T cell specialists lab! @EmorySurgery @WinshipAtEmory
Atlanta, GA
Joined May 2011
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Paulos Lab retweeted
Check out Dr. @GuillermoORang1's new Cancer Research paper. We show that not all stem-like memory CD8 T cells are equal...
Progressively enhancing stemness of adoptively transferred T cells with PI3Kδ blockade improves metabolism and anti-tumor immunity aacrjournals-org.proxy.libra…
Check out Dr. @GuillermoORang1's new Cancer Research paper. We show that not all stem-like memory CD8 T cells are equal...
Progressively enhancing stemness of adoptively transferred T cells with PI3Kδ blockade improves metabolism and anti-tumor immunity aacrjournals-org.proxy.libra…
Newest preprint paper by our team (@LesinskiLab & @pauloslab) in biRxiv! @WinshipAtEmory @sitcancer
Clinically relevant orthotopic pancreatic cancer models for adoptive T cell therapy biorxiv.org/content/10.1101/…
Paulos Lab retweeted
Excited to announce that this manuscript is officially out in the latest issue of JCI! Thanks again to all the coauthors and of course to my postdoc mentor Don Gibbons for his continual support! The model figure from these studies:
Targeting autotaxin enhances immune checkpoint blockade response: buff.ly/44AzwcD
@jessica_konen @MDAndersonNews
#Immunology #Oncology
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Friends and colleagues, our talented and hardworking technician, Soundharya needs your help! Please help us fundraise for her and her family in her time of need!
Share/donate! Any bit will help!
Fundraiser for Soundharya Kumaresan gofund.me/f46bc35c
☀️A must read by our MSTP student @GuillermoORang1! The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner. biorxiv.org/content/10.1101/…
⭐️A must read!!! Congrats to @LesinskiLab & team for stellar work in novel immunotherapy to impact #PancreaticCancer. Just out in @JCI_insight: insight.jci.org/articles/vie…. @sitcancer @ImmunologyAAI @WinshipAtEmory
Our paper is out! Dual IL6/CTLA4 blockade in #PancreaticCancer so many collaborators over many years. @WinshipAtEmory @BwareRedHair @phillipsmaggiej @Chrystal_Paulos @hknochelmann @greeneEMnM @CarsonLabOSU @brobinsonGIpath @TMaceLab @cameron_herting @anruggieri @BasselElRayesMD
We @PaulosLab honored to be #JITCTop10 for this coolio B cell ACT CD8 T cell paper. ;)
Countdown to 2023: #JITCTop10 - B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity bit.ly/332sJis @Aubrey_Smith04 @PaulosLab
CD40-activated B cells to the rescue! jitc.bmj.com/content/10/12/e…
CD40 agonism may circumvent a dysfunctional CD4 compartment to improve PD-1 blockade responsiveness, supporting a novel synergistic immunotherapeutic approach.jitc.bmj.com/content/10/12/e…
Increased numbers of neutrophils and macrophages associated with cancer progression may be risk factors for anaphylaxis. jitc.bmj.com/content/10/12/e…
The best of the best of the best, herein!! Woot @AyanaTRuffin
#BIIW22 #BlackInImmunoRollCall
Hi there! I’m Ayana and I am a postdoc fellow in the @PaulosLab at @WinshipAtEmory . I am currently obsessed with B cells and their best friend CD4 T cells and how we might use both in adoptive cell therapy to treat cancer.
Paulos Lab retweeted
💥Less is more: @MeganMWyatt’s new manuscript in @biorxivpreprint shows metabolically fit CAR T cells can be generated using fewer activation beads in @PaulosLab w/ @LesinskiLab @ImmuneCellsRUs. Props @GuillermoORang1 @hknochelmann @nelson_CD26 @Aubrey_Smith04 @WinshipAtEmory
Augmenting TCR signal strength and ICOS costimulation results in metabolically fit and therapeutically potent human CAR Th17 cell therapy biorxiv.org/cgi/content/shor… #bioRxiv
‘Wolde ye bothe eate your cake, and haue your cake?’
-John Heywood, 1546
Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy pubmed.ncbi.nlm.nih.gov/2432…
Paulos Lab retweeted
The @PaulosLab is VERY thrilled to welcome our #gamechanger postdoc fellow @AyanaTRuffin to @EmoryUniversity @WinshipAtEmory!
Paulos Lab retweeted
… and an essay in the NYT. 7/ nytimes.com/2022/06/20/opini…
Paulos Lab retweeted
#ASCO22 | June 3 | Education Session | Developmental Therapeutics
"Tebentafusp for Uveal Melanoma"
Panel Speaker: Melinda Yushak, MD, MPH
#melsm ➡️ fal.cn/3pawg
