Lambe Lab at University of Toronto, Optophysiology Neurodetectives
Stanford, Yale, now UTORONTO
Joined June 2019
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CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s disease
rdcu.be/dya6m @Transl_Psych
#rosmap investigation by Jonas Rybnicek aka @Knedlajz2 of @LambeLab with amazing collaborators @neuronJoy and @DanielFelsky (1/5)
This afternoon at @physiologyuoft @uoftmedicine
THIS FRIDAY! Learn from the past with @TerenceKeel, explore the present with @KcD_PhD & @TheRealDrDukes, and help chart a diverse, inclusive future with keynote, @phdgprotein86. We can't wait to introduce our guests to the @uoftmedicine community! RSVP: tinyurl.com/5xk6z7p9
Thank you to our wonderful co-authors, collaborators, and @CIHR_IRSC. We gratefully acknowledge the #rosmap individuals and their families. (5/5)
Exciting to have had the opportunity to investigate key questions about human CHRNA5 #nicotinic receptors, especially in aging and #Alzheimers
@Transl_Psych paper link: rdcu.be/dya6m
🐁Now back to mice to figure out the mechanism! @physiologyuoft @uoftmedicine
Vental hippocampal #CCK interneurons gate contextual reward memory cell.com/iscience/fulltext/S…
@iScience_CP
We braved the hippocampus because of a great collaboration 🙂 Elegant work by Robin Nguyen from @jckimlab and Sanghavy Sivakumaran aka @Luna3150 from @LambeLab
@Luna3150 @physiologyuoft used optophysiology to show that #CCK interneurons inhibit ventral hippocampus neurons tagged with #retrobead labelling from the nucleus accumbens. Great working with @jckimlab again!
ELambe retweeted
Had such a great time working on this with @jblaze8911, from post-talk idea to publication. So happy to see it out in @npp_journal! Congratulations @EricJNestler @AkbarianLab @VannaZachariou
We're so proud of the team effort that went into this one! Check out our recent publication in @npp_journal linking tRNA epitranscriptomics with opioid use @JDCalebBrowne @EricJNestler @AkbarianLab @VannaZachariou
nature.com/articles/s41386-0…
Great study on the lasting impacts of early life stress
biologicalpsychiatryjournal.…
Our paper now out in @BiologicalPsyc1 Early life stress induced disruption in serotonin networks and sex-dependent improvement on anxiety with mOFC serotonin fiber stimulation. Led by @RamkumarRaksha @moriah_edge biologicalpsychiatryjournal.…
ELambe retweeted
Our latest #preprint on touch encoding in rodent mechanoreceptors is out now! 👈
🔗 biorxiv.org/content/10.1101/…
Many thanks to the huge, collaborative effort from the @PrescottLab that spans (most of) my PhD! 🥳(@Chris_Dedek @AHalawa99 @SickKidsNews @bme_uoft) (1/4)
ELambe retweeted
New work from my lab led by Hongli Wang and @heatherkortega. We studied ACh and NE signaling in the mouse medial frontal cortex, while the animal 🐭 plays a competitive game with a computer 🖥️.
biorxiv.org/content/10.1101/…
ELambe retweeted
1/Today is #BellLetsTalk Day! Dr. @rajjitarek Executive Director of TDRA, et al, received a @Bell_LetsTalk/@BrainCanada grant to advance their research on enhancing theta burst stimulation for #depression.
Read parts 2 and 3 for updates on the work!
Thought-provoking afternoon @CureGRIN Roundtable. Patient/family perspective and cool research together!
Great to discuss impact of NMDA receptor loss and rescue: rdcu.be/ds2FP
Work @npp_journal by @sridevi292 @binko_mary @camielnik in @ajr937 & @LambeLab laboratories
#Psychedelics, #serotonin, and beyond:
Neuroscience pioneer and wonderful mentor.
Thanks @NatureNeuro
Miss you, George! rdcu.be/drifk
