicine

University of British Columbia
Joined August 2014
Join us in congratulating @UBC_Psychiatry's Clinical Assoc. Prof Dr. Vijay Seethapathy appointment as @CPA_APC president for the 2025-2026 term! 📢 lnkd.in/dwNNbPYw
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The @NinetLab & @UBC_Psychiatry are pleased to announce a 3-day CPD-accredited course providing psychiatrists with practical & theoretical training in repetitive transcranial magnetic stimulation (rTMS) bit.ly/NINET-rTMS
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How does ECT compare to TMS in depression? 2.5x higher response rates (38% vs 15%) in crossover study of 138 patients (each pt got both treatments): pubmed.ncbi.nlm.nih.gov/3804… #ECT (but not #TMS) is particularly effective for psychotic #depression. #psychiatry #mentalhealth
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Our latest article addresses: 1) does TMS propagate better to sgACC in positive or anticorrelated PFC FC targets, per interleaved TMS/fMRI? 2) any difference MDD vs. Healthy? 3) does TMS-evoked sgACC fMRI correlate with mood/affect? See sciencedirect.com/science/ar…🧠🧲⚡️
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Child health in Gaza - @TheLancet -1% of children killed -Largest cohort of child amputees in modern history -20% moderate and 4% severe acute malnutrition - >17000 children are without one or both parents @Lisa_Doughten @save_children @Oxfam @UNRWA
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This study inspired a lot of contention, so I'll add a few points: 1. CBT takes many forms. For benzo withdrawal, it resembles CBT for panic and involves physical exercises (eg, progressive muscle relaxation). 2. CBT #therapy and medication both cause physical changes in the brain and body. If prescription meds were the only pathway to physiologic healing, our ancestors would not have survived long. 3. No medication has good efficacy data for #benzo WD, while CBT has at least 4 randomized controlled trials.
What works best for #benzo withdrawal? #CBT has the best evidence, and in this study it worked for people who used both benzos and opioids even when delivered as #teletherapy pubmed.ncbi.nlm.nih.gov/3773… Patient guide: amzn.to/3zQYzPi #therapy #anxiety
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A group of #academics has brought a federal antitrust lawsuit against six academic publishers alleging they engaged in a conspiracy that allows them to sustain huge profits at the expense of scientific progress. Long overdue. forbes.com/sites/michaeltnie…
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Viewpoint discusses why it is important for psychiatry residency programs to continue to prioritize the training of psychiatrist-scientists. ja.ma/4884mgp
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Kyeong Jae Lee et al. develops tiny implantable magnetic coil (3.5mm) successfully modulates brain activity in rats! Study shows 88% increase in motor responses with controlled heating, opening new possibilities for precise, focal brain stimulation. brainstimjrnl.com/article/S1…
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This meta-analysis shows that bright light therapy is an effective adjunctive treatment for nonseasonal depressive disorders. ja.ma/4gQcbeh
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Orthosomnia is "obsessive pursuit of optimal sleep fueled by an unhealthy fixation on data from sleep-tracking devices... leading to counterproductive behaviors that paradoxically impair sleep." Proposed 2017, new study: pubmed.ncbi.nlm.nih.gov/3930… #insomnia #psychiatry #neurology
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Out @NatureNeuro: Network localization of brain stim targets for PTSD. TLDR: Lesions connected to this circuit REDUCE risk of PTSD in Vets. Also tested with fMRI and TMS. Free link: rdcu.be/dUVTY With @foxmdphd @NoahSPhilipMD @davidcarreon @AArulpragasam @MoreyLab
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Nationwide Danish study shows that continuing electroconvulsive therapy as maintenance treatment is associated with a better outcome and lower treatment costs in patients with severe psychiatric illness. ja.ma/4dfzF9I
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A white paper summarizing a recent Focused Ultrasound in Psychiatry Symposium (FUS PULSE) is now available. In June, over 70 experts attended the educational workshop hosted by @Sunnybrook to explore the use of focused ultrasound for treating psychiatric disorders and develop a roadmap for advancing the technology. “This field is burgeoning quite quickly,” said Suzanne LeBlang, MD, the Foundation’s director of clinical relationships. “The breadth of ongoing preclinical and clinical research is remarkable, including trials for depression, obsessive-compulsive disorder, anxiety, and even addiction.” ow.ly/uWsE50ToKR7
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🌟 IMH SHOWCASE: Meet Dr. Nick Ainsworth (@hi_doctornick), a Marshall Fellow and Geriatric Psychiatrist! Read about his work advancing treatment for late-life depression: bit.ly/IMH-showcase @UBC_Psychiatry
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We’re grateful to ⁦@FUSFoundation⁩ for helping us host a workshop charting the course of focused ultrasound in psychiatry, a rapidly growing field. Read our white paper here and looking forward to the second edition in 2026! ⁦@BenDavidson__⁩ fusfoundation.org/posts/focu…
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NINET Lab retweeted
Happy to share that our work applying precision mapping to individuals with depression sampled longitudinally over an extended period has been published this week in @nature. Brief recap of the main findings and their potential implications below. nature.com/articles/s41586-0…
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#Antidepressant responses in #depression plateau at higher dose in network analysis of 160 trials: pubmed.ncbi.nlm.nih.gov/3890… Exceptions? tricyclics, reboxetine in this study. Also, in earlier studies, MAOIs, venlafazine, desvenlafaxine, vortioxetine. #psychiatry
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Theta-burst stim (TBS) is used to treat depression, but how does it work? I dug into this question in my research yr with @DrCoreyKeller @ACPaulk, now out in @NatureComms, finding that TBS can produce plasticity-like changes in just minutes of stim. nature.com/articles/s41467-0…
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