@bertogliolab

Catch the latest updates on aversive learning & memory, anxiety, fear, stress, and effects of psychedelics and cannabinoids from our lab and others!

 Florianopolis, SC, Brazil
Joined October 2010
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🆕Excited to share our latest review on psychedelics and fear extinction @Isabeus_ @FarmacoUFSC @fapesc @UFSC journals.sagepub.com/doi/10.…

Where is the sweet spot for psychedelic-enhanced fear extinction? An integrative quantitative...

Background: Individuals with anxiety and stress-related disorders frequently demonstrate impaired threat extinction. Although psilocybin, lysergic acid diethyla...

journals.sagepub.com
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Gi Signaling Does Not Differentiate Hallucinogenic from Nonhallucinogenic 5-HT2A Receptor Agonists pubs.acs.org/acncdm/article/…

Gi Signaling Does Not Differentiate Hallucinogenic from Nonhallucinogenic 5-HT2A Receptor Agonists

Abstract. A recent publication by Xu et al. suggests that Gi activation following 5-HT2AR stimulation differentiates hallucinogenic from nonhallucinogenic

pubs.acs.org
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Ketamine induces synaptic and monoaminergic remodeling in human iPSC-derived neurons nature.com/articles/s41398-0…

Ketamine induces synaptic and monoaminergic remodeling in human iPSC-derived neurons

Translational Psychiatry - Ketamine induces synaptic and monoaminergic remodeling in human iPSC-derived neurons

nature.com
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Subanesthetic ketamine modulates region-specific neural and endocrine responses to acute stress in rats sciencedirect.com/science/ar…
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Investigation of the pharmacological and circuit basis for psychedelic drug effects on interval timing in mice doi.org/10.1007/s00213-026-0…

Investigation of the pharmacological and circuit basis for psychedelic drug effects on interval...

Psychopharmacology - Classical psychedelic drugs such as the tryptamine psilocybin can alter temporal perception. Previously, the phenylethylamine psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI),...

link.springer.com
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Bertoglio lab (FMC/UFSC) retweeted
Ministra da Luta de Classes
@BellatrixMarla18h
O Flávio não responde nada! Só ataca com dados mirabolantes da imprensa! Responde a pergunta: por que foi contra as mulheres quando era deputado?? #RespondeOLulaFlavio
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Bertoglio lab (FMC/UFSC) retweeted
Vee@GiljuSayu18h
Lula: “Explica os 134 milhões do Vorcaro” Flavio: “Ja ouviu falar de Jair Bolsonaro? Foi o melhor presidente do Brasil” #RespondeOLulaFlavio #FlavioSocioDoCareca #LULAVAIVENCER #AtoPelaDemocracia
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Ketamine administration reduced conditioned defensive behaviour and upregulated protein expression associated with neuroplasticity in a planarian model of aversive memory reactivation doi.org/10.1016/j.pnpbp.2026…
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Stage- and context-dependent modulation of fear memory by oxytocin: neurobiological mechanisms and implications for PTSD doi.org/10.1016/j.neubiorev.…
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Cannabidiol attenuates behavioral impairments and deficits in parvalbumin interneurons and their perineuronal nets induced by adolescent stress in adult mice doi.org/10.1016/j.pnpbp.2026…
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Beyond psychedelic exceptionalism: how people combine meditation with psychoactive substances, and how this relates to well-being doi.org/10.1007/s00213-026-0…

Beyond psychedelic exceptionalism: how people combine meditation with psychoactive substances, and...

Psychopharmacology - Combining meditation with psychoactive substances is often assumed to be a niche practice centred on classic psychedelics. We sought to broaden this narrative in two...

link.springer.com
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What goes up must comedown: prevalence rates, characteristics, and coping strategies concerning MDMA after effects doi.org/10.1007/s00213-026-0…
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5-HT1B receptors expressed on forebrain excitatory neurons mediate the post-acute anxiolytic response to psilocybin in mice doi.org/10.1007/s00213-026-0…

Serotonin 1B receptors expressed on forebrain excitatory neurons mediate the post-acute anxiolytic...

Psychopharmacology - Psilocybin can produce rapid and sustained antidepressant-like and anxiolytic effects, yet the receptor and circuit mechanisms underlying these behavioral changes remain...

link.springer.com
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The endocannabinoid system and the ageing brain nature.com/articles/s41583-0…

The endocannabinoid system and the ageing brain

Nature Reviews Neuroscience - Age-related changes in endocannabinoid system (ECS) activity might contribute to the decline in cognitive function observed during ageing. In this review, Andreas...

nature.com
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An aging-sensitive secreted phospholipase confers neuroprotection and cognitive resilience nature.com/articles/s41593-0…

An aging-sensitive secreted phospholipase confers neuroprotection and cognitive resilience

Nature Neuroscience - This study identifies a secreted phospholipase in the hippocampal dentate gyrus that mediates an aging-sensitive compensatory mechanism promoting cognitive resilience and...

nature.com
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