A collaborative group for early- and mid-career faculty who study nuclear receptors. Advancing science and career development.
Joined December 2020
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- Following27
- Followers135
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NR IMPACT retweeted
For #WomensHistoryMonth, @zmadak is honoring JES Associate Editor (bit.ly/39Ubs9D), @Prof_Riggins, for her knowledge and mentorship. @womensday #IWD2023 #InternationalWomensDay
NR IMPACT retweeted
For #WomensHistoryMonth, @emiliampinto is honoring @Katja_K_Vassi, who is serving on our Annual Meeting Steering Committee, Endocrine Cancers SIG, #JCEM Editorial Board, for her passion and dedication to adrenocortical disorders. @womensday #IWD2023 #InternationalWomensDay (1/2)
NR IMPACT retweeted
For #WomensHistoryMonth, @mjsikora is celebrating both @Prof_Riggins and @zmadak for their years of colleagueship. He admires their selfless contributions of time, energy, and support for trainees and faculty. @womensday #IWD2023 #InternationalWomensDay
NR IMPACT retweeted
So excited to share the newest #pollocklab manuscript in @EndoSocJournals - this was my first (mini)review and super exciting to write on advances in prodrugs of #estrogenreceptor alongside my undergraduate student Hannah. academic.oup.com/jes/article…
NR IMPACT retweeted
Fantastic job by @ZheqiL and others in the lab. Thanks @mjsikora @JCarrollLab for help. Maybe @NR_IMPACT can take this on for other receptors, other tumor types? In the meantime pls provide #feedback 🙏 #bcsm – at Fox Chapel, PA
Please RT: ER/E2/breast cancer. We are seeking #crowdsourced datasets and opinions. We curated 136 published datasets, processed with one pipeline and made a browser to visualize E2-induced expression and ER binding. Feel free to try it out estrogene.org/ 🧵
NR IMPACT retweeted
Excited to share a new @biorxivpreprint from the lab! In this study, we show that RXRα ligands activate transcription of Nurr1-RXRα heterodimers through a mechanism distinct from classical pharmacological #nuclearreceptor activation. doi.org/10.1101/2022.11.08.5… 🧵 @NR_IMPACT
NR IMPACT retweeted
What a cool story from @NR_IMPACT member Doug Kojetin and colleagues dissecting Nurr1-RXRα regulation. NMR, transcriptional control, small molecules...what more can you ask for 😁
Molecular basis of ligand-dependent Nurr1-RXRα activation biorxiv.org/content/10.1101/…
#NuclearReceptors #NMR #TR-FRET
Estrogene is an outstanding new resource to query the current state of knowledge of the ER-alpha transcriptome and cistrome in breast cancer models - fair warning that you might lose a day looking for your favorite genes!
We're intrigued by the idea of expanding this though...
Fantastic job by @ZheqiL and others in the lab. Thanks @mjsikora @JCarrollLab for help. Maybe @NR_IMPACT can take this on for other receptors, other tumor types? In the meantime pls provide #feedback 🙏 #bcsm
NR IMPACT retweeted
Please consider applying for our Summer Undergraduate Research Experience in Toxicology at the University of Illinois. This program is designed for under-represented undergraduate students that are interested in Toxicology. Due date Feb 15, 2023.
vetmed.illinois.edu/suretox/
NR IMPACT retweeted
Our next step towards a clinical-grade #CAMKK2 inhibitor. Team effort led by @dhdrewry.
@Dr_CaMKkinase @MetSigLab @anwarmedc @Chenchu48450284 @AwadDom @donaldmcdonnell
#dark_kinases
#randomactofkinases
SGC-CAMKK2-1: A chemical probe for CAMKK2 biorxiv.org/content/10.1101/…
#sgcunc; @thesgconline; @dhdrewry
NR IMPACT retweeted
See @LindseySTrevino discuss her experiences as a Latina in #endocrinology, and how important the support she received by peers in @TheEndoSociety's FLARE program has been to her career:
bit.ly/3D5Lv7L
#HispanicHeritageMonth
NR IMPACT is thrilled to welcome 5 new members! These scientists increase IMPACT's collective expertise in metabolism, structural biology and ligand binding, neuropharmacology, and cancer biology.
nrimpact.com/members
Without further ado... 🧵1/7
.@AyeshaShafi14 is at @USUhealthsci. The Shafi Lab is focused on defining mechanisms and biomarkers of therapeutic resistance in patients with advanced prostate cancer (PCa) with the goal to develop better treatment strategies.
usuhs.edu/node/122655
6/7
NR IMPACT retweeted
#HispanicHeritageMonth Featured Member | @LindseySTrevino an Outstanding Abstract Award winner, speaks on her experience as one of the few Latinas during her career, and the support she received from peers in FLARE (bit.ly/2N5iKxV): bit.ly/3T2DqWr
NR IMPACT retweeted
I was a guest on "The Scientist Speaks" podcast from @TheScientistLLC
"What Comes Up Must Go Down: Maintaining Hormone Balance Through RNA Decay"
bit.ly/3CsW9DT
Huge thanks to @NSpahich for the invite and fun chat about my lab's research here at @CUAnschutz @rnabioco
