Husband, Father, Ophthalmologist, Current Chair of the Prince William County School Board. Youngstown born and raised. Tweets are all my own.
Manassas, VA
Joined August 2016
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.@NIHDirector_Jay highlighting the groundbreaking discovery in MS, ALS, and macular degeneration by @UVA @uvahealthnews research Dr Jay Ambati. New treatments are closer than they ever have been for some of the most difficult medical challenges we face.
🔬Traditional treatments for multiple sclerosis (MS) can help mitigate a patient’s symptoms or keep them from returning.
Now, new NIH-funded research suggests that a modified drug historically used for treating HIV and Hepatitis B could potentially reverse the disease’s effects.
Learn more ➡️ bit.ly/4rwr37x
Babur Lateef, MD retweeted
🔬Traditional treatments for multiple sclerosis (MS) can help mitigate a patient’s symptoms or keep them from returning.
Now, new NIH-funded research suggests that a modified drug historically used for treating HIV and Hepatitis B could potentially reverse the disease’s effects.
Learn more ➡️ bit.ly/4rwr37x
RT @InflammasomeTx: We’re please to see that our K9 discovery in multiple sclerosis has garnered the attention of the HHS and NIH!
This quoted post is unavailable.
Babur Lateef, MD retweeted
Big potential shift in MS research. An experimental drug from Inflammasome Therapeutics (K-9) didn’t just stop further damage in a multiple sclerosis mouse model, it helped animals recover vision and movement they had already lost.
NEWS: Modified HIV drug reverses vision loss and paralysis in multiple sclerosis model.
Read the full story ➡️ bit.ly/4rwr37x
ALT Press release title on a blue background reads: "Modified HIV drug reverses vision loss and paralysis in multiple sclerosis model." NIH logo at the bottom.
Babur Lateef, MD retweeted
We’re excited to showcase a new paper published in Science Translational Medicine on K9 reversing paralysis and vision loss in multiple sclerosis!
Read the full article and news release from the NIH below:
science.org/doi/10.1126/scit…
nih.gov/news-events/news-rel…
Incredible results from @UVA , @uvahealthnews research physician, Dr. Jay Ambati, and his team developing treatments for MS, ALS, macular degeneration, and other neurodegenerative diseases!
Congrats to the team @InflammasomeTx and strong work to revolutionize treatments for MS , ALS, macular degeneration and other neurodegenerative diseases!
Message to Americans living with multiple sclerosis (MS): There is Hope!
Thanks to the groundbreaking research taking place under @POTUS' and @SecKennedy's leadership, a new study by the @NIH has found promising results in reversing pre-existing vision loss and paralysis in MS models.
Learn more 👇
Inflammation Matters⬇️⬇️⬇️
We’re honored to see Inflammasome Therapeutics highlighted by The New York Times Magazine in its exploration of chronic inflammation and the promise of targeting inflammasomes to treat diseases including geographic atrophy and ALS.
The article discusses our programs for geographic atrophy and ALS and quotes our co-founder, Jayakrishna Ambati:
“This is something that could reach patients literally in the next 18 to 24 months.”
We are grateful to see this important area of science and its potential to translate into meaningful therapies for patients receive international attention.
Read the full article:
nytimes.com/interactive/2026…
Remarkable results for K8, a novel therapeutic for Geographical Atrophy, presented this AM at the American Society of Retina Specialists in Montreal. @InflammasomeTx
Inflammasome Therapeutics announces positive Phase 2 data from the 6-month Geographic Atrophy trial of Kamuvudine-8 (K8). The trial showed up to a 54% efficacy in slowing disease progression, 4-letter visual benefit compared to controls, 0 safety signals, and 3-month injection durability
businesswire.com/news/home/2…
Nice piece in @WSJ citing the work done by Dr Ambati and @InflammasomeTx on repurposing drugs. Incredible potential brewing….
Our work on NRTIs and Alzheimer's disease was highlighted today in the Wall Street Journal op-ed "You Can Teach an Old Drug New Tricks," and in the policy report it links to from the University of Chicago & Duke Margolis Institute on pull funding for generic drug repurposing.
wsj.com/opinion/you-can-teac…
Across 270,000+ patients in two major health databases, NRTIs are HIV drugs that also block inflammasomes and cut Alzheimer's risk by 6-13% per year of treatment, potentially preventing ~1 million new cases annually (Alzheimer's & Dementia). The same inflammasome biology drives diabetes too, where NRTIs reduce risk by 33% (Nature Communications).
The next chapter: K8 and K9, our next-gen inflammasome inhibitors (Kamuvudines), are the direct descendants of this work, safer, more potent, and already in clinical trials.
UChicago/Duke Margolis pull funding report:
marketshaping.uchicago.edu/w…
UVA Health on NRTIs & Alzheimer's disease:
uvahealth.com/news/hiv-drugs…
UVA Health on NRTIs & diabetes:
uvahealth.com/news/hiv-drugs…
Incredible work being done @InflammasomeTx on geographic atrophy (macular degeneration) with Dr Ambati! Please check it out!
At Inflammasome Therapeutics, we’re developing new therapies for retinal and neurodegenerative diseases!
In the latest episode of Retina Synthesis, Dr. Jayakrishna Ambati, Founder of Inflammasome Therapeutics, discusses Phase 2 clinical trial results for Kamuvudine-8 (K8), a novel inflammasome inhibitor, in Geographic Atrophy.
youtu.be/TtIWp3qKe00?si=CS6N…
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Babur Lateef, MD retweeted
Well said Secretary Frazier! 💪@AgForestryVA. Gov. Spanberger shouldn’t allow tens of thousands of predatory “skill” slot machines on every Virginia street corner. Make Virginia’s gaming fairer & safer first @GovernorVA @VaAgComm @ltgovhashmi @jonesjay
Babur Lateef, MD retweeted
Alexandria Councilman Canek Aguirre asking state lawmakers to oppose a bill legalizing “skill” slot machines, citing the harmful impacts on local business owners.
Bravo @CanekForCouncil Well done.
Link to story in @AlexandriaNow alxnow.com/2026/02/05/counci…
Babur Lateef, MD retweeted
“Skill” slot machines have operated for years in violation of state law.
Legalizing slot machines in every corner store REWARDS bad actors & sets a terrible precedent for how to do business in Virginia.
…and @GovernorVA said the focus was on affordability & cost of living.
Babur Lateef, MD retweeted
"Have we no sense of decency?"
Virginia does NOT need "iGaming”-casino gambling on cell phones 24/7/365 days a year. Cell phone roulette has terrible outcomes: Addiction among kids & adults skyrocket. Bankruptcies spike.
VOTE NO on HB161-gambling 24/7 at home/work/school.
Babur Lateef, MD retweeted
Inbox: A former Director of National Compliance for skill game developer Pace-O-Matic has pled guilty to money laundering for funneling "hundreds of thousands of dollars in payments from non-compliant distributors and operators" through an LLC instead of reporting the issue.
Let’s Go! @LilyForDelegate
