Official student-run #ScienceTwitter of the Jackrel Lab at WashU/STL. Studying the biochemistry of protein misfolding, chaperones, & disaggregases
St. Louis, MO
Joined July 2018
- Tweets94
- Following140
- Followers307
- Likes108
Jackrel Lab Members retweeted
Grateful for a 5-yr R01 award from the National Institute on Aging for developing vaccines against neurodegenerative diseases. Thanks to collaborations with @JackrelLab and support from @WashUBME @WashUengineers
Jackrel Lab Members retweeted
Interesting: New paper from @JackrelLab & colleagues reports PDZ serine protease HTRA1 disaggregates #Parkinsons-associated α-synuclein amyloid fibrils & converts them into non-toxic/seeding incompetent species; Future = small molecule HTRA1 modulators
nature.com/articles/s41467-0…
Jackrel Lab Members retweeted
Biofilms are a major public health threat, and biofilm disruption is a key goal. In this new #mBio study, @JackrelLab demonstrates that potentiated Hsp104 variants counter the toxicity and aggregation of PSMα peptides. journals.asm.org/doi/10.1128…
ALT PSMα peptides form foci and vesicle-like structures in yeast.
Jackrel Lab Members retweeted
Feeling excited to join as a Postdoctoral Research Scholar in @JackrelLab in Department of Chemistry, WashU, co jointly with @JaiRudra4 at @WashUBME. Thanks to @SaraogiIshu for all the guidance and support in my Ph. D. at @chm_iiserb @iiserbhopal
Jackrel Lab Members retweeted
Assistant Professor of Chemistry Meredith Jackrel has been awarded an NIH grant to study proteins related to ALS. Congrats to the entire @JackrelLab
artsci.wustl.edu/ampersand/j…
Jackrel Lab Members retweeted
My lab is looking for a technician or a lab manager with experience in synthetic chemistry, molecular biology, or immunology rudralab.wustl.edu/ Please contact me if interested.
Jackrel Lab Members retweeted
Our preprint on the amyloidogenic propensity of cross-beta rich peptide nanofibers in yeast and mammalian cell systems is here. We also report the first DNA vaccine based on amyloid-inspired immune adjuvants. Thanks to @JackrelLab for collaboration biorxiv.org/content/10.1101/…
Jackrel Lab Members retweeted
Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines, interesting study from @JackrelLab: biorxiv.org/content/10.1101/…
Jackrel Lab Members retweeted
Excited that this work from my time with @JackrelLab and @JaiRudra4 is out on BioRxiv! biorxiv.org/content/10.1101/…
Jackrel Lab Members retweeted
The chemistry of quilting: “PhDs are a lot of work, and I wanted something to remember it,” says @MacySprunger, a graduate student in @JackrelLab. “Quilts are a great little way to do that for me."
@WUSTLArtSci @WUSTL @cenmag
cen.acs.org/education/scienc…
ALT Science stitches: Macy Sprunger designed and made this quilt representing her PhD work. (Credit: Macy Sprunger)
Jackrel Lab Members retweeted
#EditorsChoice
Welcome to read "Prion-Like Proteins in Phase Separation and Their Link to Disease" by Macy L. Sprunger and Meredith E. Jackrel.
The article 👉mdpi.com/2218-273X/11/7/1014
The list 👉mdpi.com/journal/biomolecule…
Jackrel Lab Members retweeted
My protocol on performing FRAP on condensates in living yeast cells is out now! Take a look and have a happy Friday! star-protocols.cell.com/prot…
Jackrel Lab Members retweeted
I designed and sewed a quilt that represents my PhD research in @JackrelLab and then I took a picture of it by my bench. Here’s to the sixth and final year 👩🏼🔬🪡🧵
Jackrel Lab Members retweeted
The final version of my MATR3 paper with @JackrelLab is now available on @iScience_CP! Here is a thread 🧵 on our main findings: (1/7)
Jackrel Lab Members retweeted
#GetToKnow the #WashUNeuroCommunity: Meredith Jackrel, PhD (twitterless), PI of @JackrelLab @WashUChem asks how protein misfolding occurs, how it can lead to disease such as Alzheimer’s, Parkinson’s, Huntington’s and ALS, and how protein-remodeling factors can reverse misfolding.
Jackrel Lab Members retweeted
Grad student Jeremy Ryan won a biomedical research fellowship from the @NIH for his project “Engineering and Evolving Substrate-Specific Hsp104 Variants.” Congratulations, Jeremy! @JackrelLab @WUSTLArtSci chemistry.wustl.edu/news/rya…
ALT Jeremy Ryan
Jackrel Lab Members retweeted
Postdoctoral position in protein misfolding disorders with @JackrelLab
Washington University in St. Louis, MO, USA
jobrxiv.org/job/washington-u…
#ScienceJobs
Jackrel Lab Members retweeted
Chemistry graduate student Macy Sprunger won a three-year fellowship from the National Institutes of Health. Congratulations, @MacySprunger! @JackrelLab chemistry.wustl.edu/news/spr…
Jackrel Lab Members retweeted
Check it out: @WUSTLdbbs's own Dr. Meredith Jackrel is featured in a Q&A about her lab's work in developing more effective vaccines for elderly patients. #DBBSProud
Read more here: ow.ly/KqzX50Dm6H7
Jackrel Lab Members retweeted
.@JackrelLab's expertise in protein misfolding and neurodegenerative diseases makes them uniquely qualified to work on developing new, amyloid-inspired vaccine technologies aimed at elderly populations. chemistry.wustl.edu/news/jac…
ALT Graduate students Jeremy Ryan and Macy Sprunger working in Meredith Jackrel's lab in Fall 2019. Photo: Sean Garcia