Prescott Lab at SickKids and @UofT. Investigating the biophysical basis of #computation & the computational basis of #pain. š§ ā” Tweets by Steve & lab.
Toronto, ON
Joined September 2022
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Our latest work uses @RAMalgoTheRobot to investigate the role of different somatosensory afferents in pain sensitivity š¢
Quantifying the contribution of somatosensory afferent types and changes therein to pain sensitivity using transcutaneous ... biorxiv.org/cgi/content/shorā¦ #biorxiv_neursci
Our latest work led by @laurmedlock on touch encoding in rodents is out now and featured by @SfNtweets!
š Read it here: jneurosci.org/content/44/46/ā¦
Out now in @SfNJournals! š Our latest work on touch and vibration sensing in rodent mechanoreceptors.
A beautiful experimental and modelling collaboration thanks to Dhekra Al-Basha, @Chris_Dedek, @AHalawa99 and the whole @PrescottLab team.
jneurosci.org/content/44/46/ā¦
Interested in Na+ channels and pain?
Come talk to Stephanie at #SfN2024 about our recent work showing that different Nav channel combinations can yield similar excitability in nociceptors!
š” Monday 8-12pm at 165.18
Prescott Lab retweeted
Iām at #SfN2024 presenting my latest work on spinal receptive fields and pain.
We show that spatially and temporally disorganized stimuli preferentially activates inhibition!
Come chat about the implications for therapeutic neuromodulation on Sunday from 1-5pm at 112.01 š¤©
Prescott Lab retweeted
First in-person #RitaAllenFoundation meeting since the pandemic! It was fantastic to learn about so much great science and meet so many generous, open-minded people. And a big shout-out to the #PainScholars ! I encourage everyone to apply and join the foundation!
Prescott Lab retweeted
We thank Dr Steven Prescott @PrescottLab for being with us at IISER Pune and sharing his expertise
Inconvenient but trueā¦ different Nav channel combinations can yield similar excitability in nociceptors ā”ļø
Thanks for sharing @KhannaLabUF!
HOWZAT!!!
"Degeneracy makes it impossible to claim w/o reservation that one NaV subtype is uniquely responsible for pathological pain" š¤Æ
@eLife: Similar excitability through different NaV channels & implications for analgesic efficacy of selective drugs doi.org/10.7554/eLife.90960.ā¦
Prescott Lab retweeted
Iām presenting on spatiotemporal processing and spinal receptive fields tomorrow at #CAN2024 š
Stop by P3-D-439 for a lilā neural coding!
The Prescott Lab is at #CAN2024 in beautiful Vancouver šļø
Stop by @Chris_Dedekās poster today to meet @RAMalgoTheRobot and see our latest work in robotics, machine learning, and pain.
If you are interested in @RAMalgoTheRobot for your lab, please get in contact! š¤
thetransmitter.org/methods/rā¦
This just in: There are better ways to perform nociceptive behaviour tests! Read the latest @_TheTransmitter article highlighting the importance of reducing variability, including our work in the @PrescottLab!
thetransmitter.org/methods/rā¦
Congratulations to the team! Very exciting work.
1. Excited to share our improvement of pain testing in rodents. No more back-breaking inconsistent poking of mouse paws. We present the ARM (Automated Reproducible Mechano-stimulator). 1/7
biorxiv.org/content/10.1101/ā¦
Excited to be part of this incredible work by @SpinalCordMark and @VAbraira, out now in @NeuroCellPress! š
authors.elsevier.com/c/1iiyeā¦
In this work, @laurmedlock uses a network model to show how PV+ inhibitory neurons in the deep dorsal horn gate cutaneous-evoked muscle activity.
Check out this great summary of our latest work in @NeuroCellPress on high-frequency #SpinalCordStimulation. ā”ļø Thanks @MCapogrosso and @scott_lempka!
Together with an Evan Roger and @scott_lempka we published today a preview to the beautiful work from @PrescottLab detailing the effects of High-Frequency spinal cord stimulation on sensory axons! We need more of these works in the field! #neurotech authors.elsevier.com/a/1iZ6Zā¦
Prescott Lab retweeted
Our latest #preprint on touch encoding in rodent mechanoreceptors is out now! š
š biorxiv.org/content/10.1101/ā¦
Many thanks to the huge, collaborative effort from the @PrescottLab that spans (most of) my PhD! š„³(@Chris_Dedek @AHalawa99 @SickKidsNews @bme_uoft) (1/4)
Prescott Lab retweeted
Check it out!!! @RAMalgoTheRobot is going to change the game for measuring #pain in rodent models!
Huge congratulations to @Chris_Dedek and @PrescottLab! šš¤©
Want to learn more about me? š¤ My instructions and impressive capabilities are now published in @CellRepMethods.
Proudly created by @Chris_Dedek and the @PrescottLab
#PainResearchForum #Pain #RodentBehavior
cell.com/cell-reports-methodā¦
Prescott Lab retweeted
Want to learn more about me? š¤ My instructions and impressive capabilities are now published in @CellRepMethods.
Proudly created by @Chris_Dedek and the @PrescottLab
#PainResearchForum #Pain #RodentBehavior
cell.com/cell-reports-methodā¦
20 years ago, Chesler et al. showed that the greatest source of variability in evoked pain responses was the experimenter. This is at the core of poor reproducibility.Ā @chris_dedek built @RAMalgoTheRobot to fix that. š¤
Out now in @CellReportsMethods!
cell.com/cell-reports-methodā¦
Plus, follow @RAMalgoTheRobot for all the latest updates!
xitter.cf/RAMalgoTheRobot/statusā¦
#ReproducibilityInScience #MouseBehavior #Painresearch
Want to learn more about me? š¤ My instructions and impressive capabilities are now published in @CellRepMethods.
Proudly created by @Chris_Dedek and the @PrescottLab
#PainResearchForum #Pain #RodentBehavior
cell.com/cell-reports-methodā¦