Multinational team focused on curing cancer with cell therapy & immuno-engineering. Product safety, efficacy, reproducibility, and affordability are key.

Cleveland, OH
Joined January 2022
MelenhorstLab retweeted
👏 Congrats to Prof. @carlhjune on receiving the @AbarcaPrize! His pioneering work in CAR-T therapy has transformed cancer treatment. During my time in his lab, I had the chance to experience his inspiring vision and trust, for which I am deeply grateful. abarcaprize.com/award-winner…
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Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress cell.com/cell/fulltext/S0092… tweetorial👇
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MelenhorstLab retweeted
Super cool to see our work highlighted by @ACIR_org If you haven’t had a chance to check it out yet this is a great summary!
New insights into nivolumab-induced immunoediting bit.ly/403lMIZ  @TylerAlban1  @xrtGenomics  @GeneCollector
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MelenhorstLab retweeted
Super excited to share the final publication of Spectra, fruit of the wonderful collaboration between @russell_kunes and @science_wallet, a gene program factorization program that I hope will help many interpret and bring insight from their single-cell data -->
Supervised discovery of interpretable gene programs from single-cell data go.nature.com/460weRo
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We are looking for doctors who are interested in Hematology and Oncology Hospitalist positions @ClevelandClinic practicematch.com/CareerCent… – at Solon, OH
MelenhorstLab retweeted
Bioicons.com Here is an alternative to BioRender that is TRULY FREE and actively maintained. Over 1500 vectorized images sorted by license type (all creative commons or MIT). Fully editable icons and soon they will launch an Inkscape library.
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MelenhorstLab retweeted
Excited to share TEMPOmap, our new spatiotemporal transcriptomics method that integrates metabolic labeling with 3D in situ sequencing to simultaneously profile the age and location of individual RNA molecules led by @JingyiRen Haowen Zhou and @huzengHZ biorxiv.org/content/10.1101/…
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Cleveland Clinic is selected as the leading healthcare system in a new initiative to accelerate collaboration and innovation in quantum computing. Developed by @ConnectedDMV, this hub leverages our partnership with @IBMResearch to advance medicine. cle.clinic/3UKK6dz
MelenhorstLab retweeted
Applications open for a pediatric oncology physician scientist. Pediatric neuro-oncology focused clinical practice and laboratory program. Contact below to apply. Great opportunity to join a top cancer program. practicematch.com/physicians…
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CAR-T Day in Lille France has been a wonderful meeting. Highly recommended! ⁦@MelenhorstLab⁩ ⁦@PaulosLab⁩ ⁦@KlebanoffLab⁩ ⁦@EvanWeberPhD⁩ #SumanMitra #JimKochenderfer #RobertaDiBlasi
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MelenhorstLab retweeted
Honored and humbled to be inducted to NAI. Believe in technology innovation for science, humanity, inclusion and patients! @AcadofInventors #NAI2022
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Collaborators at @UPennIBI and @YaleBME unveiled molecular mechanisms ⚙️ that may inform strategies to boost specific T cell function to maintain long-term remission in acute lymphoblastic #leukemia patients. @MelenhorstLab @camara_pg @RongFan8 📎 bit.ly/3xxOymd
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MelenhorstLab retweeted
Impressive phase 1 trial results testing a Claudin18.2-specific CAR in patients with R/R #GImalignancies. Favorable toxicity profile and correlation between T cell persistence and antitumor efficacy. @NatureMedicine
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MelenhorstLab retweeted
Thanks @sitcancer and @ReilleyMD for inviting me! I will discuss the work from my lab @YaleSEAS @YaleMed in collaboration with @MelenhorstLab @camara_pg @carlhjune @GruppSteve of @Penn on single cell profiling of CAR T infusion products to predict long term therapeutic response.
Join @RongFan8 (Yale University) and @ReilleyMD (University of Virginia) for the April 27 SITC-@theNCI Computational IO webinar, New Technologies for Clinical Decision Making and Research: Computational Science in Immuno-Oncology. Register for free at sitcancer.org/CompIO
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Watching the #AACR22 session on the effect of sex on tumor response? ICYMI in @CD_AACR: Myeloid-derived suppressor cell subsets drive #glioblastoma growth in a sex-specific manner @d_bayik @JustinLathia @caseccc aacrjournals.org/cancerdisco…
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MelenhorstLab retweeted
Beautiful work! PDAC, CAF, IL-6 signaling, therapeutic resistance... It seems all the dots are finally connected now.
Now online in @CD_AACR: Identification of Functional #Heterogeneity of Carcinoma-Associated #Fibroblasts with Distinct IL-6 Mediated Therapy Resistance in #PancreaticCancer @rkalluriMDPhD @KalluriLab @MDAndersonNews aacrjournals.org/cancerdisco…
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Major milestone in the history of @ClevelandClinic !! Opening of the new hospital in London
Cleveland Clinic London sees its first patients at 33 Grosvenor Place today. It's @ClevelandClinic's first hospital in Europe, expanding our global healthcare system. Read more: cle.clinic/3iJqswM
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Happy #MatchDay2022 everyone! Enjoy this comedy gold from Dr. G. – at Cutler, FL
Congratulating the newly matched med students
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Looking forward to a working weekend at the UF ReMission Summit! Great to see friends in person and connect with great foundations such as @sontagfdn @theABTA @NBTStweets
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