We elucidate #pediatric #cancer & #metabolism to tackle #childhoodcancer. #translation regulation. Raphael’s tweets _RJM. Join our fight @KispiZuerich @UZH_en!
Zurich, Switzerland
Joined October 2023
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Morscher Lab - #PediatricCancerMetabolism retweeted
Our Review on “Aneuploidy as a driver of human cancer” is out in Nature Genetics. Check it out! 🎉
The Ben-David lab wishes everyone Shana Tova — may the new year be much better than the ending one, bringing peace and stability to all! 🙏
nature.com/articles/s41588-0…
Morscher Lab - #PediatricCancerMetabolism retweeted
We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (biorxiv.org/content/10.1101/…)!
Morscher Lab - #PediatricCancerMetabolism retweeted
Very proud of our first paper @MorscherLab. It was great working hand-in-hand with the @debocklab to understand how metabolism controls muscle stem cell fate 🤝💪
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Morscher Lab - #PediatricCancerMetabolism retweeted
Embracing Cancer Complexity: Hallmarks of Systemic Disease, now out in Cell!
authors.elsevier.com/c/1iqgj…
Morscher Lab - #PediatricCancerMetabolism retweeted
Do young and old protein molecules have the same probability to be degraded?
@ErikMcshane, @SelbachLab and colleagues investigated this question and found that for some proteins the proabrbility of degradation decreases as they age.
Morscher Lab - #PediatricCancerMetabolism retweeted
Our admiration to @CarlKoschmann, Pediatric Neuro-Oncologist at Chad Carr Cancer Center, @umichmedicine. From clinic to research to free rock climbing classes, he supports kids with cancer from all angles. Watch his inspiring story from @NBCNews: buff.ly/3OGRBAK
Morscher Lab - #PediatricCancerMetabolism retweeted
Great review about the reprogramming of metabolism and its role during metastasis..focus is on lipids
nature.com/articles/s43018-0…
Morscher Lab - #PediatricCancerMetabolism retweeted
Structural basis for human mitochondrial tRNA maturation biorxiv.org/content/10.1101/…
Morscher Lab - #PediatricCancerMetabolism retweeted
Woohoo 🥳 Our paper on mitoribosomal synthetic lethality in MYC-driven neuroblastoma has got into the CDDpress Monthly Readers' Choice collection. So grateful to have our work presented among such influential papers 🥹 @FNUSA_ICRC @BiologieUstav
nature.com/articles/s41419-0…
Morscher Lab - #PediatricCancerMetabolism retweeted
🚨New paper alert! Our latest work has been published in @MolecularCell today, check it out here! 👇
Online Now: Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma dlvr.it/T0wFq8
Morscher Lab - #PediatricCancerMetabolism retweeted
Officially out in @NatMetabolism📖: our latest work showing changes how cells acquire amino acids during early development. Congratulations to Pavlina! rdcu.be/du2Z7 @SKI_CellBiology
Morscher Lab - #PediatricCancerMetabolism retweeted
Functional-metabolic coupling in distinct renal cell types coordinates organ-wide physiology and delays premature ageing
nature.com/articles/s41467-0…
Morscher Lab - #PediatricCancerMetabolism retweeted
We are looking for a talented postdoctoral fellow with strong in vivo experience to work with us on #formate #metabolism in context of #Metastasis. Please RT 🙏
@LIH_Luxembourg @ERC_Research
careers.lih.lu/jobs/detail/p…
Morscher Lab - #PediatricCancerMetabolism retweeted
Extremely thrilled to announce the publication of our joint paper with Moshe Oren and his group @WeizmannScience on the role of p53 in immuno-metabolic cross talk between breast cancer cells and adipocytes.
@MetaboholicsLab @DKFZ
Online now at PNAS. pnas.org/doi/10.1073/pnas.23…
Morscher Lab - #PediatricCancerMetabolism retweeted
Nature research paper: Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes go.nature.com/4awbaVw
Morscher Lab - #PediatricCancerMetabolism retweeted
ARE METABOLIC ENZYMES ON CHROMATIN?
Yes, they are ⤵️!
We optimized a chromatin enrichment protocol to improve the extraction of chromatin-bound proteins (chromatome) and applied it to > 140 samples, including cancer cell lines and healthy epithelia from 10 different tissues. 🧵
Morscher Lab - #PediatricCancerMetabolism retweeted
My Postdoctoral project just got published in @ScienceAdvances. Thanks to @vavatin and all my colleagues @neuroenergeticslab @TU_muenchen & @UniFAU 🫶
science.org/doi/10.1126/sc…
Check out our main results in the 🧵 below.
xitter.cf/vavatin/status/1735332…
@ScienceAdvances published our paper in which we asked: "Where does all the sugar go in the brain?" ...it's less the size of the brain, than slow chemical signaling, 4 main findings below 🧵
doi.org/10.1126/sciadv.adi76…
#ScienceAdvancesResearch
funding: Starting Grant @ERC_Research
Morscher Lab - #PediatricCancerMetabolism retweeted
embl.org/jobs/position/HD024… Postdoc opportunities in our lab in Heidelberg.Join us to develop leading-edge computational methods for spatial omics technologies in health and disease. See also SpatialData biorxiv.org/content/10.1101/… for recent work. Get in touch if interested. Please RT.
Morscher Lab - #PediatricCancerMetabolism retweeted
Very nice work where SLC6A14 and SLC25A15 are identified as major cytoplasmic and mitochondrial serine transporters in cancer cells
nature.com/articles/s42255-0…
Morscher Lab - #PediatricCancerMetabolism retweeted
Time for celebration 🥳🥳🥳 – at Marseille, France
🌟 Exciting news in #PediatricOncology ! 🌟 South-ROCK, a Lyon-Marseille research center of Excellence, has received 6M from @Institut_cancer to improve the care and prevention of pediatric cancers. Stay tuned for crucial advancements! 🚀 #SouthROCK
👉 crcm-marseille.fr/en/news/cr…