Faculty @Concordia @biologyatCU in Montréal 🚲 Canada Research Chair T2 Computational Genomics https://xitter.cf/t.co/8MMQbl9VWM

Montréal, Québec
Joined July 2014
🎆I am beyond thrilled to announce that I will be joining @Concordia Biology department as an Associate Professor in the Fall 2024! My Computational Genomics lab will use multi-omics to understand environmental and genetic contributions to human health. 🧬🧑‍💻
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Marie-Julie Favé retweeted
We are delighted to share the latest findings from the lab in Nature! We report mutation-dependent effects of sleep and exercise on clonal hematopoiesis (CH) and its associated atherosclerosis. nature.com/articles/s41586-0…
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Marie-Julie Favé retweeted
Big progress vs cancer, folks. The kind of event curves from randomized trials that we've not seen before for a couple of the most deadly cancers. Congrats to the oncology research community for getting these trial done. #ASCO26, @ASCO
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Marie-Julie Favé retweeted
Do not miss this incredible paper from David Fernandez Antoran's team (with some contribution from my team). The paper introduces epithelioids as a powerful 3D culture system for 8 different human tissues, for longitudinal in vitro studies of human epithelia. Great thread below.
🚨#Preprint alert! @antoranlab in close collaboration with @martincorena lab How can we study human #epithelial tissues for months in the lab, while preserving their native structures and behaviour but without passaging? #human #epithelioids biorxiv.org/content/10.64898…
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Marie-Julie Favé retweeted
Arguably the most boring step in genomics is the first one: normalization. Settled science. Scale + log. Move on. Except that here's been a huge blind spot in the field. And it matters for AIxBio. A 🧵about what I think may be one of the most important papers I've written. 1/
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We also showed how mCAs impact blood transcriptomes, implicating stabilizing selection as a mechanism by which copy number gain mutations are tolerated in healthy blood.
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Collectively, mapping the landscape of autosomal mCAs in populations of diverse ancestry illustrates similarities but also highlights important ancestry, geographic, and sex differences.
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My first time awarding a PhD to a candidate, what a precious honour. Keep up the good work, students!
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Marie-Julie Favé retweeted
Big, beautiful trees!! SMART-PTA for whole-genome+transcriptome on thousand of single cells from the normal human esophagus 🤯 Massively scaling up the power of scWGS to build deep phylogenies and chart somatic evolution from birth throughout life. biorxiv.org/content/10.1101/…
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Marie-Julie Favé retweeted
Friends and colleagues, I’ve written a book on effective functional genomics study design, which will be available on Amazon in a couple of weeks. Sharing the TOC to spark interest. I hope students will find it useful! I’ll share updates soon
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Marie-Julie Favé retweeted
In a new preprint led by @TheNikhilMilind, we explored a fascinating paradox: For many traits the number of duplications or loss-of-function (LoF) mutations is correlated with phenotype. Curiously, for most traits, the AVERAGE direction of LoFs and Dups is the SAME. Why?
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Marie-Julie Favé retweeted
First plenary session talk by Marie-Julie Fave on mosaic chromosomal abnormalities in blood across ancestries #ASHG24
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Improving GWAS performance in underrepresented groups by appropriate modeling of genetics, environment, and sociocultural factors biorxiv.org/cgi/content/shor… #biorxiv_genetic
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You can do it come one come on come on little paper
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Marie-Julie Favé retweeted
Our lab has a #molecular lab assistant position available for the next several months that we are looking to fill asap. Flexible hours, part- or full-time. Come join a great team and work on some super cool #fish #genomics projects! @IKGenFisheries @Concordia
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Scientific journals charging for COLOUR FIGURE FEES. Such an 80s vibe.
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We are hiring a tenure-track professor in plant quantitative genetics at @UMontreal! 🧬🌱 You will be working at @IRBV_Montreal, on the site of the #MontrealBotanicalGarden. You don't want to miss this opportunity. Job offer: rh-carriere-dmz-eng.synchro.… DM me for more information.
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