@seegerlab

Lab of Prof. Markus A. Seeger, @UZH_en, tweets by group members; great admirers of membrane proteins, nanobodies, sybodies, structural biology and microbiology

 Zurich, Switzerland
seegerlab.org/
Joined May 2019
  • Tweets335
  • Following300
  • Followers986
72Media
Learn how a mycobacterial MFS transporter extracts hydrophobic triacylglycerides from the membrane and channels then into a periplasmic lipoprotein🤩Our story on the fascinating duo of Rv1410 and LprG is out now in @NatureComms 🥂🙌 nature.com/articles/s41467-0… #mycobacteria #CryoEM
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🥳Congrats to Sujani on successfully defending her PhD thesis! We are thrilled to celebrate your success and couldn't be prouder of all you've accomplished thanks to your determination, diligence and passion💪🥳
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I‘m happy to share our work on laser flash melting to overcome preferred orientation in cryo-EM samples! 🥳❄️🔬 More infos on the underlying mechanism of particle redistribution and the use for preferred orientation issues in the 🧵 or here: biorxiv.org/content/10.1101/…
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Mega start of the #nordinfect symposium in Kiel with the keynote talk from @seegerlab ! Beautiful venue at the Leuchtturm der Wissenschaften ⚓️🛳️
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If you are interested in a joined effort towards building a synthetic cell (including -of course- membrane transporters), have a look at this post: nature.com/naturecareers/job…

12 PhD/Post doc positions for the design and engineering of synthetic cells - Netherlands (NL)

12 PhD/Post doc positions for the design and engineering of synthetic cells

nature.com
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Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. @befcorreia @sokrypton biorxiv.org/content/10.1101/…
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It is a wrap 🙌🏽 ! Thank you so much to academic and industry speakers, tutors and participants who attended the EMBO practical course mPEPC3 in EMBL Hamburg/ CSSB. We had 8 days of lectures, practicals and networking on the membrane protein field 📚🦠🔬 👏🏽 to our sponsors!
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Day five of the EMBO practical course “ Membrane protein expression, purification and characterisation 3 (mPEPC3)” in EMBL HH/CCSB. Markus Seeger, on Saturday morning , introducing us to Sybodies libraries to target membrane proteins for downstream applications💥🔎 #EMBOPEPC
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Man-made hinges date back to 1600 BC. ⭐️postdoc Benedikt Kuhn et al. now show that elevator-like #solutecarriers had them long before 🤩 to control conformational space + function! Great collab w Julian Langer lab and @seegerlab. Out in @NatureComms doi.org/10.1038/s41467-024-5…
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Potential future treatments by targeting SLC transporter regulatory hinges to revive activity, revealed using a #Sybody enabler. Congrats to the Geertsma & Seeger labs for great work in @Nature. #StandWithUkraine #biotechnology #pharmacology #antibody nature.com/articles/s41467-0…

Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA

Nature Communications - Elevator transporters, like SLC23 proteins, transport solutes by a mechanism involving a reorientation of two rigid domains. Here, the authors show that linkers connecting...

nature.com
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I am looking for a postdoc to work on structural biology of chlorophyll biosynthesis. Reach out if you are fascinated by #cryoEM, #photosynthesis and #cyanobacteria and join us in the dynamic city of Osnabrück! uni-osnabrueck.de/universita… @UniOsnabrueck @dfg_public
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We are looking for a PhD student to work on Structural Biology of Membrane Transporters at Instituto Biofisika in the Bilbao area (shorturl.at/hVudg) Apply if you are enthusiastic about working at the leading edge of structural biology #PhDposition #cryoEM #MembraneProteins
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🥳Congrats to Jennifer on successfully defending her PhD thesis! Your hardwork, perseverance and resilience led to the success of your project! We're very proud of all your achievements🥰 A special shout-out to winning the grid freezing game against Markus🤣
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And many thanks for @CPaulino_ for being in her PhD committee and coming all the way to Zurich from Heidelberg!
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Seeger Lab retweeted
FGCZ@FGCZ_EN17 Jun 2024
We had a great inaugural 'Students on Stage at the FGCZ' event last week! Congratulations to @SchLuk_ for winning the best presentation award from @renuo Stay tuned for the second edition...
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Exciting news! I'm looking for talented individuals to join my soon-to-be-launched Emmy Noether group supported by @dfg_public and @UniOsnabrueck! Reach out if you're passionate about #cryoEM and #photosynthesis! bit.ly/ChlorophyllPhD bit.ly/ChlorophyllPostdoc #ScienceJobs
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Enjoy this giant artwork on Irchel Campus: It was painted by French-Swiss artist SAYPE using eco-friendly paint. The ephemeral artwork is in support of @SOSMedSuisse which was awarded the @rightlivelihood Award, also known as Alternative Nobel Prize. @saype_artiste @uzh_rlc
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Our lab is looking for a part-time (50% FTE) Research Assistant to help out with lab management and cloning. Looking for someone with a MSc degree and good DNA cloning experience. message or email me if interested
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Alright everybody, what will undoubtedly forever be the lab's strangest discovery is now out in Nature. It's a protein that evolved to self-assemble into a Sierpinski fractal. nature.com/articles/s41586-0… 1/n
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Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs | bioRxiv biorxiv.org/content/10.1101/…
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Mark's tour-de-force work shows that the ABC transporter BacA from Mycobacterium mediates unprecedented bi-directional transport of cobalamin. Great team effort with Solène and @chancie_t (Chancie) nature.com/articles/s41467-0…
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