DNA repair lab at the Mayo Clinic
Joined September 2019
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Schellenberg Lab retweeted
#PhF25 predoc awardee Anh Cong @MayoGradSchool is researching how to protect the heart during #chemotherapy. She's studying the proteins targeted by anthracyclines, which are effective against #cancer but can cause heart issues.
Watch the full interview: phrmafoundation.org/news-eve…
Topobexin is an inhibitor that targets Topoisomerase IIβ's ATPase domain—protecting the heart from anthracycline chemo damage without reducing anticancer power. Read our article about this potentially game-changer in cardio-oncology @natcomms.nature.com rdcu.be/en4ak.
This was an awesome collaborative team effort by scientists from @MayoClinic @mayoclinicbmb @MayoGradSchool @MayoCancerCare @newcastleuni and the faculties of Pharmacy and Medicine at Charles University.
Schellenberg Lab retweeted
Endoxifen is known to be a more potent inhibitor of ER alpha compared to tamoxifen. Based on an unbiased proteomic screen, we identify protein kinase beta as a new endoxifen drug target, resulting in suppression of AKT signaling and apoptosis
pubmed.ncbi.nlm.nih.gov/3811…
Schellenberg Lab retweeted
We are so excited to present “Structural insight and characterization of human Twinkle helicase in mitochondrial disease” in @PNASNews pnas.org/doi/10.1073/pnas.22…
Schellenberg Lab retweeted
Alpha fold definitely has its uses, it’s great starting model, but then there’s oligomerization, conformational change, protein-to-protein interactions. We aren’t out of a job! #structuralbiology
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Today is my first in-person conference talk as a PI! It’s been a great PS36 meeting in San Francisco
Congratulations to our Mayo graduate student Sowmiya Palani and her poster prize at the in-person @Fusion_Conf #DRRSC22
Excited to have a preprint of my labs first paper out. Who says protein preps have to be boring and clear? Add some colour! It’s about more than just how it looks. biorxiv.org/content/10.1101/…
Happy to be part of this really cool project that was made possible by the diverse expertise and collaborative environment at the Mayo Clinic. We are very proud of this! biorxiv.org/content/10.1101/…
Schellenberg Lab retweeted
New PI Lesson #508 - be very clear when providing the title of your seminar. 🤦♂️ #needmoresleep #sicktoddler
Schellenberg Lab retweeted
We are excited to welcome the 2022 Spring Speakers for the Social DNAing Webinar! Let us the Science continue! Thank you for all your supports! More is coming on cancer.columbia.edu/research…
2/4 to block their spouse from joining them in this country? We force this brilliant scientist to choose between family and their research, and they end up leaving for another county, which is a loss for our institution, the State of Minnesota, and the United States. All because
3/4 one person in a position of power decided these #scientists and #engineers were not worthy of being trusted to follow the rules of their visa??? It’s OK, I’m sure their decision had nothing to do with the spouse’s brown skin.
