@Michohl1980

Scientist interested in Structural Microbiology, climber, father. PDRA: @thelowlab @imperialcollege, SNF Fellow: @ThomasMeierLab, PDRA/PhD: @seegerlab @UZH_en

 London
Joined September 2018
  • Tweets86
  • Following148
  • Followers78
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Please have a look at the new paper of the Low lab @thelowlab. The second take on the Tad pilus system, providing the structural basis of the bidirectional pilus processing by CpaF. Great collaboration with Tung Le @Tung_BK_Le and @EmmaJBanks. nature.com/articles/s41467-0…

Bidirectional pilus processing in the Tad pilus system motor CpaF

Nature Communications - The ATPase CpaF from C. crescentus powers pilus dynamics in the bacterial Tad pilus system. Cryo-EM and light microscopy characterisation of CpaF uncovers a mechanism for...

nature.com
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Sub-3 A resolution protein structure determination by single-particle cryo-EM at 100 keV biorxiv.org/cgi/content/shor… #biorxiv_biophys
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Wonderful work by @Michohl1980 and @EmmaJBanks probing how the bacterial Tad pilus system motor powers both pilus assembly and retraction. Thank you to the @Tung_BK_Le lab for the fantastic collaboration.. 👏 nature.com/articles/s41467-0…

Bidirectional pilus processing in the Tad pilus system motor CpaF

Nature Communications - The ATPase CpaF from C. crescentus powers pilus dynamics in the bacterial Tad pilus system. Cryo-EM and light microscopy characterisation of CpaF uncovers a mechanism for...

nature.com
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Excited to share a new preprint of the lab! Using native SV2A and cryo-EM we provide the structural basis for tetanus toxin entry into central neurons and reveal the binding mode of the anti-seizure drug Levetiracetam used in the treatment of epilepsy.   biorxiv.org/content/10.1101/…
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We're looking for a postdoc and an RA to join us @ucl! Interested in how the #malaria parasite adapts its cytoskeleton for disease transmission? Join our @wellcometrust funded project and use #insitu #CryoET to study parasites! DM or email any questions. Links in the comments.
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📢1x PDRA & 1 x PhD position available 📢 @ImperialInfect, @imperialcollege Building minimal gut microbiome models using 3D printing & fluidics 🖨🦠🤖 PhD deadline : 12 th of January 2024 (home fees) PDRA deadline: 30 th of January 2024 Apply 👇 mpl-group.github.io/join.htm…
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Have a look at the second paper about Vipp1 from the Harry Low's lab.
Harry Low’s Lab@thelowlab27 Sep 2023
The missing piece in the bacterial #ESCRT-III story.. #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😎😵‍💫 Wonderful collaboration with @Colom_D @RouxLab… 1/2 biorxiv.org/content/10.1101/…
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Excited to share our first exploration of the pilus-forming Tad secretion system in bacteria.. here showing the assembly mechanism of a secretin-pilotin complex.. And congratulations to brilliant @Matteo_tassina for his relentless heroics in the lab 👏 nature.com/articles/s41467-0…
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Michael Hohl retweeted
Seeger Lab@seegerlab30 Jan 2023
An MFS transporter that extracts lipids from membrane with the help of a lipoprotein?!?🤩 Check out our paper on the fascinating duo of Rv1410 and LprG on @biorxivpreprint! biorxiv.org/content/10.1101/…
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Michael Hohl retweeted
BBC News (UK)
@BBCNews17 Jan 2023
How to drive in snow and icy weather bbc.in/3Wbr2Ve

How to drive in snow and icy weather

If you have to drive during wintry weather, here is how to prepare your car, and what to carry with you.

bbc.com
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We have funding for a postdoc (3 years) or PhD student (4 years) on an exciting project linking structural biology, microbiology, biochemistry and biophysics. We look for a candidate who has an excellent educational background in one of these fields...
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«Beiji», «Bieni» oder doch «Immi»? Wo in der #Schweiz die #Biene 🐝 welchen Namen trägt, zeigt der neue Schweizerdeutsche Sprachatlas @sdatsbern in der schweizerischen Bienenzeitung: bienenzeitung.ch/rettet-die-…. @snf_ch #Bienen #Bees #dialekt #savethebees

Rettet die Immen!? | Schweizerische Bienen-Zeitung

«Save the Bees!» oder «Rettet die Bienen!» ist ein Ausruf geworden, der auf den Klimawandel aufmerksam macht und den sich nicht nur Imkerinnen und Imker auf ...

bienenzeitung.ch
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WE ARE HIRING! Are you excited about membrane proteins, membrane biology and cryo-EM? Opening for a fully funded 4-years PhD position in my lab at VIB in Brussels @structbiolbxl. Please RT.     jobs.vib.be/j/53349/phd-posi…    #cryoEM #MembraneProteins #Biochemistry @VIBLifeSciences
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Michael Hohl retweeted
Seeger Lab@seegerlab28 Nov 2022
Proud to see our DMS paper out in @nchembio after going through a productive review process🥳EfrCD's drug efflux activity profile determined for >1400 single variants. Identified single mutations that convert the exporter into a drug-specific ABC importer! nature.com/articles/s41589-0…
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Los gatos viven en otra realidad 😙
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Following the installation of ALERT, we are very grateful to Brahmal Vasudevan and Shanthi Kandiah for giving @imperialcollege the opportunity to be the setting for a striking new artwork by Antony Gormley, one of the UK’s foremost living artists. imperial.ac.uk/news/239911/a…
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"Knowledge is our best common good." Happy 80th birthday to 2017 chemistry laureate Jacques Dubochet! #NobelPrize

Jacques Dubochet on knowledge

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!!We’re still looking to fill this postdoctoral job opening!! 🕺💃Interested in understanding the role and mechanism of ESCRT-III-like membrane remodelling proteins in bacteria?.. then come join us! #Cryoem #CryoET Please retweet! imperial.ac.uk/jobs/descript……
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How the research team of Philippe Plattet and @seegerlab is achieving high viral neutralisation and low resistance using #sybodies in their #NRP78 project: bit.ly/3l8hkmo @snsf_ch @marcelsalathe
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!!Postdoctoral job opening!! 🕺💃Interested in understanding the role and mechanism of ESCRT-III-like membrane remodelling proteins in bacteria?.. then come join us! #Cryoem #CryoET Please retweet! imperial.ac.uk/jobs/descript…
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