Laboratory for Cellular Architecture | Studying how actin dynamics builds cell and tissue structures in health and disease | The Scripps Research Institute
La Jolla, San Diego
Joined March 2018
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- Following18
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Fowler Lab retweeted
Just uploaded my first post with @preLights ! Read to learn more about an awesome system developed by @AshToye_Bristol and @thebaumlab to study malaria parasite invasion. prelights.biologists.com/hig…
#UltimaThule or enculeating erythroblast? You decide.
Phone and confocal data courtesy of @RBNowak74
Fowler Lab retweeted
How changing labs after grad school revealed a catalytic function for an eye lens protein long thought to be chemically inert @jbiolchem bit.ly/2BBRZLU via @asbmb @EurekAlert
Fowler Lab retweeted
Our review article on the regulation of actin dynamics by tropomodulin 3 is now published! link.springer.com/article/10…
Fowler Lab retweeted
Today at 2pm ET: For the first time ever, two female scientists won the #NobelPrize for both physics and chemistry. We'll be chatting with one of the recipients @francesarnold on #SciFriLive! scifri.me/os1
Fowler Lab retweeted
Congratulations to Frances Arnold, George Smith, and Gregory Winter, whose Nobel-winning achievements have enabled such exciting science. Read some of their papers in JBC: bit.ly/2NgCNGw
Fowler Lab retweeted
ARP2/3 COMPLEX IN ACTION
Arp2/3 creates networks of branched actin filaments, and plays roles in endocytosis, membrane trafficking, cell motility, etc. But do not be fooled by the vast literature. We are only scratching the surface of how Arp2/3 functions in cells.
#CellBiology
Check out this very cheap TIRF scope! The site also has posts about other inexpensive/DIY lab equipment.
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Fowler Lab retweeted
SO MUCH EFFORT .....
SO LITTLE PROGRESS
Are you working a lot and not getting anywhere? This epithelial cell knows how you feel.
#CellBiology
Our work on myosin in red blood cells was recently featured in @TheScientistLLC ! the-scientist.com/the-litera…
Check out the original paper in @PNASNews here pnas.org/content/early/2018/…
Read Justin and Velia's review to learn everything you need to know about Tmod3!
My preprint has been published today in @PeerJPreprints peerj.com/preprints/27172 #Biochemistry #CellBiology #MolecularBiology
Happy Wednesday from the newest members of the Fowler lab - the giant podocyte, platelet, and red blood cells! Starting with the podocyte: 1,000,000x, 5,000,000x, 1,250,000x, and 750,000x actual size.
Today marks the end of summer intern season in the Fowler lab! We hosted two high school students and one undergrad who made significant progress in our RBC myosin and lens tropomyosin projects. Thanks @hightechhigh @ScrippsRTI and @SD_LSSI for making these internships possible.
Nominate your favorite female microscopists! There are only two in San Diego so far.
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Fowler Lab retweeted
We're looking for a postdoc synthetic/medicinal chemist to work with Jeff Kelly @scrippsresearch on hit-to-lead development of stabilizers of amyloid precursor proteins. Would suit a new PhD. Immediate start. Good facilities and resources, great weather. DM me. #chemjobs
Fowler Lab retweeted
CANCER ON THE MOVE
A #melanoma cell crawling in a culture dish sitting on a spinning disk confocal microscope.
#CellBiology #cancer #cancerresearch
Check out @ParrenoJustin 's paper on mechanical strain in the mouse eye lens in @MBoCjournal published online this week! Authors include Cathy Cheng and @RBNowak74 molbiolcell.org/doi/full/10.…
Yes! The human eye can detect so much more information from grayscale images. xitter.cf/MAG2ART/status/1021412…
DISPLAY DATA IN GRAYSCALE
Don't get me wrong, I do love color overlays of microscopy #data. However, try to show each grayscale channel when possible (especially in figures). When it comes to data, more is more.
Movie: crawling #cancer cell
#CellBiology