We back longevity biotech companies developing technologies which can significantly extend healthy human lifespan and are scalable for everyone

Joined April 2024
LongGame Ventures retweeted
Exciting news - Vincere has teamed up with Beiersdorf, the company behind leading skin care brands like NIVEA and Eucerin, to develop mitophagy-enhancing molecules for anti-aging skin care! You can learn more and chat with the team at: linkedin.com/posts/vincere-b…
2
2
164
1/n Fun journey continues: Our new @CellStemCell paper out on how the Inherent & Dormant Plasticity of mouse naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells". cell.com/cell-stem-cell/full…
7
28
2
116
16,059
Replying to @slatestarcodex
@slatestarcodex has written a great article on the burgeoning field of embryo selection, featuring our recently launched company @herasight. Scott has used the technology himself and gives an overview of the field - this is an essential read for anyone curious to learn more.
5
21
5
101
24,216
LongGame Ventures retweeted
How can you use Reinforcement Learning to make better proteins and what does a “Move 37” moment in protein design look like? We’re taking a look at ProtRL: a framework for aligning protein language models to your desired distributions using reinforcement learning. Filippo Stocco from Noelia Ferruz' lab is telling us all about how it works, why reinforcement learning is important for protein engineering, and how these proteins perform when tested in our lab at Adaptyv.
1
15
4
44
8,633
LongGame Ventures retweeted
In the sciences, the authority of thousands of opinions is not worth as much as one tiny spark of reason in an individual man. — Galileo Galilei
34
289
31
1,152
86,404
LongGame Ventures retweeted
UK just might become a leader in longevity — watch this great speech in the House of Lords by @mrevgenylebedev:
Landmark speech in UK’s House of Lords yesterday: “By becoming the first country to treat ageing as a medical condition, we can chart a course for more effective interventions and improved health outcomes.” Transcript below @mrevgenylebedev tinyurl.com/uu26htsv
7
4
1
44
3,422
LongGame Ventures retweeted
Why do people avoid directly expressing the desire: "I don't want to die"? It's not just about disappointment: it will happen anyway, so why upset yourself? It's not just about becoming an outcast: people will think you're strange. The fear of death doesn't raise social status. It's about the need for a complete overhaul of one's worldview. Everything must be reassessed. We all consider people whose actions will lead to our death in the future to be bad. But we also can't call those who do nothing, leading to our death, good either. "I don't want to die" is a breakdown of moral principles, if, of course, this desire is overwhelming. "I don't want to die" is a true new ethic, where everything is subordinated to the struggle for existence. You must behave differently if you seriously don't want to die. Calls for the fight for life cause an unpleasant feeling that comes from any moralizing. All these considerations require energy, which the brain deems unacceptable. All these considerations take time to understand what to do. "I don't want to die" is a confrontational position. It's a demand for everyone to act against death. The struggle for existence is a confrontation with the world. Can we do without a struggle? Yes, it has been done before and turned out poorly.
3
3
28
1,193
This paper will make waves in the aging research community and the results will need to be replicated (I would not fully believe it until I see ITP data) but looks very promising. IL-11 and downstream targets are very promising. Congrats to the team and kudos to Singapore! Source: nature.com/articles/s41586-0…
7
23
4
146
7,848
LongGame Ventures retweeted
>90% of UK deaths are caused by ageing, so where do the parties stand on longevity science? I looked through the #GeneralElection2024 manifestos! @UKLabour: no mention @Conservatives: nothing @reformparty_uk: rien @LibDems: - @TheGreenParty: nope @theSNP: nada @Plaid_Cymru: zero
9
7
3
43
4,520
LongGame Ventures retweeted
I am always shocked at the number of bizarre things people do to "optimize" their health and longevity and yet they don't exercise regularly, sleep 7-9 hours, eat fruits and veggies, build intimate bonds and community, or ever relax. They obsess over the 0.1% but not the 99.9%.
43
85
15
695
106,518
LongGame Ventures retweeted
It is not only about living longer, but also about improving the quality of life. Both will be achieved with new anti-aging therapies.
7
33
984
LongGame Ventures retweeted
🔥🔥🔥my 💯 paper is out, congrats 🎈🎉🍾 @Meyer_DH for this amazing story. Aging clocks tick by the noise: we can build aging clocks 🕰️ on accumulating stochastic variation! @CECAD_ @UniCologne @CGA_age @UKKoeln follow 🧵retweet & read now open access: nature.com/articles/s43587-0…
36
85
16
307
92,790