@ImpensLab

We study host-bacteria interactions using Listeria and MS-based Proteomics with a focus on Ubiquitin-like modifications (e.g. ISG15) and MHC complex peptides.

Ghent, Belgium.
Joined October 2021
🚀 Boosting bacterial immunopeptide discovery! Our bioinformatics workflow integrates 4 search engines with follow-up rescoring to enhance ID by 27%, maximizing the discovery of vaccine candidates. Applied to timsTOF/Thermo data🦠💉 @ImpensLab 🔗Read: pubs.acs.org/doi/full/10.102…
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Excited to share our latest MCP article uncovering > 6,000 MHC class I immunopeptides in Listeria-infected mice, including 12 Listeria peptides and a potent CD8+ T cell epitope. Many thanks to all co-authors for the excellent work! Read more at doi.org/10.1016/j.mcpro.2024…
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Impens Lab retweeted
👏Congratulations to @kkariko & @weissmanlab on becoming #NobelPrize laureates. A lifetime achievement celebrating their important research on #mRNA technology in vaccines. 🤔Did you know VIB, together with @VUBrussel, @ugent and participation of several international institutes helped establish the #BAXERNA consortium to further explore the potential of mRNA vaccines?
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We are looking for a #postdoc position in #immunopeptidomics @ VIB & UGent with proteomics/peptidomics expertise to develop novel antibacterial #vaccines, see jobso.id/g492. A warm call to proteomics postdocs to apply!
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Research on #Moyamoya disease @ImpensLab: "Rare diseases result from dysregulated, often yet unknown molecular pathways. Investigating these conditions can lead to groundbreaking fundamental discoveries while opening treatment options for the patients."
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We are very excited and extremely grateful to receive this #ERCCoG grant from @ERC_Research. It is a recognition for the whole team and we thank @VIB_CMB @ugent @ugent_fge @VIBLifeSciences @FWOVlaanderen and many others for their continuous support!
🎊 More wonderful @ERC_Research news! @ImpensLab has received an #ERC Consolidator grant for his research on #Moyamoya disease (#MMD). With this grant, the Impens Lab hopes to provide unprecedented insight into MMD-related immune responses! 👉 bit.ly/3RgnPD7
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Another wonderful story from the Radoshevich lab. A must-read (and watch!) for all Listeria and comet tail aficionados.
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Impens Lab retweeted
💉 Francis Impens and team (@ImpensLab @VIB_PRC @VIB_CMB) design an mRNA vaccine against Listeria and open the door for other antibacterial vaccines. bit.ly/3g89LwR
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Finally published! Thank you all co-authors for their priceless contribution! Here we designed mRNA vaccine formulations against Listeria using immunopeptidomics Looking forward to continue our efforts to tackle other intracellular bacterial pathogens tinyurl.com/vaccineListeria
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First day of the 4-day BePA Proteomics Summer School @ VIB starting with interesting talks on Proteomics applications and the DOs and DONTs of sample preparation 👉👉 bit.ly/3CELRCf #proteomics #tech #training #summerschool
Very happy to share our work on mRNA vaccine formulations against Listeria MS and immunopeptidomics hold great promise to uncover antigens for next-generation vaccines, especially for intracellular bacteria. Incredibly grateful to all co-authors for their dedication and efforts!
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