@LLGoede

Research fellow @netstim_org lab | @BWHNeurology @Brain_Circuits // account will be inactive soon // Please follow at https://xitter.cf/t.co/3rlWBMi8io

 Berlin, Deutschland
Joined August 2020
  • Tweets133
  • Following275
  • Followers371
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Can we stimulate brain networks identified using deep brain stimulation from the outside, in a non-invasive fashion? At @Brain_Circuits, we believe, we can! Our first randomized clinical trial demonstrating this concept is just out in @MDJ_Journal: doi.org/10.1002/mds.29940 A🧵
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You can now find me at Bluesky: lukasgoede.bsky.social – come follow along as I transition over!
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I had a wonderful conversation with @shansiddiqi today about bringing human brain connectomics to clinical practice in psychiatry. Tune in for the latest & greatest updates on TMS, depression, PTSD, causality and more! 👇👇 stimulatingbrains.org/61-sha…
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Lukas Goede retweeted
Michael Fox@foxmdphd21 Oct 2024
How close are we to at home brain stimulation? Important positive trial of home tDCS for depression just out in @NatureMedicine.
nature
@Nature21 Oct 2024
A device that delivers a small electrical current to the brain has beneficial effects in cases of depression that doesn't respond to drugs or therapy go.nature.com/3BTMQ3e

Brain stimulation at home helps to treat depression

Nature - A device that delivers a small electrical current to the brain has beneficial effects in cases of depression that doesn't respond to drugs or therapy.

nature.com
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Very well deserved! Huge congrats! Very happy to be part of the @netstim_org team under your fantastic guidance, @andreashorn_!
Andreas Horn@andreashorn_20 Oct 2024
Excited to be recognized with the @brainstimj @ElsevierConnect Early Career Award 2025! Big thanks go out to the fantastic individuals in my lab without whom none would be possible! See you in Kobe – who else is coming? @Brain_Circuits @netstim_org elsevier.com/events/conferen…
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Excited to be recognized with the @brainstimj @ElsevierConnect Early Career Award 2025! Big thanks go out to the fantastic individuals in my lab without whom none would be possible! See you in Kobe – who else is coming? @Brain_Circuits @netstim_org elsevier.com/events/conferen…
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Can we use a convenient dry-EEG setup to program DBS electrodes? @bahnebahners & @LLGoede say yes – tweetorial below 👇👇
Bahne Bahners@bahnebahners7 Oct 2024
🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – each time asking the patient to perform motor tasks to see how things improve. Could we use DBS-#evokedpotentials to guide programming?doi.org/10.1101/2024.10.04.2…
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Once defined, we can now use this #pattern to estimate #DBSoutcomes in #unseen patients. Would the model be able to identify the optimal DBS contacts?🥁🥁🥁 Indeed: in all of the five cases tested, the model selected the optimal DBS contact correctly!🥳
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Using this #dryEEG setup, we recorded DBS-#evokedpotentials in 58 hemispheres in people with #Parkinson’s disease and computed a model which represents the optimal DBS-evoked #responsepattern associated with maximal DBS improvements
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Excited to share our preprint on a new approach using DBS-evoked potentials to streamline DBS programming! Big thanks to @bahnebahners, @andreashorn_, and all the coauthors! Follow this thread to learn more! 👇 @netstim_org @Brain_Circuits @ChariteBerlin
Bahne Bahners@bahnebahners7 Oct 2024
🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – each time asking the patient to perform motor tasks to see how things improve. Could we use DBS-#evokedpotentials to guide programming?doi.org/10.1101/2024.10.04.2…
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🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – each time asking the patient to perform motor tasks to see how things improve. Could we use DBS-#evokedpotentials to guide programming?doi.org/10.1101/2024.10.04.2…
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Mass General and @harvardmed Investigator Gary Ruvkun, PhD, has won the 2024 @NobelPrize in Physiology or Medicine. He is honored for his discovery of small regulatory RNAs. Congratulations! Learn more: spklr.io/6019vzIW
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Super proud of @bahnebahners for representing the lab & @Brain_Circuits at @movedisorder and for this fantastic award that led to a talk in front of 4000 dear colleagues & to being featured in the MDS podcast recently! Very well done Bahne and very well deserved!! 👏👏🎉🎉🥳🎊
MDS@movedisorder28 Sep 2024
Congratulations to Junior Awardees Edwin Jabbari and Bahne Bahners for their contributions to clinical/basic science research in the field of Movement Disorders. #MDSCongress
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Merging connectomics, network models and physiology? Yes please! Bahne Bahners drops the ‘mic’ in his junior award winning talk #mdscongress on how DBS works; how we can use this information to optimize DBS programming. ⁦@leaddbs⁩ ⁦@andreashorn_⁩ ⁦⁦@foxmdphd⁩
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Congratulations for graduating your PhD with summa cum laude, Dr. @Bassam_Al_Fatly – very well deserved and it has been a real honor and pleasure to co-mentor you! Bassam’s works including three first-authorships in @Brain1878 and many new innovations: scholar.google.com/citations…
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(1/12) Our brain network study of religious fundamentalism is out in PNAS. We identified brain networks associated with religious fundamentalism and found shared neuroanatomy with lesions linked to confabulation and criminal behavior: pnas.org/doi/10.1073/pnas.23…
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Lukas Goede retweeted
Michael Fox@foxmdphd22 Aug 2024
Can we use DBS evoked potentials to guide programming? @bahnebahners presenting @DBSThinkTank suggests we’re getting close! @netstim_org @Brain_Circuits
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DBS Think Tank XII starts tomorrow in Gainesville, FL! Tune in at 12:50pm EST for a welcome and opening remarks from @MichaelOkun and @KDFooteMD The first session moderated by @littleneuro starts at 1pm EST If you have not registered virtually, go ⬇️ ufl.zoom.us/webinar/register…
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One of our participants kindly shared their firsthand perspective of working with us on developing real-world adaptive deep brain stimulation for Parkinson’s Disease in this insightful article @nytimes. nytimes.com/2024/08/19/healt…

A Personalized Brain Pacemaker for Parkinson’s (Published 2024)

In a new frontier for deep brain stimulation, researchers used A.I. to develop individualized algorithms, which helped a skateboarder and other patients with Parkinson’s disease.

nytimes.com
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In a short randomized trial, tDCS targeting a DBS-implicated network improved PD motor features compared to sham stimulation. 11 participants underwent DBS for clinical purposes & improvements with tDCS in the trial correlated w/ motor improvement with DBS loom.ly/Fu7Dya4

Linking Invasive and Noninvasive Brain Stimulation in Parkinson's Disease: A Randomized Trial

Background Recent imaging studies identified a brain network associated with clinical improvement following deep brain stimulation (DBS) in Parkinson's disease (PD), the PD response network. Object...

movementdisorders.onlinelibrary.wiley.com
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Can we non-invasively target a network identified by DBS to be potentially effective for Parkinson's? You bet we can and Goede, Horn and colleagues show us the path @MDJ_Journal in a new prospective, randomized, double-blinded, crossover trial in 21 folks. movementdisorders.onlinelibr…
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