@ECSanderson

Lecturer in Medical Statistics. Research focuses on Mendelian randomization and instrumental variables.

 Bristol
Joined May 2011
  • Tweets414
  • Following223
  • Followers418
4Media
Eleanor Sanderson retweeted
Amanda Hughes@ammhughes20 Dec 2022
How much does a child's BMI affect their depression, anxiety, or ADHD symptoms? Not much, suggests our new research which accounts for family-level factors. Read it here: elifesciences.org/articles/7…. With @ECSanderson @nm_davies @laurahowe_epi @alexhavdahl @bristimtom @mrc_ieu

Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity...

It is unclear how much a child's BMI at age 8 affects their depressive and ADHD symptoms after family-level factors are accounted for, but a substantial impact on anxiety symptoms is unlikely.

elifesciences.org
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Eleanor Sanderson retweeted
JBMRPlus@JBMRPlus27 Oct 2022
Check out our new Editor’s Pick from @JBMRPlus Associate Editor Emma Clark @emcbristol! A Guide for Understanding and Designing Mendelian Randomization Studies in the Musculoskeletal Field @MRC_IEU @Brms_Research @BristolUni (1/6) doi.org/10.1002/jbm4.10675
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This Primer explains Mendelian randomization - from concepts to required conditions - and describes key applications and applying the technique to growing genomic datasets @MariaGlymour @mvholmes @MarcusMunafo @jeanv_morrison @chr1swallace go.nature.com/3x3IIJc
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Eleanor Sanderson retweeted
IJE@IntJEpidemiol16 Aug 2022
Interpretation of Mendelian randomization using a single measure of an exposure that varies over time doi.org/10.1093/ije/dyac136
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Eleanor Sanderson retweeted
Hannah Elliott@hannah_elliott22 Jul 2022
New paper assessing causality of DNA methylation associations with prevalent type 2 diabetes. Congratulations to @Dianajuvi89 for leading the work, very lucky to work with you! @carolinerelton @ECSanderson @ammegandchips @mrc_ieu #diabetes #MR medrxiv.org/cgi/content/shor…
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Mendelian randomization outlined by ⁦@ECSanderson⁩ at #Mendel200
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New preprint out! In it we propose a (simple!) solution to the bias caused in Mendelian randomization from covariate adjusted GWAS statistics doi.org/10.1101/2022.07.19.2… Led by PhD student Joe Gilbody, also thanks to @MCarol_Borges and @mendel_random!
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Eleanor Sanderson retweeted
MRC IEU@mrc_ieu19 Jul 2022
This is happening tomorrow! Thank you to all our speakers, helpers and all who've registered to join us (not too late if you want to join us online!). See you tomorrow! #Mendel200
MRC IEU@mrc_ieu11 Jul 2022
Still time to register for conference celebrating 200th birthday of Gregor Mendel. Join us in Bristol (in what will be one of the last chances to visit iconic @BristolZooGdns) or as one of 100s of ppl worldwide joining for free online. Find out more here: bristol.ac.uk/integrative-ep…
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Our new paper on using Multivariable MR with multiple measures of a single exposure was published today. In it we discuss the approach, the assumptions required and interpretation of the results. doi.org/10.1371/journal.pgen…

Estimation of causal effects of a time-varying exposure at multiple time points through multivari...

Author summary Mendelian Randomisation (MR) can be used to estimate whether a potential exposure has a causal effect on an outcome in the presence of a third (unobserved) variable that affects both...

journals.plos.org
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Thanks to everyone involved with this! @mendel_random @iTomRichardson @bristimtom and Kate Tilling!
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Eleanor Sanderson retweeted
MR_lit@Mendelian_lit19 Jul 2022
Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization dlvr.it/SV6bJ6
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Eleanor Sanderson retweeted
MR_lit@Mendelian_lit18 Jul 2022
Interpretation of Mendelian randomization using a single measure of an exposure that varies over time dlvr.it/SV5x4N
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Eleanor Sanderson retweeted
Joshua Bell@joshuaa_bell7 Jul 2022
Finally: causal estimates for adiposity & metabolomic traits at scale! Pleased to share the first large-scale comparison of conventional vs MR approaches in UK Biobank in @LancetRH_Europe sciencedirect.com/science/ar… Key takeaways:
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Eleanor Sanderson retweeted
Caroline Bull@caroline_bull6 Jul 2022
Our preprint “Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study” is now available: medrxiv.org/content/10.1101/…

Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian...

Background Observational studies have linked childhood obesity with elevated risk of colorectal cancer, however, it is unclear if this association is causal or independent from the effects of obesity...

medrxiv.org
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Excited to thumb through an actual hard copy of the book “Combining Human Genetics and Causal Inference to Understand Human Disease and Development” edited with @BeckyRichmond90 and Jean-Baptiste Pingault, a thread on what it contains /cont
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Eleanor Sanderson retweeted
MRC IEU@mrc_ieu27 Jun 2022
See the programme for our upcoming #Mendel200 conference to celebrate the bicentenary of Gregor Mendel. A great line up of speakers and topics. Join us online (free) or in person in Bristol, UK (small, subsidised price) bristol.ac.uk/integrative-ep…
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Eleanor Sanderson retweeted
MRC IEU@mrc_ieu22 Jun 2022
From pea plants to better understanding of public health ... our upcoming conference celebrates the 200th birthday of Gregor Mendel, his legacy and the range of research his work has inspired. Join us in person in Bristol or online on 20-21 July #Mendel200 bristol.ac.uk/integrative-ep…
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A limited number of in-person places now available at the “Mendel @ 200” meeting 20-21st July. shop.bris.ac.uk/conferences-…
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Eleanor Sanderson retweeted
Sarah Lewis@ProfSarahJLewis29 Apr 2022
**Funded PhD studentship at University of Bristol - to develop methods for applying Mendelian randomization in diverse populations and to apply these to identify risk factors for gallbladder cancer findaphd.com/phds/project/ph…

PhD Opportunity – Exploring the role of ancestry in Mendelian randomization studies and applying...

PhD Project - PhD Opportunity – Exploring the role of ancestry in Mendelian randomization studies and applying these findings to identify risk factors for gallbladder cancer at University of Bristol,...

findaphd.com
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