New preprint analysing microbial signatures of Hospital-Acquired Pneumonia (HAP). HAP is a major cause of morbidity / mortality, yet it remains poorly defined microbiologically. We profiled the respiratory microbiomes of 250 HAP patients in the UK. Metagenomic sequencing detects putative pathogens in a significant number of PCR- and culture-negative samples, suggesting that conventional diagnostics underestimates the diversity and prevalence of HAP-associated microbes. 1/ Link to the study: biorxiv.org/content/10.1101/…