@GracePidwill

University of Sheffield postdoc studying S. aureus host-pathogen interactions.

 Bristol, England
Joined May 2011
  • Tweets19
  • Following123
  • Followers39
Grace Pidwill retweeted
Foster Lab@foster_lab24 Nov 2022
Another new paper from our lab utilising novel probes to reveal more about S. aureus cell wall peptidoglycan dynamics during growth and division pubs.acs.org/doi/10.1021/acs…

Coupling Novel Probes with Molecular Localization Microscopy Reveals Cell Wall Homeostatic Mechan...

Abstract. Bacterial cell wall peptidoglycan is essential for viability, and its synthesis is targeted by antibiotics, including penicillin. To determine ho

pubs.acs.org
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Grace Pidwill retweeted
Foster Lab@foster_lab13 Nov 2022
Our latest paper about the essential function that DivIC plays in S. aureus PG synthesis is out now. Congrats to @MarianaTrejo01 and everyone involved!
Staph papers@Staph_papers12 Nov 2022
The Staphylococcus aureus cell division protein, DivIC, interacts with the cell wall and controls its biosynthesis ift.tt/9TKgx1D

The Staphylococcus aureus cell division protein, DivIC, interacts with the cell wall and controls...

Bacterial cell division is a complex, dynamic process that requires multiple protein components to orchestrate its progression. Many division proteins are highly conserved across bacterial species...

pubmed.ncbi.nlm.nih.gov
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Grace Pidwill retweeted
Angela Nobbs@superstreps14 Oct 2022
Don't miss out! Fully-funded PhD opportunity @BristolUni to explore new strategies to combat neonatal GBS disease. Project details here: uob-fhs.phdprojects.uk/124 Apply here: bit.ly/3S1N0b6
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Grace Pidwill retweeted
Foster Lab@foster_lab15 Jun 2022
Our latest paper on the multiple roles of PBP1 in Staphylococcus aureus cell division is out now! pubmed.ncbi.nlm.nih.gov/3570…

Penicillin-Binding Protein 1 (PBP1) of Staphylococcus aureus Has Multiple Essential Functions in...

Bacterial cell division is a complex process requiring the coordination of multiple components to allow the appropriate spatial and temporal control of septum formation and cell scission. Peptidogl...

pubmed.ncbi.nlm.nih.gov
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Grace Pidwill retweeted
Josie Pyrah@JosiePyrah28 Apr 2022
Very happy to see our new paper out in @PLOSPathogens! Interested in fungal infection dynamics? Have a read about cryptococcal dissemination from blood vessels in the zebrafish infection model #infection #zebrafish #microscopy @JohnstonLabs @phil1pingham
PLOS Pathogens@PLOSPathogens26 Apr 2022
During infective meningitis, Gibson et al. show that Cryptococcus can block small blood vessels, proliferate & cause vasodilation. Blockages can result in microbes being transported into tissues & infection being spread by vessels bursting. @josiepyrah plos.io/3MvCbfb

Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of...

Author summary Meningitis is a life threatening form of infection in the brain that is difficult to treat. How infection spreads from the blood to cause meningitis is not well understood. Here we...

journals.plos.org
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Grace Pidwill retweeted
Nihal Bandara@HMHNBandara7 Apr 2022
Would all interactions between Streptococci and Candida be synergistic or antagonistic? Dr Angela Nobbs from @BristolUni explains now at #microbio22. @MicrobioSoc @superstreps #candida #streptococcus
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Grace Pidwill retweeted
Foster Lab@foster_lab3 Nov 2021
Our latest paper about the mechanism of antibiotic killing is now out! Another great piece of collaborative research @Laia_Pasquina @LafageLucia @JosiePyrah @AKTooke @ivvpanchal
Molecular Microbiology Sheffield@MM_Sheffield30 Oct 2021
Another beautiful paper from @foster_lab, @Sheffield_AFM, @PerBullough & @steverenshaw in @sheffielduni. Unraveling the mechanisms of antibiotic killing of bacteria using a combination of molecular microbiology and incredible imaging using AFM and EM pnas.org/content/118/44/e210…

Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action...

Bacterial cell wall peptidoglycan is essential, maintaining both cellular integrity and morphology, in the face of internal turgor pressure. Peptid...

pnas.org
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Grace Pidwill retweeted
Josie Pyrah@JosiePyrah31 Oct 2021
Really excited to see our recent study in @PLOSPathogens!🎊We examined the mechanism of augmentation in S. aureus infection and found commensal bacteria protect S. aureus from ROS within macrophages, follow the link to read more! @GracePidwill @foster_lab journals.plos.org/plospathog…
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Remember when Alexander Fleming discovered penicillin in 1928? Now, almost 100 years later, we know how it actually works! A team of researchers with @bmssheffield have discovered how these types of antibiotics work to kill the superbug MRSA. Read more👇 sheffield.ac.uk/news/scienti…
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Grace Pidwill retweeted
Angela Nobbs@superstreps14 Oct 2021
Come and join us @BristolUni for an exciting @GW4BioMedDTP PhD deciphering how Streptococcus bacteria cause fatal heart disease! See tinyurl.com/7bpktsrk and tinyurl.com/bhdm8n46 for details. Spread the word!!
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Grace Pidwill retweeted
Foster Lab@foster_lab20 Sep 2021
Our latest paper is out in @PLOSPathogens! Congratulations @JosieFGibson and @GracePidwill on your excellent work determining the molecular basis for the augmentation phenomenon in S. aureus! journals.plos.org/plospathog…

Commensal bacteria augment Staphylococcus aureus infection by inactivation of phagocyte-derived...

Author summary S. aureus is a commensal inhabitant of the human skin and nares. However, it can cause serious diseases if it is able to breach our protective barriers such as the skin, often via...

journals.plos.org
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Commensal bacteria augment #Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species Read the full paper from Josie Gibson, @GracePidwill, @steverenshaw, Simon Foster and colleagues @sheffielduni buff.ly/2Z0eDLP
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It’s finally out! After many years of work, you can now find out more about the impact of the K-Pg mass extinction on snakes in our new paper in @NatureComms nature.com/articles/s41467-0… (1/3)

Evolution and dispersal of snakes across the Cretaceous-Paleogene mass extinction

Nature Communications - Snakes are one of the most successful groups of living vertebrates, but the timing of their diversification is unclear. Combining molecular clocks, fossils, and...

nature.com
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Grace Pidwill retweeted
Foster Lab@foster_lab9 Jul 2021
Massive congratulations to Mariana Tinajero Trejo for coming second in the 15 minute talk category at #StaphGBI2021 #Florey2021 the whole lab is so proud! 🥳
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Grace Pidwill retweeted
Josh Sutton@MrJafs1 Apr 2021
So excited to be able to share my first first-author paper in PLOS Pathogens! This the product of my PhD and I'm so happy for it to be out in the world. Thanks to the @foster_lab and all our collaborators! And thank you @DiMeN_DTP for funding my PhD and making this possible! 🥳
PLOS Pathogens@PLOSPathogens1 Apr 2021
.@MrJafs, @foster_lab and colleagues @SheffieldMBB @UniofNewcastle demonstrate the importance of appropriate #cellwall structure and dynamics during #Staphylococcus aureus pathogenesis, providing new insight to the mechanisms of disease. buff.ly/3dtdqQK
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Grace Pidwill retweeted
Josie Pyrah@JosiePyrah19 Jan 2021
Interested in macrophage-S. aureus interactions and how they shape infection outcome? Our review examines macrophage bacterial killing, and how S. aureus can evade macrophages to cause infection. @GracePidwill @Dr_Joby_Cole @steverenshaw @foster_lab frontiersin.org/articles/10.…
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Our review into macrophage interactions with S.aureus is published today! @JosieFGibson @foster_lab @steverenshaw frontiersin.org/articles/10.…
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Grace Pidwill retweeted
Foster Lab@foster_lab24 Jul 2020
Our latest paper is out in @PLOSPathogens all about how MRSA strains evolve to have high level resistance to β-lactam antibiotics! @SheffieldMBB @FloreyInstitute journals.plos.org/plospathog…

Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA...

Author summary Methicillin resistant Staphylococcus aureus (MRSA) places a great burden on human healthcare systems. Resistance is mediated by the acquisition of a non-native penicillin-binding...

journals.plos.org
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Grace Pidwill retweeted
Foster Lab@foster_lab1 Jun 2020
Come along and listen to Simon talk about all the exciting work happening in the Foster lab
Keenan Lacey@Keenan__Lacey1 Jun 2020
Next up in the Virtual S. aureus Seminar Series is @foster_lab from @SheffieldMBB. Tune in this Thursday, June 4th at 3pm EST. If you haven't done so already, click the link to join the mailing list: bit.ly/34kxCiZ
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