@McKeatingLab

Breathe, it's viral o'clock

 Oxford, England
mckeatinglab.uk
Joined July 2020
  • Tweets134
  • Following100
  • Followers231
8Media
🌟 My last paper w/@maini_lab is out in the wild! 👩‍🔬 Modulating cholesterol esterification has a direct antiviral and T cell boosting effect against SARS-COV-2 w/@McKeatingLab @pacman481 🔮 This may provide a novel therapeutic strategy in the future tinyurl.com/46nx3ezt
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McKeatingLab retweeted
PHD Comics@PHDcomics27 Sep 2023
Final.doc
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This #WorlsHepatitisDay find out more about NDM's contributions towards finding the cure for #hepatitis B virus infections 🦠 Know more about @mckeatinglab's research on hepatitis: mckeatinglab.uk/
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Fantastic work by @GMAGillespie Andrew McMichael and many more about our favourite non-classical HLA molecule! shorturl.at/zDO18 Great to see the appreciation of HLA-E-restricted immune responses against #SARSCoV2 in @SciImmunology
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Liver researchers are well represented @The_MRC fellows symposium: MRC chief executive John Iredale, with fellows Hamish Innes (@UofGlasgow), @WeiYu_Lu (@EdinUni_IRR) @druppygill (@QMUL) @TriantafyllouE_ (@imperialcollege) @alan_xa @alan (@HealthUCL) & me for @BirminghamLiver
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Today, during the Nido2023 conference at Montreux Switzerland, Dr Peter Wing (B24 user from @UniofOxford) & Patrick Philip (Joint PhD student with @eBIC_Diamond , @UniofOxford & @Pirbright_Inst) presented their projects aided by the techniques at B24 diamond.ac.uk/Instruments/Bi…
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McKeatingLab retweeted
Maini Lab UCL@maini_lab5 May 2023
🚨💊Opportunity for drug re-purposing of a cholesterol esterification inhibitor ...that has both direct #antiviral and #Tcell boosting potential in #COVID19 pubmed.ncbi.nlm.nih.gov/3713…

An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity - PubMed

The severity of disease following infection with SARS-CoV-2 is determined by viral replication kinetics and host immunity, with early T cell responses and/or suppression of viraemia driving a...

pubmed.ncbi.nlm.nih.gov
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COVID, COVID, COVID. Congratulations to Dr Peter Wing from @UniofOxford for his illuminating talk! Starving SARS-CoV-2 of oxygen halted its replication in lung epithelial cells, and Peter used soft X-ray tomography to understand how hypoxic mitochondria stave off the virus.
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Circadian cycles orchestrate many functions of the immune system. Find out a bit about how this was discovered and what new research is telling us about circadian immunity in this featuring @McKeatingLab @LM_Ince @jkimmey @gibbs_lab_UoM: nautil.us/immunity-is-a-matt… #sciencesunday

How Circadian Rhythms and Time of Day Control the Immune System

Vaccines, infections, and diseases can all be influenced by our circadian rhythm.

nautil.us
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McKeatingLab retweeted
Zhuang_Lab@XAZhuang8 Feb 2023
Proud to announce our in-person event - Oxford Life Science Association Symposium 2023 at St. Peter’s College on Monday 27th Feb. Please find speakers information and register following the link: olsa.life/2023_Symposium/OLS…
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McKeatingLab retweeted
Arjun Raj
@arjunrajlab5 Feb 2023
I have a feeling that RNA FISH-based transcriptomics will have a side benefit beyond spatial information: much higher accuracy, mostly due to direct detection/lack of PCR-based amplification. I suspect a lot of hand-wringing about batch correction will be a thing of the past.
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We’re pleased to welcome four new members with an extensive range of experience and perspectives to our Board of Directors: Federico (Fede) Pelisch, Jane McKeating, Freddie Quek and Joanne Hackett. Meet them here ⬇️ 1/6 elifesciences.org/inside-eli…
headshots of the four new members of E life's Board of Directors

ALT headshots of the four new members of E life's Board of Directors

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An open letter to @gavi: hepatitis B birth dose vaccine can’t wait Signed by @CDAFound @GlobalHep @HepAus @EndHep2030 @HepBFoundation @MSF_access @PATHtweets #TREATAsia @amfAR @uicc @Hep_Alliance thelancet.com/journals/langa… #nohep #endhep #HBV @GaviSeth
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It’s on fire. (Cartoon for @newscientist ) #Science
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Why do we meet ‘in person’/‘on zoom’ and not ‘in vivo’/‘in silico’?
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McKeatingLab retweeted
Maini Lab UCL@maini_lab13 Apr 2022
❗️Non-peer reviewed preprint❗️ We are excited to share our new preprint lead by our own @natha_schmidt 👩‍🔬 and @pacman481 👨🏻‍🔬from the @McKeatingLab! The ACAT inhibitor Avasimibe has unique direct #antiviral and #Tcell boosting activity in #SARS-CoV-2 biorxiv.org/content/10.1101/…
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McKeatingLab retweeted
Hannah Brown@HBrown08906 Apr 2022
If you’re at @MicrobioSoc today and want to see some exciting new work, head over to @NerdyNic talk this morning to hear about the antiviral that might be about to take the world by storm! @ucdvetmed @UCD_CHAS @UCD_Conway #Antivirals #SARSCoV2 #Virology
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We have a new paper out! In collaboration with @castello_lab and the McKeating lab and @jefflee1103 and @dalia_science made some fascinating discoveries about how the different variants of the virus that causes Covid19 behaves in cells. Short explainer video in plain English here
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"I would do anything for love, but I won't read that"
Rogue Virologist@RVirologist21 Jan 2022
Dammit, we've been scooped by a new Cell paper that completely figured out COVID-19 via a *blood atlas*. There's nothing left to work on; it's clear as day. (If it's confusing for you, the graphical abstract-- boxed in red below-- should completely clear it up.)
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