@HandeTopel
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Researcher | @DDA_Denmark postdoc fellow @Metabolcenter @koebenhavns_uni | Visiting Researcher @GenomicsUnit @UniSouthDenmark #KornfeldLab
Odense, Danmark
Joined December 2019
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Merhaba, bu çok uzun zamandır yapmak istediğim ve bir türlü gücümü toplayıp da başına oturup yazamadığım bir tweet zinciri.
Read our latest #research letter introducing a versatile gene delivery platform to study the soluble proteoforms of membrane proteins in #adipocytes — uncovering new layers of #metabolic communication.
#AdipocyteBiology #MetabolicResearch
#EctodomainShedding #GeneDelivery
EctoShed: A novel Gene Delivery Platform for Functional Analysis of Adipocyte-Shed Proteoforms biorxiv.org/content/10.1101/… #biorxiv_molbio
Hande Topel retweeted
Check out our paper now online at Cell Metabolism: Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein. Amazing work by Daniel, Jasmin, Christian, Peter, Oliver from @ravnskjaer_lab, and many more 🏆💐♥️
cell.com/cell-metabolism/ful…
Hande Topel retweeted
Postdocs from diverse fields joined our interactive workshop with @hfpconsulting to boost their leadership skills last week. Through real-life scenarios, they mastered communication, conflict resolution, and time management — tools for success in any career path 🤝
#DDEA
Hande Topel retweeted
🚀 Redefining Success in Science: Lessons from Luke Johnston's Journey
"Once you find the right project, no one will care about your publication record—they’ll care about what you can contribute,”
Read the full interview with @lwjohnst 👉 buff.ly/3MO3F1W
Hande Topel retweeted
Exciting postdoc opportunity on long read sequencing of human clinical material, in my group in Copenhagen job.jobnet.dk/CV/FindWork/De… @PostdocPhd @PostdocO
Hande Topel retweeted
Agreed?
ALT A quote that says "I want AI to do my dishes so that I can do art and writing, not for AI to do my art and writing so I can do laundry and dishes"
Have you spotted the luckiest co-supervisor / postdoc at the conference? Surrounded by these brilliant students and a 5-month-old!
Favorite conference so far!
@cphbat2017 #CPHBAT2024
Had a great first day at #CPHBAT2024! Fantastic talks and the chance to present and get input on my co-supervisor @HandeTopel and mine, and my colleague Nadia’s work on AOC3 targeting in #obesity. Feeling very lucky for being in such an inspiring scientific environment and team
Our paper is now online at @NatMetabolism! Check it out to learn more about the built-in break mechanism in BAT activation.
@sajjad_khani @DagmarWachten @Kornfeld_JanW – at Odense, Danmark
Online now! Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function dlvr.it/T6BlCz
Hande Topel retweeted
Extremely happy for my former colleague @sajjad_khani, @HandeTopel @DagmarWachten & @Kornfeld_JanW to see this work published @NatMetabolism now!
A novel rheostat to brown fat function🔥
nature.com/articles/s42255-0… – at Munich, Germany
Hande Topel retweeted
Thrilled that our huge team effort with @Kornfeld_JanW is out in @NatMetabolism 🥳 supported by @TRR_BATenergy A huge thank you to all collaborators! If you want to know how a truncated AC3 isoform regulates #BAT function, have a look here nature.com/articles/s42255-0…
Hande Topel retweeted
Accepting a round of applications for a week before shortlisting
The shortlist is too short at the moment :(
Inviting candidates with experience in hiPSC-based cardiac differentiation models/Genome engineering/ Ribo-seq/ Proteomics/ polysome profiling/ data analysis
Are you an RNA biologist or developmental biologist studying cardiac development? Join us at our new lab at the Vascular Research Center @UK_Frankfurt. We are expanding our team: Currently hiring 1 Postdoc and 2 PhD students to study mRNA translation @ERC_Research
Please RT🙏
Hande Topel retweeted
Extremely overwhelmed with this feeling of going back to my postdoc lab and feel HOME. Thank you for these two emotional and amazing days 🥹🥹🥹 see you around the world! @MPI_Metabolism
Hande Topel retweeted
How does mitochondria sense and control their glutathione levels? Our new work @ScienceMagazine by a fantastic student @YuyangLiu1996 describing a redox metabolite sensing mechanism for mitochondria. @RockefellerUniv @TheMarkFdn science.org/doi/10.1126/scie…
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IS THE SCIENTIFIC PUBLICATION, AS WE KNOW IT, DEAD?! 400 years ago, the first scientific publications were published. Whilst the science has progressed, the format, a publication in a journal, has not. We challenged the participants on the subject at this year's Postdoc Summit 👇
Hande Topel retweeted
Interested in working on primary #cilia signaling funded by @NSF @dfg_public, combining genetics, proteomics, optogenetics at @TamaraGenes @MickLab @DagmarWachten ? Apply now! Our labs have open calls for a #PhDposition and a technician. Please get in touch if you are interested!
Hande Topel retweeted
In this study, driven by @tcppham🔥we integrated diet-induced obesity Drosophila and mouse models, metabolomics studies, and a multitude of metabolic screening approaches and identify TNIK as a conserved regulator of glucose and lipid metabolism in obesity science.org/doi/10.1126/scia…
Our short data report presents in vitro evidence for the selective role of c-Met in extravasation of HCC cells through endothelial barrier into hepatocyte microenvironment. (1/3)
@AtabeyLab @BBAjournals
authors.elsevier.com/c/1hZUF…
In this experimental setup, we used a LOC device to establish a 3D microenvironment mimicking endothelial barrier and organ-specific cell type niches (hepatocytes, bone marrow fibroblasts, lung epithelia) to study extravasation and homing behaviour of HCC cells. (2/3)
Having the opportunity to report short but original experimental data timely through a peer-reviewed process is amazing.
Thanks @BBAjournals for enabling researchers to share their brief significant scientific observations as research letters. (3/3)
Hande Topel retweeted
📢 Our group is looking for a #postdoc 👩🔬🧑🔬 to help us unravel the molecular mechanism of #vascular adaptations in response to #obesity and #cancer. If you wish to join our dynamic and #international team apply here 👉 tiny.cc/Aarhus The call is closing on the 20. July.