@McKeatingLab

Breathe, it's viral o'clock

 Oxford, England
mckeatinglab.uk
Joined July 2020
  • Tweets134
  • Following100
  • Followers231
8Media
This account is closed, you'll now find us here : @mckeatinglab.bsky.social
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We have a new identity! MckeatingLab is now on Blue Sky, let's see how it goes...
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Great talk from Peter @hypoxeu highlighting the importance of hypoxia in viral infection
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#PLOSPathogens: An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity dx.plos.org/10.1371/journal.…

An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity

Author summary Cholesterol metabolism is a key element in both viral replication and immune cell signalling. We show that Avasimibe, an inhibitor of the cholesterol esterification enzyme Acyl-CoA:c...

journals.plos.org
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🌟 My last paper w/@maini_lab is out in the wild! 👩‍🔬 Modulating cholesterol esterification has a direct antiviral and T cell boosting effect against SARS-COV-2 w/@McKeatingLab @pacman481 🔮 This may provide a novel therapeutic strategy in the future tinyurl.com/46nx3ezt
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Academy of Medical Sciences elects two NDM researchers as new Fellows ndm.ox.ac.uk/news/academy-of…

Academy of Medical Sciences elects two NDM researchers as new Fellows

The Academy of Medical Sciences has elected two medical scientists from the Nuffield Department of Medicine to its fellowship in 2024.

ndm.ox.ac.uk
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Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus - go.shr.lc/3wLgju8

Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus

microbiologyresearch.org
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Our new review is out! HBV INTERNATIONAL 2023 KOBE MEETING - a report microbiologysociety.org/blog…..

HBV international 2023 Kobe meeting

Jane A McKeating and Peter Revill take us behind the scenes of their latest publication 'Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus' published in...

microbiologysociety.org
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Viruses Finally Reveal Their Complex Social Life quantamagazine.org/viruses-f… via @QuantaMagazine

Viruses Finally Reveal Their Complex Social Life | Quanta Magazine

New research has uncovered a social world of viruses full of cheating, cooperation and other intrigues, suggesting that viruses make sense only as members of a community.

quantamagazine.org
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Oxygen-dependent histone lysine demethylase 4 restricts hepatitis B virus replication - Journal of Biological Chemistry jbc.org/article/S0021-9258(2…

Oxygen-dependent histone lysine demethylase 4 restricts hepatitis B virus replication

Mammalian cells have evolved strategies to regulate gene expression when oxygen is limited. Hypoxia-inducible factors (HIF) are the major transcriptional regulators of host gene expression. We...

jbc.org
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#PLOSPathogens: The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome dx.plos.org/10.1371/journal.…

The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome

Author summary Oxygen levels influence HBV replication and hypoxia inducible factors (HIFs) activate HBV transcription. Long-read sequencing and mapping the HBV transcriptome showed an increased...

journals.plos.org
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Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome biorxiv.org/content/10.1101/…

Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouri...

Pseudouridine (Ψ) is one of the most abundant modifications in cellular RNA. However, its function remains elusive, mainly due to the lack of highly sensitive and accurate detection methods. To...

biorxiv.org
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Out now in iScience, excellent Christmas present : Hypoxia inducible factors inhibit respiratory syncytial virus infectio... sciencedirect.com/science/ar…
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We all recognise this!
Martijn Luijsterburg@luijsterburglab20 Dec 2023
Publish a paper they said, it will be fun they said!
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Congratulations DR Borrmann! As the picture says - YAY!
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First ever UK #HBV has now finished. SO pleased that our very own James Harris got the prize for best talk!
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McKeatingLab retweeted
PHD Comics@PHDcomics27 Sep 2023
Final.doc
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Helene's last paper as a DPhil student! Inhibition of salt inducible kinases reduces rhythmic HIV-1 replication and reactivation from latency pubmed.ncbi.nlm.nih.gov/3752…

Inhibition of salt inducible kinases reduces rhythmic HIV-1 replication and reactivation from...

Human immunodeficiency virus type 1 (HIV-1) causes a major burden on global health, and eradication of latent virus infection is one of the biggest challenges in the field. The circadian clock is an...

pubmed.ncbi.nlm.nih.gov
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This #WorlsHepatitisDay find out more about NDM's contributions towards finding the cure for #hepatitis B virus infections 🦠 Know more about @mckeatinglab's research on hepatitis: mckeatinglab.uk/
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