Engineering viral vectors for gene therapy @stanleycenter @broadinstitute
Cambridge, MA
Joined February 2019
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DevermanLab retweeted
📣🎉New pooled library! This screening library from George Church's lab contains all possible single codon substitutions, deletions, and insertions in the AAV2 cap gene.
hubs.la/Q022s6pR0
DevermanLab retweeted
iCAP-BI-28-KanR
Depositor: @DevermanLab
Purpose: RepCap for AAV production
addgene.org/203532/
DevermanLab retweeted
Early-career scientists: We want to fund your pilot studies in #genetherapy & #celltherapy!
ASGCT Members can apply for one of six $100,000 #CareerDevelopment awards by Aug. 1. Learn more and apply today! bit.ly/3w8vp6m
DevermanLab retweeted
Excited to introduce @DevermanLab machine learning guided platform that simultaneously optimizes multiple traits in AAV capsids valuable to gene therapy. #ASGCT22 May 19, 11:45am
DevermanLab retweeted
Results from a phase 1 clinical trial published in @NatureMedicine show that a broadly neutralizing, HIV-specific antibody is durably expressed in vivo from a viral vector, highlighting an alternate approach for the delivery of antibodies in humans. go.nature.com/3EsYyiJ
DevermanLab retweeted
Looking for talented RAs to join our lab and collaborative Neuroimmune project …Pls RT
Research Associate II, Stem Cell Models with @stevens1lab
Broad Institute of MIT and Harvard, Cambridge, MA, USA
jobrxiv.org/job/broad-instit…
#ScienceJobs
DevermanLab retweeted
Put this on your RADARS: our latest work on Reprogrammable ADAR Sensors for cell type targeting
A team effort by Chen lab members Jeremy Koob, @dawnchenx, & Yifan Zhang in collaboration with @idmjky, @RohanKrajeski, @jgooten, @omarabudayyeh, & AbuGoot lab
biorxiv.org/content/10.1101/…
DevermanLab retweeted
Today is covidcg.org's 1-year anniversary 🎉🎋🥳🎂
We have just released a new Lineage Reports feature on the site to help users quickly find out how the different SARS-CoV-2 variants of concern/interest are related to each other and which mutations they carry.
DevermanLab retweeted
I swear I'm sick of posting about the lab-leak stuff, but it seems very warped that a bunch of prominent scientists are saying we shouldn't investigate the claims for reasons that have little to do with science and lots to do with politics.
nature.com/articles/d41586-0…
DevermanLab retweeted
As scientists with relevant expertise, we agree with @WHO @DrTedros, US & 13 other countries, & EU that greater clarity about the #OriginsofCOVID is necessary and feasible to achieve. We must take hypotheses about natural & laboratory spillovers seriously.
science.sciencemag.org/conte…
DevermanLab retweeted
Version 2 of covidcg.org is up! New data selection interface, now able to handle all 733,480+ SARS2 genomes from GISAID.
Please send us your feedback and help us to debug the site!
DevermanLab retweeted
Andddddddd...it re-begins >>> Moderna Announces it has Shipped Variant-Specific Vaccine Candidate, mRNA-1273.351, to NIH for Clinical Study
businesswire.com/news/home/2…
DevermanLab retweeted
Surreal. By infecting FDA & CDC with science-ignorant politics, the White House has kneecapped our nation’s most important public health defenses during a pandemic that has already killed more than half the Americans lost in WWII. Vaccines are useless without our trust in them.
Breaking News: The White House has refused to accept proposed new FDA guidelines that could delay an emergency vaccine approval until after the election. nyti.ms/30zcx3q
DevermanLab retweeted
As neuroscientist David Anderson sat with his wife in restaurant in 2001, he explained his frustration in accessing brain gene expression data. He told her the field needed an institute to take an industrial scale approach to creating a gene expression atlas & openly share it 1/2
DevermanLab retweeted
In a new study (biorxiv.org/content/10.1101/…), we have completely mapped mutations to #SARSCoV2 that escape human antibodies, and shown that these "escape maps" predict how virus evolves under antibody pressure & inform design of escape-resistant antibody cocktails. (1/12)
DevermanLab retweeted
Take a look inside healthy human cells with the Visual Guide to Human Cells developed by our Allen Institute for Cell Science. The #openscience resource is publicly available to support research worldwide. #distancelearning
DevermanLab retweeted
With ~1M covid-19 cases now confirmed on the continent, @pasteurMG in Madagascar joins growing list of African countries sequencing and releasing #SARSCoV2 WGS
Sequences available @GISAID typed with PANGOLIN
@AAS_AESA @Afroscientist @AfricanScI @AASciences
DevermanLab retweeted
Instead of spending weeks preparing and titering your #AAV, let us do this for you! Our Made on Request AAV service will be available for AAV plasmids in our repository. hubs.ly/H0s5g710
DevermanLab retweeted
We report the use of base editors in vivo to correct a recessive genetic deafness in postnatal mice, with restoration of hair cell sensory transduction and partial improvement of auditory function following a single injection of base editor AAVs. (1/2)
drive.google.com/file/d/1ERQ…
DevermanLab retweeted
Blood type may correlate with COVID-19 severity, potentially in connection to blood clotting or inflammation factors. medrxiv.org/content/10.1101/…