@Less_Sepulveda

🔬♀️Embryologist and stem cell biologist ☕ Coffee addict 🍺 Beer lover 🏊‍♀️🏋️‍♀️🏃‍♀️ Fitness freak ⚠️ Calcium Oxalate kidney stone maker

 London, England
Joined May 2011
  • Tweets1.4K
  • Following850
  • Followers481
134Media
Remembering our much-loved and missed babies. They will never be forgotten 💜🧡🕯️ #WaveOfLight #BLAW #BabyLossAwarenessWeek #BabyLoss #PregnancyLoss
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New Paper Alert 🥳Our work showing that histone modifications are critical for regulating the specification of epiblast and primitive endoderm lineages in rabbit blastocysts has just been published ! rdcu.be/d52Qv
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Maybe my last post here? ---> Follow the lab on 🦋🦋🦋 ! Happily retweeting new preprint: @Paul_Chammas postdoc paper @MRC_LMS , teasing apart Dux vs MERVL in the 2C-like state. Not all 2C-like cells are created equal....
Paul Chammas@Paul_Chammas26 Nov 2024
Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.1101/… (1/8)
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Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.1101/… (1/8)
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Academic Women Association (AWA) is back, with a Christmas networking event 🎄 When: Thursday 5th December, 3.30 pm Where: Ex Libris, 1st floor Commonwealth building, Hammersmith Campus Book Here: lnkd.in/dctgTt48
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Sending love to all of the babies in Heaven and their families on Earth. Shine on in paradise little angels. @allontheboard #BabyLossAwarenessWeek #BabyLoss #BLAW
Sending love to all of the babies in Heaven and their families on Earth. Shine on in paradise little angels.

ALT Sending love to all of the babies in Heaven and their families on Earth. Shine on in paradise little angels.

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Our work establishing the orphan nuclear receptor NR5A2 as an essential regulator of early mouse development is finally out! We show that NR5A2 is required for the development of a viable morula. doi.org/10.1126/science.adg7…

Nr5a2 is dispensable for zygotic genome activation but essential for morula development

Early embryogenesis is driven by transcription factors (TFs) that first activate the zygotic genome and then specify the lineages constituting the blastocyst. Although the TFs specifying the blasto...

science.org
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In April, Professor Petra Hajkova, deputy director of the @MRC_LMS, was awarded the prestigious Cheryll Tickle Medal. This medal is awarded annually to mid-career, female scientists for outstanding achievements in the field of Developmental Biology. lms.mrc.ac.uk/petra-hajkova-…
MRC Laboratory of Medical Sciences (LMS)@MRC_LMS9 Aug 2024
We’re looking back over the first half of 2024 at the outstanding achievements of our #womeninscience at the @MRC_LMS. We’re proud to see our scientists being recognised for their groundbreaking work. Congratulations to all of you!🎉
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Lessly retweeted
EMBO@EMBO25 Jun 2024
EMBO Gold Medal awarded to Elvan Böke @LabBoke to recognize her pioneering research on physiological mechanisms that enable oocytes to stay healthy over decades of dormancy @CRGenomica embo.org/press-releases/embo…

EMBO Gold Medal awarded to Elvan Böke – Press releases – EMBO

The scientist is recognized for her pioneering research on physiological mechanisms that enable oocytes to stay healthy over decades of dormancy

embo.org
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In the spirit of #MentalHealthAwarenessWeek I am really grateful to my colleagues @ImperialMed @MRC_LMS and in the #devtranscon lab for making this a great place to work - massive thanks to Laurence Game for leading us through our local Nature Reserve @ScrubsAction
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Last chance to register for the Women’s Health in the Workplace event, a safe space to discuss health challenges (physical and mental) faced by women in the academic workplace and the policies around them. imperial.ac.uk/events/174591… @ImperialSandC @ImperialMed @imperialcollege

Women’s Health in the Workplace – an Imperial College event

A joint event by the Women’s Health Network of Excellence, Academic Women Association & Women in Academic Medicine

imperial.ac.uk
Ilaria Belluomo@Ilaria_Bell10 Apr 2024
Our next event "Women’s Health in the Workplace" co-hosted by Women’s Health Network of Excellence, Academic Women Association and Women in Academic Medicine, is approaching! More information and registration below 👇 imperial.ac.uk/events/174591…

Women’s Health in the Workplace – an Imperial College event

A joint event by the Women’s Health Network of Excellence, Academic Women Association & Women in Academic Medicine

imperial.ac.uk
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Congratulations to Petra Hajkova ⁦@MRC_LMS⁩ on a tour de force presentation and the award of the Tickle Medal ⁦@_BSDB_⁩
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Preprint alert! With Irene Amblard @CroBeaver @BorisLenhard @ImperialMed @MRC_LMS we dissect a regulatory circuit that operates during mouse caudal body dev to control Cdx2 Spoiler alert - a single motif switch converts a silencer into an enhancer: biorxiv.org/content/10.1101/…

A dual enhancer-silencer element ensures transient Cdx2 expression during posterior body formation

During development, cells express precise gene expression programmes to assemble the trunk of the body plan. Appropriate control over the duration of the transcription factor Cdx2 is critical to...

biorxiv.org
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What a fantastic inspirational talk we had at our last AWA event by Prof Helena Teede! Thank you everyone for coming, stay tuned for the next AWA event in April. #AWA #AcademicWomenAssociation
Surgery and Cancer@ImperialSandC8 Mar 2024
Replying to @ImperialSandC
A huge thank you to the fantastic speaker @HelenaTeede, and to the organisers @HelenaTeede @NinaModerau @Ilaria_Bell @AWHLproject @MRC_LMS, as well as all those who attended. Find out more about the AWA and how you can join ⬇️ imperial.ac.uk/department-su…
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We are hiring a computational postdoc, with @vaquerizasjm! Interested in TEs and epigenetics? DM or email for more info, apply here or via the QR code 🧬 nature.com/naturecareers/job… Please RT.
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1/n Super excited to see our testis organoids paper published!! ijbs.com/v20p1024.htm A thread: In this paper, Led by Aviya Stopel, Cheli Lev and Stav Dahari we show that we can take neonatal testis, dissociate it to single cells and re-assemble it in 3D using Transwell inserts
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Paper alert from the lab 🙌😀We are so excited by the results, that we had to share it! Lots of beautiful images #embryos #microscopy Generation of systemic rabbit chimeras via Induced Pluripotent Stem Cells Reprogrammed with KLF2, ERAS, and PRMT6 biorxiv.org/content/10.1101/…
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📢We have postdoctoral position to develop new livestock iPSCs/ESC. If you are enthusiastic about animal biotech come and join our team @UoNBiosciences. More details here: jobs.ac.uk/job/DEY595/resear…. #biotechnology #stembryos #reprogramming
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The salary for postdoctoral scientists is £36k. Science is global - if the UK is going to be 'the best country for science in the world', we need to be able to recruit the best scientists. Now, we might not be able to - only British scientists can apply.
BBC News (UK)
@BBCNews4 Dec 2023
Salary threshold for skilled worker visas to rise to £38,700 under government plans to cut legal migration levels Follow live bbc.in/3RamgGW
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🔬 Discover the latest in #StemCellResearch! Join our Dec 7 symposium on Stem Cell-based Modelling of Reproduction and development at MRC Laboratory of Medical Sciences. #MedicalSymposium2023 #MRC-LMS 🧬
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