Bacterial signaling, c-di-GMP, c-di-AMP, protein domains NCBI's Comp. Bio. Branch, COG database, J. Bacteriology

Bethesda, MD
Joined May 2016
Чёрт, вся моя молодость прошла под эту музыку (позывные Русской службы Би-Би-Си) youtube.com/watch?v=z1088E6E…
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Michael Galperin retweeted
I can't believe what I've just watched. A Jewish lawyer wearing a Star of David was arrested after the police alleged the symbol had "antagonised" pro-Palestine protesters. He was handcuffed and detained by police for almost TEN hours. DISGUSTING! Shame on you @metpoliceuk.
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Michael Galperin retweeted
Very happy to share that a large part of my thesis work is out today: B. subtilis uses the second messenger c-di-AMP to modulate its turgor pressure in response to the state of its cell envelope.  nature.com/articles/s41564-0…
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Michael Galperin retweeted
We cracked the mystery: Pteridines are the natural ligands of CutA, a widespread protein in nature @HHU_de @CoE_CMFI I started this project 8y ago. We showed that it's of PII signaling family, but it's role remained unknown coz we didn't know what it bind biorxiv.org/content/10.1101/…
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Michael Galperin retweeted
Congratulations to my former postdoc supervisor, Prof. George Salmond. A well-deserved recognition! @MicrobioSoc microbiologysociety.org/news…
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I know one thing. Zelenskyy would’ve received a hero’s welcome from these guys, and sent home with enough ammo to go all the way to Moscow.
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Michael Galperin retweeted
TfpY is a conserved accessory protein found in type IV pili (T4P)-expressing bacteria. While T4P are often phage receptors, research in #JBacteriology suggests TfpY does not mediate phage defense, but instead facilitates efficient pilus assembly/function. asm.social/2gA
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Michael Galperin retweeted
Formate-specific chemoreceptors and their evolution in bacteria. Very grateful to be part of this multidisciplinary and international research team @KrellLaboratory @Eli_Monteagudo @zhulinlab @gavirius. @BlastMeetings @CSICdivulga @SEMicrobiologia pnas.org/doi/10.1073/pnas.24…
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Michael Galperin retweeted
Read more about our discovery in the thread by lead author @TanaWein 👇 xitter.cf/TanaWein/status/188468…
Very happy our paper on CARD domains in gasdermin anti-phage defense systems is now published in @Nature 🥳 Thanks to all the people involved especially the Kranzusch lab and @SorekLab nature.com/articles/s41586-0…
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Michael Galperin retweeted
Our paper out @CellCellPress: Structure-guided discovery of viral proteins that inhibit host immunity Congrats @ErezTzvi, Azita Leavitt, @amitai_gil, our collaborators @ Kranzusch lab, and coauthors A 🧵 1/10 cell.com/cell/abstract/S0092…
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Michael Galperin retweeted
Dr. Beile Gao from South China Sea Institute of Oceanology, Chinese Academy of Sciences, presents new work on Campylobacter jejuni! Her talk on how a novel tetrameric PilZ protein stabilizes the stator ring in the complex flagellar motor is a must-see! 🧬🌊 #BLASTMeeting2025
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Michael Galperin retweeted
We are honored to welcome Dr. Ann Stock of @RutgersU as the keynote speaker at #BLASTMeeting2025! 🌟With decades of pioneering research in bacterial signal transduction, Dr. Stock will discuss "Two-Component System Design Principles." @J_Bacteriology @plosbiology
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A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Michael Galperin retweeted
Biden promised 500,000 EV charging stations. 2 years later, only 7 have been built… When politicians spend your money, they don’t have an incentive to spend it carefully. So they fail, over and over:
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