@MachidaLab

Molecular biology lab @NCIResearchCtr, @theNCI investigating DNA repair mechanisms. Views are my own.

 Bethesda, MD
Joined January 2020
  • Tweets136
  • Following146
  • Followers77
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A new database developed by NCI scientists details how 2,675 different compounds affect the growth of #CancerCells. Learn more about this resource for researchers, called CellMinerCDB: NCATS. ccr.cancer.gov/news/article/…

With new database, NCATS data is poised to support development of precision cancer therapies

Data from thousands of compounds and nearly 200 cancer cell lines screened at the National Center for Advancing Translational Sciences are available through a new CellMiner database.

ccr.cancer.gov
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Replying to @theNCI
Welcome to the DTB @NCIResearchCtr !
Replying to @LabSchellenberg @Fusion_Conf
Congrats, Sowmiya! I wish I was there to celebrate together.
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Replying to @LabSchellenberg @MayoClinic @theNCI
Thank you, Matt! Glad that our cart found a new home @MayoClinic – at Minnesota, USA
Replying to @TaishiYonezawa @MayoClinic @theNCI
Thank you, Taishi! – at Minnesota, USA
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Replying to @DrSadhanaJ @MayoClinic @theNCI @IRPatNIH
Thank you, Matt! – at Minnesota, USA
Replying to @MayoClinic @theNCI
Thank you, Jill! – at Minnesota, USA
Replying to @SonikpreetA
Thank you, Sonikpreet! – at Minnesota, USA
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Thank you, Tom! Looking forward to new collaborations with NIH investigators. Yes, we’ll be recruiting soon! – at Minnesota, USA
Replying to @ShanYanLab @MayoClinic @theNCI
Thank you, Shan!
After 13 wonderful years at @MayoClinic, I am moving on to a new adventure. Starting January 2022, I’ll be joining @NCIResearchCtr, @theNCI as a Senior Investigator. – at Minnesota, USA
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Congratulations, Julian! – at Minnesota, USA
Machida Lab retweeted
Shan Yan@ShanYanLab21 Aug 2020
Please RT (1/n): SI “Environmental Health and Genome Integrity” co-edited Cyrus Vaziri @UNC @ShanYanLab is published in @EMMjournal. Contributors include Nobel Laureate Aziz Sancar @UNC.. @EMGSUS @ChancellorGaber @UNCC_CLAS @UNCC_Academics @unccharlotte onlinelibrary.wiley.com/toc/…

Environmental and Molecular Mutagenesis | EMGS Journal | Wiley Online Library

Click on the title to browse this issue

onlinelibrary.wiley.com
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Online Now: Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging dlvr.it/RbHcq3

Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects...

Huang et al. discover the deubiquitinase VCPIP1 is required for SPRTN activation and further demonstrate that SPRTN activation is regulated by two-step post-translational modification, deubiquitina...

cell.com
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Thank you Scott! I really enjoyed the discussion. – at Minnesota, USA
Machida Lab retweeted
Zha Lab@zha_lab12 Jun 2020
I am excited to launch the weekly Social DNAing webinar series on June 18,2020- a virtual meeting room for the genomic instability community. Check it out as cancer.columbia.edu/dna-webi…
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Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease cell.com/molecular-cell/full… – at Minnesota, USA
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Machida Lab retweeted
Cell@CellCellPress11 Jun 2020
In the latest issue! Rad54 promotes an #active mechanism for #homology searching during #homologous #recombination bit.ly/3hgfj4p @DNAcurtain @Columbia
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Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq dlvr.it/RXzVmk

Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and...

We present a method for genome-wide, nucleotide-resolution mapping of DNA single-strand breaks in purified genomic DNA based on capture of 3′-OH ends followed by sequencing (GLOE-Seq). We validate...

cell.com
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BRCA1 Mutational Complementation Induces Synthetic Viability dlvr.it/RY2y3W
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