Hello! My name is Jake Files and I’m applying to internal medicine with an interest in combined research residency programs and infectious diseases! My scientific interests include all host-pathogen interactions and specifically viral immunology. #Match2024 #Medtwitter

Thanks goes to @UABMSTP for allowing us to attend and @A_P_S_A for putting on such a great conference! As always, I appreciate @NerdmannID and @OASkye for the support and the exciting science that I was able to present!

Finished Step 2 and my MS3 clinical year this past week and was able to celebrate by attending @JointMeeting! Was able to attend some amazing talks, network with program directors, and even try some deep-dish pizza!

Additionally, while NAE-specific CD4+ T-cell responses correlated with HIV-specific antibodies (IgG Env Ab) in one efficacy trial, this was not found to be the case with CD4 + T-cell responses to AE. 4/5

By using samples from previous HIV vaccine trials, our study shows that certain vaccine epitopes with evidence of immune escape (termed adapted epitopes or AE), elicit weaker CD4+ T-cell responses when compared to non-adapted epitopes (NAE). 3/5

...and a sunset on a lake! Why choose the lakes or the mountains when you can choose both! Gotta love North Carolina. 3/4

Over these last two weeks, I was able to take some time off! Managed to catch a sunrise in the smokies... 2/4

PHD: Pretty Happy to be Done! 2 weeks ago, I successfully defended my PhD dissertation. While it feels great to be done, I am also sad to be leaving. I have greatly enjoyed my time in the lab with @goepfert_paul and many others. 1/4

Still feels surreal to be saying this, but my public defense date is one week from today! 🎉 If anybody would like the zoom link, just DM me.

I was able to listen to incredible speakers, network with other researchers, and meet young trainees like myself. As always, thanks to my mentor @goepfert_paul for this opportunity, and to the UAB Max Cooper Immunology Travel Award! Also managed to grab some incredible pics! 2/2

I was able to present my recent research on CD4+ T cell responses at the Next Generation HIV Vaccines and Therapeutics Keystone Symposia in Banff Canada! #KSHIVVAX22 1/2