Psychopharmacology PhD student at @bertogliolab :)
Florianópolis
Joined December 2012
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Check out our new paper! Thanks @bertogliolab and @FarmacoUFSC 🐭💚
📢New lab paper! Ayahuasca (#DMT, #psychedelics) facilitates fear memory extinction in male and female rats via infralimbic cortex & serotonin 1A and 2A receptors. Kudos to @Isabeus_, and thanks @BrJPharmacol, for the support!
bpspubs.onlinelibrary.wiley.…
Isabel Werle retweeted
🆕Excited to share our latest review on psychedelics and fear extinction @Isabeus_ @FarmacoUFSC @fapesc @UFSC journals.sagepub.com/doi/10.…
Isabel Werle retweeted
@PsyPost We greatly appreciate the dissemination of our most recent work on ayahuasca (DMT) as a fear extinction facilitator @Isabeus_ @FarmacoUFSC
psypost.org/scientists-ident…
Isabel Werle retweeted
Como a ayahuasca ajuda a extinguir memórias aversivas? Neste infográfico resumimos os resultados de nosso artigo científico mais recente. Abaixo, o link temporário para acesso gratuito ao PDF desse trabalho. @Isabeus_ @FarmacoUFSC @UFSC #psychedelics
authors.elsevier.com/a/1mHwf…
So glad to see this work published! Thanks to all the collaborators, especially Prof. Leandro. Check the full text here: sciencedirect.com/science/ar…
🆕Lab study shows that ayahuasca enhances fear extinction, including under stress-induced deficits, and reduces fear generalization; cortical BDNF-TrkB signaling contributes to these effects @Isabeus_ @fmrpusp @FarmacoUFSC @UFSC @ecnptweets #psychedelics
sciencedirect.com/science/ar…
ALT Proposed mechanisms of N,N-dimethyltryptamine (DMT), the primary psychoactive compound in ayahuasca, in the rat infralimbic cortex on fear extinction and generalized fear in rats
Thankful to @IBROorg and @SBNeC for this grant! Excited to attend the SBNeC Conference and connect with the neuroscience community!
Isabel Werle from our lab has been awarded the IBRO travel grant to attend the Brazilian Society for Neuroscience and Behavior (@SBNeC) Congress, which will be held from September 8–12 in Águas de Lindóia, SP. Congratulations on your achievement, @Isabeus_! @FarmacoUFSC
Isabel Werle retweeted
Excited to contribute to this piece on CBD effects on anxiety and fear memory, together with @MarinaPort68942, @Isabeus_, @LucianeAlfaia, @mest_prof_fmc, @FarmacoUFSC, and Fernanda Guterres
revistafitos.far.fiocruz.br/…
Isabel Werle retweeted
📢Paper alert! Check out our perspective on #psychedelics and sports, exploring potential benefits, risks, and open questions. @scnpjournal, @MarinaPort68942, @Isabeus_
doi.org/10.1017/neu.2025.13
Isabel Werle retweeted
Check out our new paper in which we review what is currently known on how psychedelics acutely and post-acutely modulate fear conditioning, extinction learning, episodic memory, and semantic memory and how such effects may speak to treatment of PTSD.
link.springer.com/article/10…
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Isabel Werle retweeted
🌟Review Alert! Excited to share our latest article, where we explore the effects of serotonergic #psychedelics and related substances (e.g., MDMA) on extinguishing and reconsolidating aversive memories, expressing fear/anxiety, and locomotion in rodents.
authors.elsevier.com/a/1jq5G…
Isabel Werle retweeted
Congratulations to @Isabeus_ and Aymee for winning the Poster Presentation Awards at the @SBFTEnet Congress! @FarmacoUFSC and Bertoglio lab are proud of your outstanding contributions to research on fear extinction and psychedelics!
Isabel Werle retweeted
#CBD Thrilled to see our book chapter on cannabidiol's effects on fear processing & PTSD published online! Thanks @FrancescaLisboa, @CristinaStern, and @Lgazarini
doi.org/10.1016/bs.irn.2024.…
Isabel Werle retweeted
🥇Isabel Werle @Isabeus_ , doutoranda no @bertogliolab, conquistou o prêmio de melhor pôster no Congresso da IBNS@IBNSconnect na categoria pós-graduando. Parabéns por mais essa conquista, Isabel! Agradecimentos à @IBROorg, @farmacoufsc, @ufsc e @CNPq_Oficial pelo apoio!
Thrilled to have had the opportunity to participate in my first @IBNSconnect meeting, where I learned from amazing people. Grateful to have won the Best Poster Presentation award for sharing my research. Thanks, @IBROorg for the travel award that made my participation possible!
Isabel Werle retweeted
We need robust behavioral assays for #psychedelic drug development.
In this new study, @Sam_C_Woodburn systematically determined psilocybin’s effect on fear extinction as a function of dose, timing of administration, and serotonin receptors 🍄🐁
biorxiv.org/content/10.1101/…
Isabel Werle retweeted
Very pleased to see this work officially published! More results coming, isn't that right, @Isabeus_ 😉!
bpspubs.onlinelibrary.wiley.…
Feliz em compartilhar essa matéria sobre nosso artigo mais recente @bertogliolab. Obrigada @PsyPost pela oportunidade!
Ayahuasca was found to speed up the extinction of fear memories in rats by affecting serotonin receptors in the brain. This effect, consistent across new and old memories, points to potential therapeutic uses for anxiety and trauma-related conditions. dlvr.it/T3pZkH
Isabel Werle retweeted
Temos uma bolsa de iniciação científica PIBIC/CNPq (R$ 700/mês) pra trabalho remoto na análise dos dados da Iniciativa Brasileira de Reprodutibilidade. A vaga é aberta para alunos de graduação em qualquer lugar do país. Detalhes e inscrições até 26/1 em forms.gle/D8zess8XXZ1WTWfN9
Isabel Werle retweeted
Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
sciencedirect.com/science/ar…
Isabel Werle retweeted
Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential
nature.com/articles/s41467-0…
