At the interface between biology and computer science, we seek to better understand evolutionary and functional relationships between genes, genomes & species.
Lausanne, Switzerland
Joined October 2013
- Tweets238
- Following34
- Followers554
- Likes39
Dessimoz Lab retweeted
FastOMA is out now in Nature Methods 🎉: nature.com/articles/s41592-0… A new orthology inference algorithm that scales linearly and is highly accurate. FastOMA can process all >2000 eukaryotic UniProt ref proteomes <24 hours 🚀. Try it out at github.com/DessimozLab/fasto…
Dessimoz Lab retweeted
From @SinaMajidian, @DessimozLab and colleagues, FastOMA achieves fast and accurate orthology inference, with linear scalability.
nature.com/articles/s41592-0…
Dessimoz Lab retweeted
OMAnnotator: a novel approach to building an annotated consensus genome sequence
doi.org/10.1101/2024.12.04.6…
Automatic identification and annotation of MYB gene family members in plants
doi.org/10.1101/2021.10.16.4…
Dessimoz Lab retweeted
In this exciting new preprint, Warwick Vesztrocy et al use Bgee to show that "the most diverged orthologues display the greatest change in gene expression, thus suggesting that they have a greater functional divergence"
biorxiv.org/content/10.1101/…
Dessimoz Lab retweeted
Exploring gene duplications! Our study reveals how duplicated genes diverge in function using structural and expression analysis across 36 species. Check out our paper: biorxiv.org/content/10.1101/…
Thanks to @the_alexwv, @Gloveface, Paul Thomas, @cdessimoz
#Genomics #Evolution
Dessimoz Lab retweeted
Session 24: OMA/OMArk is starting now!
To join in the session, jump over to our discord at: discord.gg/gF73fCF4
Or you can join in on the YouTube stream at: youtube.com/@thebiodiversity…
@SinaMajidian @OMABrowser
Dessimoz Lab retweeted
Many interesting discussions at the #ISMB2024 poster sessions. Thanks to everyone who stopped by our poster and to #ISCB and @DessimozLab for the opportunity!
Dessimoz Lab retweeted
nature.com/articles/s41559-0…
Have a look at the article I reposted by @BallouxFrancois, @cedriccstan and @LucyvanDorp if you're interested in viruses and their evolutionary signature when jump hosts. I had the pleasure of writing a news and views piece about this work with @cdessimoz
Dessimoz Lab retweeted
Quality assessment of gene repertoire annotations with OMArk go.nature.com/4bH5OaF
Dessimoz Lab retweeted
📢 Glad to share our piece 'AI and the democratization of knowledge' @ScientificData. Data is the new oil—ripe for reuse. But what does it take to reuse? it's about making data interpretable by all, including AI, the ultimate non-specialist! #OpenScience nature.com/articles/s41597-0…
Dessimoz Lab retweeted
📢CALL FOR ABSTRACTS📢
🌟Abstract submission is now open for the Quest for Orthologs meeting #QFO8 which will be held at the University of Quebec in Montreal, Canada on July 17-18!
More info at event.fourwaves.com/qfo8
Deadline: April 26.
Dessimoz Lab retweeted
How to evaluate the quality of a genome annotation? Introducing #OMArk, a groundbreaking tool by SIB’s @Why_Nevers & @Dessimozlab and part of the SIB Resource #SwissOrthology, now featured in @NatureBiotech: nature.com/articles/s41587-0…
Dessimoz Lab retweeted
Our OMArk paper is finally out at @NatureBiotech! I am excited to share the final results of our work with @Gloveface @cdessimoz @VictorRossier @DessimozLab. OMArk is a one-stop shop for eukaryotic genome annotation assessment. Link : nature.com/articles/s41587-0… (🧵)
Dessimoz Lab retweeted
Join @DavidDylus in his #insilicotalks, unveiling Read2Tree - an innovative tool for swift phylogenetic tree inference from raw sequencing reads. Don't miss this if you're into comparative genomics, biodiversity or pathogen surveillance! #Phylogenetics tinyurl.com/yzbw9nbb
Dessimoz Lab retweeted
💡 Why choose OMA? Unique in its comprehensive orthology analysis, OMA offers unparalleled depth in prokaryotic & eukaryotic coverage, ancestral genome insights, and a suite of specialized tools. A one-stop solution for comparative genomics! #Orthology #OMAdvantage #OMAUpdate2024
Dessimoz Lab retweeted
🚀 Exciting news from the OMA team! Our 2024 update brings a host of improvements to our orthology knowledgebase. Stay tuned for a series of highlights! #OMAUpdate2024 #Genomics #Bioinformatics academic.oup.com/nar/advance…
Dessimoz Lab retweeted
I will be giving a talk on "Computational comparative genomics in the era of biogenome projects" at the University of Zurich, Department of Systematic and Evolutionary Botany.
Monday Nov 6, 16:00; Botanical Garden.
evolution.uzh.ch/en/events/o…
Dessimoz Lab retweeted
Our review on Genomic variant benchmarks is now out in @GenomeBiology: doi.org/10.1186/s13059-023-0…
We surveyed the Genome in a Bottle (GIAB) datasets (HG002-HG007), challenging medically relevant genes benchmark and many others.
@MedhatMahmoud_ @sedlazeck @D_Agustinho @infoecho
Dessimoz Lab retweeted
So excited that Dave’s amazing work is out: phylogenetic trees inferred from 3D structures do well and even outperform trees inferred from sequences! We were first incredulous but we’ve replicated the result using 2 quality indicators and multiple datasets & it seems to hold. 🧵
In a post #AlphaFold world, we can use protein structures in ways we never could before. Can we build phylogenies with them? Are they any good? Yes! Foldtree (biorxiv.org/content/10.1101/…) surpasses traditional sequence-based methods, even for closely related proteins.👇
Dessimoz Lab retweeted
📢 Want to Dive Deeper into the story behind the paper? Check Out the Blog Post! 📢 (lab.dessimoz.org/blog/2023/0…)
Foldtree was motivated by our work with deep phylogenies. These families of structural homologs had almost no sequence homology! How can we peer beyond the #TwilightZone?