We develop advanced #opticalmapping and #electricalmapping systems to to pinpoint the exact areas of diseased tissue/cells with abnormal electrical conductivity

United Kingdom
Joined January 2018
A new study shows that inherited arrhythmias like CPVT are not driven by cardiomyocytes (CM) alone. Using hiPSC-derived neuro-cardiac models, the team found dysfunctional sympathetic neurons can trigger #arrhythmia in otherwise healthy CM. #electrophysiology #cardiology #mapping
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One of the simplest ways to record field potentials and ECG in a Langendorff heart preparation. Simply apply microelectrode arrays and ECG electrodes directly to the heart. #CardioTwitter #Electrophysiology #ElectricalMapping #DrugScreening #Cardiotoxicity #iPSC #Heart
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We are excited to announce the successful installation of our optical mapping system in the laboratory of Prof. Nipavan Chiamvimonvat at the University of Arizona. The system is now fully operational and provides high-resolution, synchronized mapping of cardiac AP and Ca signals.
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The first gene-edited miniature pig model of LQT2 is here. By combining ECG telemetry, electrical mapping, and optical mapping, this study delivers a truly translational view of hERG-related arrhythmias in a large-animal heart. Short version: bit.ly/4jaguCV
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In RyR2-R420Q CPVT hearts, subthreshold delayed afterdepolarizations prolonged local repolarization and delayed subsequent activations, increasing ventricular activation dispersion. Optical mapping analyses suggest this mechanism contributes to re-entrant arrhythmia formation.
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Cai et. al. (2025) developed a human engineered heart tissue model to mimic lipotoxic diabetic cardiomyopathy and found that empagliflozin effectively protects cardiomyocytes by reducing mitochondrial damage, endoplasmic reticulum stress, and apoptosis. #cardiotwitter
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Our electrical mapping workflow offers a fast and accessible way to measure epicardial field potentials — ideal for quick assessments in drug testing and disease models. ⚡📷 #activationmap #electrophysiology #Langendorff #drugscreening #cardiotwitter #Cardiology
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Unlock the mysteries of cardiac arrhythmias with our advanced Electrical Mapping System! High precision data acquisition and MEA provide unparalleled insights into electrical activity at the tissue level. Perfect for anti-arrhythmic drug screening and toxicity testing.
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Yu et al. (2025) showed that an Andr-loaded atrial patch prevents POAF by reducing inflammation, oxidative stress, and calcium imbalance. In a rat model, it lowered Afib incidence from 90% to 20% and protected heart cells, highlighting a promising targeted therapy for POAF.
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A new video showcasing our Calcium and Contractility Mapping System on iPSC-CMs. It enables simultaneous, high-res measurement of Ca transients and contractility with advanced mapping features. #cardiomyocyte #singlecell #mapping #calcium #electrophysiology #cardiology #ipsc
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We’re delighted to meet new friends and clients at #BCVS2025. Thank you very much for the great conversations—looking forward to future collaborations in cardiac research. @carmine_3Dheart @HanKimLab @lamc_14 @AHAMeetings @American_Heart #bcvs25
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We are exhibiting at the BCVS in Baltimore. We warmly invite all researchers and colleagues to visit our booth and connect with our team. #BCVS2025 @AHAScience @AHAMeetings @American_Heart #cardiotwitter #electrophysiology #microelectrodearray #opticalmapping
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"Functional assessment of iPSC-CM monolayers using optical mapping." Feel free to reach out for more info. #electrophysiology #cardiology #heart #opticalmapping #cardiacresearch #ipsc #cardiomyocyte #arrhythmia
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…and she is still doing what she does best in 2025.
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