A group of scientists studying neuroimmune interactions in the context of infection, pain, itch and neurodegeneration @harvardmed

Boston, MA
Joined May 2022
A great summary of our recent GSDME work by Zhou et al., @dukenus, and a useful outline of therapeutic modalities that could target this protein in #neuro @himanishbasu @IsaacChiuLab🧠 linkinghub.elsevier.com/retr…
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Congrats to @EnnerfeltHannah on her 1st corresponding author paper. CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer’s disease mouse model | PNAS pnas.org/doi/10.1073/pnas.23… @PNASNews #AlzheimersDisease
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Thrilled to announce I received the notice of award for my F32 from @NIDDKgov! Grateful for all of the support and guidance from my mentor @IsaacChiuLab and Co-mentor Christophe Benoist.
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How Bacteria Invade the Brain @harvardmed News animation showing how bacteria hijack crosstalk between nerve and immune cells to cause meningitis. Animation illustrates recent research by the lab of @IsaacMChiu @IsaacChiuLab hms.harvard.edu/news-events/…
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New Insights into ALS- @harvardmed News on a new study from @IsaacChiuLab, Judy Lieberman, and colleagues, co-first authors @dylanvneel & @himanishbasu, suggesting that inflammatory proteins in innate immune system may damage neurons and could lead to ALS hms.harvard.edu/news/new-ins…
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Some collabs are just fun - this is one! Congrats @dylanvneel and @himanishbasu! Bonus!! Check out this insane video included:
Excited to share our work out today in @NeuroCellPress ! Congrats to @dylanvneel @himanishbasu and co-authors! We find the innate immune protein GSDME drives mito-damage and axon loss in neurons, and GSDME KO is protective in models of #ALS urldefense.proofpoint.com/v2…
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Amazing new study from the Liberles lab published in @Nature, showing a role of peripheral sensory neurons in transducing influenza-induced sickness. nature.com/articles/s41586-0…
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Was great sharing my work yesterday with the #celldeath community @harvardmed. Thanks to @j_ubellacker and @CellDeathLab for the generous invitation. Encourage anyone interested in the cell and molecular biology of disease to attend next month!
The Boston Cell Death Initiative is excited to re-launch our seminars after a COVID hiatus. Join us for #ferroptosis & #pyroptosis talks from Whitney Henry (@weinberglab @WhiteheadInst @MIT) & @dylanvneel (@IsaacChiuLab @harvardmed) on March 6th at 4PM. hsph.harvard.edu/cell-death-…
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The Boston Cell Death Initiative is excited to re-launch our seminars after a COVID hiatus. Join us for #ferroptosis & #pyroptosis talks from Whitney Henry (@weinberglab @WhiteheadInst @MIT) & @dylanvneel (@IsaacChiuLab @harvardmed) on March 6th at 4PM. hsph.harvard.edu/cell-death-…
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OBS #Neuroimmunology Seminars 📆 Thu, 2/2, 11:30 am ET /5:30 pm CET SPEAKER HIGHLIGHT 📌 @DapingYang88 - @IsaacChiuLab "Nociceptor neurons and Immunity" #openscience #neuroimmunology #nocireceptors #immunity
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So excited to see our goblet cell image get selected for the cover. We also prepared a cartoon one, which is inspired by the battle of Thermopylae.
Congratulations to @DapingYang88 and lab members on our recent work, now on the cover of @CellCellPress! Glad to have this work out and excited to continue studying how neurons regulate barrier function and #immunology in the #gut and other sites authors.elsevier.com/c/1fv-7…
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Checkout this latest @CellCellPress issue with the coolest cover from @IsaacChiuLab @DapingYang88 and thanks @BenJMarsland @Nicola_L_Harris for this nicely-written preview summarizing results both groups. Adding data to gut feelings: Cell cell.com/cell/fulltext/S0092…
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The gut is beautiful! Cover image from @DapingYang88 @IsaacChiuLab recent @CellCellPress paper showing nociceptors innervating goblet cells. Congratulations to Daping again for the fantastic story and beautiful image!
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Happy to share our new review about the interactions between nociceptors and microbes. Check it out on @PAINthejournal @Liwen_Deng811 @IsaacChiuLab #pain #microbes #neuroimmune journals.lww.com/pain/Fullte…
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🔬 New research from the @IsaacChiuLab shows that pain #neurons in the mouse gut regulate the presence of protective mucus under normal conditions, and stimulate intestinal cells to release more mucus during states of inflammation! hms.harvard.edu/news/study-f…
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So excited that our #Cell paper comes out! Thank you all coauthors! Here’s the free Access. Enjoy reading!
authors.elsevier.com/c/1fv-7…
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Dr. Isaac Chiu @IsaacMChiu @IsaacChiuLab, the curious, talented and humble scientist welcomed this dentist to his lab three years ago. Dr. Chiu gave a beautiful talk @IASPpain #IASP2022 and made us to think🧐🤔 if we could use bacterial toxins 🦠🦠to silence pain. @PainResForum
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Congrats to @larissasferrari @IsaacChiuLab Beautiful presentation on the assessment of CCL17 neutralization in different pain models at #IASP2022 @IASPpain
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Who wants to be a Harvard Professor? Calling all postdocs. I am running a search for a new junior faculty member. Specific area of biology is not specified--we are merely interested in smart people who want to change the world. Deadline November 1. nature.com/naturecareers/job…
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We have liftoff! Great overviews of the official launch of the iPSC Neurodegenerative Disease Initiative (iNDI). Large-scale, NIH-funded resource of genetically-engineered isogenic iPSC lines harboring neurodegeneration-related mutations. nia.nih.gov/news/new-web-por…
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