Neuroscientist studying brain aging and disease leading a lab filled with incredible scientists at the @hscrb department. •Asian food enthusiast.
Cambridge, MA
Joined March 2019
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Hot off the press from our lab! Proud to share with you our latest work by Ximerakis et al. where we look at the effects of heterochronic parabiosis in the aging brain and show changes in the transcriptomic profile of some of your *favorite* cell types. 🧠 doi.org/10.1101/2022.01.27.4…
ALT Dog in the snow with trees behind. Text on poster.
Lee Rubin retweeted
What are the latest strategies to reverse the effects of aging on brain function? What drives tissue regeneration in the skin and eye, and how can we harness it to treat age-related disease? Join #NYSCF2025 to find out! Advance registration closes 3/14: conference.nyscf.org/registr…
Lee Rubin retweeted
Check out recent research from @LeeRubinLab, featured on @NatureComms Editors' Highlights page. nature.com/collections/mjkks…
Lee Rubin retweeted
We are excited to welcome our 2023 NYSCF - Druckenmiller Fellows: @AnuHemalatha (@YaleGenetics), Kentaro Iwasawa (@CincyChildrens), Brian J. Joseph (@Columbia), Kaylee Wells (@Harvard), and Jiajie Xu (@MassGeneralNews)! nyscf.org/programs/extramura…
@alviratyagi , a 2nd year undergrad in our lab, recently attended the Northeast Regional Meeting of the Society for Developmental Biology (NESDB) with Kaylee Wells her postdoc mentor. Alvira presented her work on the potential role of the protein GDF11 on myelination during aging
We are so proud of you @alviratyagi !! Great job on both the poster and talk. #Rubinlab #scientist #harvardcollege #undergrads
Congratulations to one of our most talented and hardworking RAs in the lab. We wish you all the best Sabrina and look forward to your future career in science!! A prestigious award for a truly brilliant student. We are extremely proud of you @sabrina_ghosh 👏🏻#gatesscholar
.@sabrina_ghosh, research asst in the @LeeRubinLab, has received a prestigious Gates Cambridge Scholarship and will be starting her PhD at @Cambridge_Uni this fall. Congratulations Sabrina! bu.edu/articles/2023/young-a…
Congratulations to our undergrad in the lab @riomclellan on her terrific work in the lab and for winning multiple prestigious awards for her thesis! Bravo 👏🏻👏🏻👏🏻 Rio will be graduating this May from Harvard College and will be pursuing graduate school. Congrats Rio!
A HUGE❗️ congrats to @riomclellan on her undergrad thesis being awarded both the John E. Dowling Thesis Prize AND Hoopes Prize for oustanding research!!! (this thesis was as long as my PhD thesis lol).
Work conducted in @LeeRubinLab and @HSCRB!
mcb.harvard.edu/department/n…
Lee Rubin retweeted
New research from @LeeRubinLab in @stemcellreports opens up new avenues for studying inflammatory responses and their regulation in human #astrocytes and serves as a platform to identify therapeutic drugs for #Schizophrenia. cell.com/stem-cell-reports/f…
Congratulations to @methxim and Kristina for all of their hard work in this paper! 👏🏻 And of course to the rest of the lab for their support and time in pushing this paper out. 👏🏻 We now have more insights into the aging brain and hope to bring more to the field (1/2)
Excited to see this in @NatureAging. We profiled mouse brains following parabiosis to identify changes involved in the rejuvenation & aging acceleration driven by blood factors. Congrats to @LeeRubinlab @jzlevin AvivRegev AmyWagers @HSCRB @BroadInstitute | nature.com/articles/s43587-0…
(2/2) With our ongoing studies in the lab looking into the changes we observe in this model. #aging #science #parabiosis
Congratulations to @CescoLime 👏🏻for this publication hot off the press! This differentiation paper shows how to generate lower induced motor neurons (liMoNes/liMNs). Find out more in the paper here: cell.com/cell-reports/pdf/S2… #stemcells #science
New in @CellReports: A new protocol to generate spinal motor neurons from hundreds of #stemcell lines and analyze #gene expression at a single cell level, in a pooled fashion and in parallel. cell.com/cell-reports/fullte…
Congratulations @CescoLime and @MordesLab on this review!
Recently published in @FrontiersIn: Pluripotent #stemcell strategies for rebuilding the human brain @CescoLime @MordesLab frontiersin.org/articles/10.…
Lee Rubin retweeted
Excited to share this manuscript-the first from our bi-coastal collaboration between the Ritz/Khurana/Rubin labs using iPSC-derived dopamine neurons to learn more about the role of pesticides in Parkinson's Disease
biorxiv.org/content/10.1101/…
@beate_ritz @khurana_lab @LeeRubinLab
📢 We have a postdoctoral fellow position available within the skeletal muscle group in our lab at Harvard University. A thorough understanding of satellite cell biology and skeletal muscle regeneration is required. Please send a research statement and CV to [email protected]
(2/2) Experience in mouse and human skeletal muscle cell culture and cell transplant into a variety of mouse models is desirable. #sciencejob #postdocopening #ScienceTwitter
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Excited to be a part of this awesome team!
Here’s some of what I’ve been up to with @LeeRubinLab: Heterochronic #parabiosis reprograms the mouse brain transcriptome by shifting #aging signatures in multiple cell types
What can parabiosis do for you? biorxiv.org/content/10.1101/…
@methxim @rmgiadone Bravo to the team! Not everyone is tagged so please tag any co-authors you might know have a Twitter account. Happy reading to all!
Lee Rubin retweeted
Excited to share our preprint showing that parabiosis regulates aging hallmarks by shifting aging-induced changes of the transcriptome in multiple brain cell types. Great teamwork between @LeeRubinlab @jzlevin AvivRegev AmyWagers | @HSCRB @BroadInstitute | biorxiv.org/content/10.1101/…