@JosiePyrah

Researcher & #preLighter, host-pathogen interactions and imaging, fungal and bacterial pathogens, into books, running and baking

 Sheffield, England
Joined March 2018
  • Tweets123
  • Following426
  • Followers236
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Very happy to see our new paper out in @PLOSPathogens! Interested in fungal infection dynamics? Have a read about cryptococcal dissemination from blood vessels in the zebrafish infection model #infection #zebrafish #microscopy @JohnstonLabs @phil1pingham
PLOS Pathogens@PLOSPathogens26 Apr 2022
During infective meningitis, Gibson et al. show that Cryptococcus can block small blood vessels, proliferate & cause vasodilation. Blockages can result in microbes being transported into tissues & infection being spread by vessels bursting. @josiepyrah plos.io/3MvCbfb

Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of...

Author summary Meningitis is a life threatening form of infection in the brain that is difficult to treat. How infection spreads from the blood to cause meningitis is not well understood. Here we...

journals.plos.org
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Josie Pyrah retweeted
preLights@preLights12 Apr 2022
Enlightening anti-inflammatory signalling in immune responses Josie highlights work by @elkslab_sheff and colleagues prelights.biologists.com/hig…
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Sheffield half done! Awesome support for the whole route!
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The Steel City sparkling in the sunshine on #SheffieldHalfMarathon day. What incredible support!!! 🏃‍♀️🏃‍♂️✨
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We got away with it! Dry but cold conditions. We enjoyed return of “The Puddle”. The first we’ve seen of it since our return. A big thanks, as always, to everyone who makes our event what it is. Here’s the link to today’s run report parkrun.org.uk/hillsborough/…
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Josie Pyrah retweeted
Foster Lab@foster_lab3 Nov 2021
Our latest paper about the mechanism of antibiotic killing is now out! Another great piece of collaborative research @Laia_Pasquina @LafageLucia @JosiePyrah @AKTooke @ivvpanchal
Molecular Microbiology Sheffield@MM_Sheffield30 Oct 2021
Another beautiful paper from @foster_lab, @Sheffield_AFM, @PerBullough & @steverenshaw in @sheffielduni. Unraveling the mechanisms of antibiotic killing of bacteria using a combination of molecular microbiology and incredible imaging using AFM and EM pnas.org/content/118/44/e210…

Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action...

Bacterial cell wall peptidoglycan is essential, maintaining both cellular integrity and morphology, in the face of internal turgor pressure. Peptid...

pnas.org
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Really excited to see our recent study in @PLOSPathogens!🎊We examined the mechanism of augmentation in S. aureus infection and found commensal bacteria protect S. aureus from ROS within macrophages, follow the link to read more! @GracePidwill @foster_lab journals.plos.org/plospathog…
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Remember when Alexander Fleming discovered penicillin in 1928? Now, almost 100 years later, we know how it actually works! A team of researchers with @bmssheffield have discovered how these types of antibiotics work to kill the superbug MRSA. Read more👇 sheffield.ac.uk/news/scienti…
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Scientists in South Yorkshire have uncovered the precise way a type of antibiotic works to attack bugs, potentially paving the way for new treatments: bbc.in/3GoUP6g
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Commensal bacteria augment #Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species Read the full paper from Josie Gibson, @GracePidwill, @steverenshaw, Simon Foster and colleagues @sheffielduni buff.ly/2Z0eDLP
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Awesome paper congrats!
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Our virtual symposia are fast approaching, only 1 week left to register for #StaphGBI2021 and #Florey2021 More information on talks and keynotes: floreyinstitute.com/2021---f… Link to registration only: forms.gle/S8RSNAF8WJ91akX66
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Josie Pyrah retweeted
preLights@preLights20 May 2021
Don't miss out! Our call is open until tomorrow 🧑‍🔬👩‍🔬
The Company of Biologists@Co_Biologists20 May 2021
Two days left to apply to join the @preLights team - deadline Friday 21 May (ow.ly/A5gQ30rIiRL). Curious to know more? Hear from the preLighters: youtu.be/jOEbKHbjFaI #preprints
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Josie Pyrah retweeted
preLights@preLights13 Apr 2021
A Dram(1)-atic response to Salmonella infection preLight by @JosieFGibson on work by @SamrahMasud, @MeijerAnnemarie and colleagues prelights.biologists.com/hig…
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A Dram(1)-atic response to Salmonella infection. A new highlight about an interesting study examining the role of autophagy modulator Dram1 in Salmonella infection, with thoughtful comments from the authors @MeijerLab @preLights prelights.biologists.com/hig…

Dram1 confers resistance to Salmonella infection - preLights

A Dram(1)-atic response to Salmonella infection

prelights.biologists.com
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Josie Pyrah retweeted
Josh Sutton@MrJafs1 Apr 2021
So excited to be able to share my first first-author paper in PLOS Pathogens! This the product of my PhD and I'm so happy for it to be out in the world. Thanks to the @foster_lab and all our collaborators! And thank you @DiMeN_DTP for funding my PhD and making this possible! 🥳
PLOS Pathogens@PLOSPathogens1 Apr 2021
.@MrJafs, @foster_lab and colleagues @SheffieldMBB @UniofNewcastle demonstrate the importance of appropriate #cellwall structure and dynamics during #Staphylococcus aureus pathogenesis, providing new insight to the mechanisms of disease. buff.ly/3dtdqQK
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Exciting paper on S. aureus cell wall during infection! Congrats @MrJafs!!
PLOS Pathogens@PLOSPathogens1 Apr 2021
.@MrJafs, @foster_lab and colleagues @SheffieldMBB @UniofNewcastle demonstrate the importance of appropriate #cellwall structure and dynamics during #Staphylococcus aureus pathogenesis, providing new insight to the mechanisms of disease. buff.ly/3dtdqQK
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