@IsaacChiuLab

A group of scientists studying neuroimmune interactions in the context of infection, pain, itch and neurodegeneration @harvardmed

 Boston, MA
chiulab.med.harvard.edu/
Joined May 2022
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  • Following90
  • Followers1.2K
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Looking forward to hearing from this amazing line up of scientists, especially Chiu lab postdoc @Liwen_Deng811! She has an exciting story about microbe interactions with itch neurons, and is going on the job market soon!
Michael G. Constantinides@Immuno_Mike9 Sep 2024
Hear from a talented lineup of immunologists next Wednesday, Sept 18 featuring @zurisullivan, @alexwellsies, @DjenetBousbaine, @ValeriaMReyes, @CicaCanesso, @ScientistBecs, @Liwen_Deng811, & @NZanluqui. Register: bit.ly/ScrippsLeaders
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We wish Kim and Daping good luck as they begin new positions and progress in their scientific careers! Kim has accepted a staff scientist role at Mayo Clinic and Daping is starting up his own lab at the Institute of Neurosciences, CAS Shanghai. We will miss you both!
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The Chiu Lab is bringing in the new year with good food and even better company! Lots to celebrate from the past year and plenty to look forward to in the new year. Cheers!
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🚨PAPER ALERT🚨 We're excited to share @Liwen_Deng811 work below! Congrats to Liwen, Samantha, and all other Co-authors! cell.com/cell/fulltext/S0092…

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis

Itch evokes a desire to scratch, but the link between microbes and itch was unclear. Staphylococcus aureus, a bacterial pathogen, secretes a protease V8 that activates PAR1 expressed on neurons to...

cell.com
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Congrats to our two wonderful Research Assistants, Samantha and Matthew on participating in the Second Annual Synaptogenesis RA Symposium! Thanks @HMS_Neuro for hosting such a great event!
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Scientist during the week, artist on the weekend 🎨🧪
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A great summary of our recent GSDME work by Zhou et al., @dukenus, and a useful outline of therapeutic modalities that could target this protein in #neuro @himanishbasu @IsaacChiuLab🧠 linkinghub.elsevier.com/retr…
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Congrats on the Chiu labs most recent PhD, @dylanvneel!!! 🎉🎉🎉 Your contributions to the lab will be missed but we wish you luck finishing up medical degree!
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Even though this was last month, we're still thinking about how much fun we had at the Immunology retreat! Kudos for Samantha and Matt for presenting excellent posters! Looking forward to next year!
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Congrats to @EnnerfeltHannah on her 1st corresponding author paper. CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer’s disease mouse model | PNAS pnas.org/doi/10.1073/pnas.23… @PNASNews #AlzheimersDisease
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Thrilled to announce I received the notice of award for my F32 from @NIDDKgov! Grateful for all of the support and guidance from my mentor @IsaacChiuLab and Co-mentor Christophe Benoist.
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How Bacteria Invade the Brain @harvardmed News animation showing how bacteria hijack crosstalk between nerve and immune cells to cause meningitis. Animation illustrates recent research by the lab of @IsaacMChiu @IsaacChiuLab hms.harvard.edu/news-events/…

Animation: How Bacteria Invade the Brain

Research shows bacteria hijack crosstalk between nerve and immune cells to cause meningitis

hms.harvard.edu
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New Insights into ALS- @harvardmed News on a new study from @IsaacChiuLab, Judy Lieberman, and colleagues, co-first authors @dylanvneel & @himanishbasu, suggesting that inflammatory proteins in innate immune system may damage neurons and could lead to ALS hms.harvard.edu/news/new-ins…

New Insights into ALS

Study suggests inflammatory proteins in innate immune system may damage neurons, lead to ALS

hms.harvard.edu
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Some collabs are just fun - this is one! Congrats @dylanvneel and @himanishbasu! Bonus!! Check out this insane video included:
Chiu Lab@IsaacChiuLab13 Mar 2023
Excited to share our work out today in @NeuroCellPress ! Congrats to @dylanvneel @himanishbasu and co-authors! We find the innate immune protein GSDME drives mito-damage and axon loss in neurons, and GSDME KO is protective in models of #ALS urldefense.proofpoint.com/v2…
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Coverage of our work from @harvardmed & @BostonChildrens ! New Insights into ALS hms.harvard.edu/news/new-ins…

New Insights into ALS

Study suggests inflammatory proteins in innate immune system may damage neurons, lead to ALS

hms.harvard.edu
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Excited to share our work out today in @NeuroCellPress ! Congrats to @dylanvneel @himanishbasu and co-authors! We find the innate immune protein GSDME drives mito-damage and axon loss in neurons, and GSDME KO is protective in models of #ALS urldefense.proofpoint.com/v2…
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Thank you to terrific collaborators @LeeRubinLab @YoungPearseLab @alicechenp @TNRLab @rmgiadone and the Twitterless Judy Lieberman, Brian Wainger, Len Petrucelli, Yong-Jie Zhang and Clotilde Lagier-Tourenne. From our lab: Georgia Gunner, Matt Bergstresser and Haeji Chung.
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Amazing new study from the Liberles lab published in @Nature, showing a role of peripheral sensory neurons in transducing influenza-induced sickness. nature.com/articles/s41586-0…
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Was great sharing my work yesterday with the #celldeath community @harvardmed. Thanks to @j_ubellacker and @CellDeathLab for the generous invitation. Encourage anyone interested in the cell and molecular biology of disease to attend next month!
Kristopher Sarosiek@CellDeathLab21 Feb 2023
The Boston Cell Death Initiative is excited to re-launch our seminars after a COVID hiatus. Join us for #ferroptosis & #pyroptosis talks from Whitney Henry (@weinberglab @WhiteheadInst @MIT) & @dylanvneel (@IsaacChiuLab @harvardmed) on March 6th at 4PM. hsph.harvard.edu/cell-death-…
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Congrats to @felipe_pinh0 and co-authors on our recent work, now out in @Nature! We show that pathogens talk directly to nociceptor neurons to hijack CGRP-RAMP1 signaling, and alter the course of bacterial meningitis. Well done everyone! nature.com/articles/s41586-0…
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Thank you to co-authors/collaborators @Liwen_Deng811, @dylanvneel @himanishbasu, @stevens1lab @KdoranLab, @rag1_rag2, @DapingYang88, @scarneironasc, Alec Walker, Dan Levy, Kathleen He, Samantha Choi
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Interested students and post-docs should check out the @NeurobiomeLab @WUSTLmed. Felipe is a rising star in #science and will continue making many important discoveries 🌟 🧫 🦠 #neuroimmunology #pain #infection #meningitis
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