@MolSwitches

Bringing you news about state-of-the-art Molecular Switches, Machines and what lies in-between

Joined January 2016
  • Tweets1.8K
  • Following360
  • Followers1.4K
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Molecular Switches retweeted
J. Am. Chem. Soc.@J_A_C_S4 Nov 2025
Photoswitchable RNA Degraders for Spatiotemporal Activation of Host-Directed Antivirals in Mammalian Cells | Journal of the American Chemical Society @ETH_DCHAB @ETH_en pubs.acs.org/doi/10.1021/jac…

Photoswitchable RNA Degraders for Spatiotemporal Activation of Host-Directed Antivirals in Mammal...

Abstract. Strategies to develop broad-spectrum antivirals are highly sought after. A promising modern approach includes recruitment of host proteins as a m

pubs.acs.org
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Molecular Switches retweeted
Biosensors MDPI@Biosensors_MDPI13 Nov 2025
📣Call for Reading: #Communication Rational Design of High-Performance Hemithioindigo-Based Photoswitchable AIE Photosensitizer and Enabling Reversible Control Singlet Oxygen Generation by Junjie Wang, et al. #AIE #photosensitizer #PDT #biosensors #mdpi #openaccess
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Molecular Switches retweeted
Stefano Crespi@stefano_crespi1 Dec 2025
Check out our new 🔥 paper on the triply gated isomerization of the phosphorous analogue of indirubin💡! Acid‐ and Nucleophile‐Gated Photoisomerization of Phosphaindirubin - Wal - Angewandte Chemie International Edition - Wiley Online Library share.google/BFvZS3oMbedmvTB…

Acid‐ and Nucleophile‐Gated Photoisomerization of Phosphaindirubin

Triply gated isomerization: In polar solvents, a phosphorus-containing indirubin photoswitch undergoes visible-light-driven Z→E isomerization only when protonated, and reverts thermally via nucleop...

onlinelibrary.wiley.com
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Molecular Switches retweeted
Luca Laraia@laraialab27 Nov 2025
Delighted to have collaborated with the @DirkTrauner lab on the development and characterisation of #photoswitchable #cholesterol derivatives, now out in @J_A_C_S! Led by Michael Zott, with excellent work from @Laura_dta from our group @ChemistryDtu pubs.acs.org/doi/full/10.102…

Development of Photoswitchable Cholesterol Derivatives through Side Chain Replacement

Abstract. Cholesterol is ubiquitous in biology, shaping membrane properties and serving as a biosynthetic precursor for essential signaling molecules and h

pubs.acs.org
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Molecular Switches retweeted
Chemistry News
@ChemistryNews1 Dec 2025
Ultrafast spectroscopic signatures for off-to-on photoswitchable species in a green-to-red photoconvertible fluorescent protein pubs.rsc.org/en/Content/Arti…

Ultrafast spectroscopic signatures for off-to-on photoswitchable species in a green-to-red photoc...

Photoconvertible fluorescent proteins (pcFPs) have greatly advanced life sciences and cellular imaging with sub-diffraction resolution. A subset of Kaede-l

pubs.rsc.org
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Molecular Switches retweeted
BioPhotonics@TheBioPhotonics1 Dec 2025
A new, photoswitchable molecule, developed at UNIST, demonstrates repeatable, reversible assembly-disassembly capabilities when irradiated with different wavelengths of light. #BioPhotonics #Wavelengths #Light Read more here: photonics.com/Articles/Light…

Light-Driven Molecular Approach Provides Phototherapeutic Benefit

photonics.com
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Molecular Switches retweeted
SmartCell_Unisi@smartcell_unisi2 Dec 2025
Photomodulation of Vesicle Dynamics Using Fluorescent Photoswitchable Amphiphiles - now published in Journal of Materials Chemistry B pubs.rsc.org/en/content/arti…

Photomodulation of vesicle dynamics using fluorescent photoswitchable amphiphiles

Modulating membrane permeability and morphology remains a central challenge in the design of responsive colloidal and self-assembled systems. Here, we pres

pubs.rsc.org
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🚀 New preprint alert! Happy to share our latest work now on ChemRxiv: 🔗 chemrxiv.org/engage/chemrxiv… Huge congratulations to @diptipravaSAHO7, Akanksha and Anshuman. Grateful for the continued support from @tvmiiser and @ANRFIndia. #photoswitchable architectures, #chirality

Influence of Distance and Angle Between Pliers and Rotors on Helicity Switching: Exploring the...

Bisporphyrin tweezers can be rendered chiral either by introducing a stereogenic unit or by complexing with a chiral guest via axial coordination. To investigate this mode of chiral induction, four...

chemrxiv.org
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Molecular Switches retweeted
Chemistry News
@ChemistryNews10 Dec 2025
Photoswitchable latent monomers enable on‑demand metathesis nature.com/articles/s41557-0…
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Molecular Switches retweeted
J. Am. Chem. Soc.@J_A_C_S11 Dec 2025
Switching and Quantifying the Single-Molecule Mechanochemical Reactivity of Four-Membered Carbocycle Mechanophores within a Single, Photoswitchable Polymer Strand | Journal of the American Chemical Society @StanfordUChem @Stanford @DukeU pubs.acs.org/doi/10.1021/jac…

Switching and Quantifying the Single-Molecule Mechanochemical Reactivity of Four-Membered Carbocy...

Abstract. The reactivity of four-membered carbocycle mechanophores, such as cyclobutane (CB), cyclobutene (CBE), and benzocyclobutene (BCB), has been explo

pubs.acs.org
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Turn up the Vitamin D Receptor─Not the Calcium! Photoswitchable Vitamin D Agonists for Psoriasis | ACS Central Science pubs.acs.org/doi/10.1021/acs…

Turn up the Vitamin D ReceptorNot the Calcium! Photoswitchable Vitamin D Agonists for Psoriasis

Photopharmacology is an emerging interdisciplinary field at the interface of pharmacology and photochemistry that takes advantage of molecular transducers

pubs.acs.org
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🚨New research from @JuliaKalow + @kalowlab: “Donor–Acceptor Stenhouse Adducts as Intrinsically Photoswitchable Dynamic Covalent Bonds” Read more in @J_A_C_S 👉 pubs.acs.org/doi/full/10.102…
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Molecular Switches retweeted
Angewandte Chemie@angew_chem24 Oct 2025
A Photoswitchable HaloTag for Spatiotemporal Control of Fluorescence in Living Cells (Claire Deo and co-workers) #openaccess 🔓 onlinelibrary.wiley.com/doi/…

A Photoswitchable HaloTag for Spatiotemporal Control of Fluorescence in Living Cells

Photoswitchable fluorophores are critical for advanced bioimaging. Here, we develop a photoswitchable self-labeling HaloTag that can reversibly modulate the emission of a bound fluorogenic dye via a...

onlinelibrary.wiley.com
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Molecular Switches retweeted
Harry Anderson Group@HLAGroupOx24 Oct 2025
Design principles for photoswitchable fluorescent dyads - out now in @ChemicalScience. We present a series of switchable fluorophores and rationalise their behaviour with a photophysical/photochemical model. pubs.rsc.org/en/content/arti…
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Molecular Switches retweeted
Judy Wu@JudyWuChem18 Sep 2025
Now in @J_A_C_S. Sharing Francisco’s new work on modulating the thermal isomerization mechanisms of photoswitching azoarenes. pubs.acs.org/doi/full/10.102…

Triplet Spin Delocalization and Temperature Dependence for Adiabatic and Non-Adiabatic Z–E Isomer...

Abstract. Photoswitching molecules like the azoarenes have myriad potential applications, ranging from energy storage to targeted drug delivery. Upon irrad

pubs.acs.org
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Molecular Switches retweeted
Light Lab@The_LightLab9 Oct 2025
HOT from @ChemicalScience; Introduction of a cationic phosphorous on dimethyldihydropyrene photoswitches was hard but led to cool switching with 740 nm light in water. Both ways, vis light switch @mlm7996 @Chand55118Sayan @SamyadebM @iiserkol @ANRFIndia pubs.rsc.org/en/content/arti…

Installation of cationic phosphorus on dimethyldihydropyrene photoswitches: expanding the atomic...

We have synthesized for the first time a small library of negative photochromic dimethyldihydropyrene phosphonium salts (DHPPs) that can be activated by re

pubs.rsc.org
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Molecular Switches retweeted
MOF Papers@MOF_papers14 Oct 2025
Photoswitching Conduction in Framework Materials advanced.onlinelibrary.wiley…

Photoswitching Conduction in Framework Materials

This mini-review summarizes recent advances in state-of-the-art proton and electron conduction in framework materials that can be remotely and reversibly switched on and off by light. It discusses...

advanced.onlinelibrary.wiley.com
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#CoverFeature Orthogonal Photoswitching in Nematic #LiquidCrystal|s (Bart Jan Ravoo and co-workers) ChemEurJ 57/2025 doi.org/10.1002/chem.2025018… • onlinelibrary.wiley.com/doi/…
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Molecular Switches retweeted
Chemistry News
@ChemistryNews23 Oct 2025
Tuning the Photocaged Spiropyran Photoswitch with a Sterically Hindered Adamantane Group: Releasing the Stable Merocyanine pubs.rsc.org/en/Content/Arti…

Tuning the photocaged spiropyran photoswitch with a sterically hindered adamantane group: releasing...

Molecular photoswitches isomerize between two or more forms by exposure to light or by thermal processes, accompanied by color changes. Spiropyran (SP) der

pubs.rsc.org
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Molecular Switches retweeted
Jake Greenfield@JakeyLG8 Sep 2025
📢New perspective on light responsive imine-based systems out now in @ChemicalScience with @GalliumWu💡🚨🔦 This is part of the 2025 Leading Investigators Collection, Thank you to the reviewers for input 🙏 #hot #photoswitch #imine imineswitch.com doi.org/10.1039/D5SC05210F
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