Scientist @itqbunl, working on disordered proteins and related challenges. PI of the Dynamic Structural Biology Lab aka Cordeiro Lab
Lisbon metropolitan area
Joined August 2015
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Tiago Cordeiro retweeted
#ITQBNOVA’s Open Day is back! 🧪✨
Explore our science with lab visits, talks, experiments, a scientific escape room and more!
📅 March 15 (Sat), 10am-5pm
🎟️ Free entry
Visit us and bring your family and friends!
Stay tuned for details.
@OeirasValley @NOVAunl
Tiago Cordeiro retweeted
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling biorxiv.org/content/10.1101/…
🚨 New preprint alert! 🚨 We uncover key aspects of how the #SARSCoV2 nucleocapsid protein self-assembles and undergoes LLPS—critical for viral behavior. Using #SAXS and #NMR, we reveal how disordered regions drive complex formation. Explore the details: biorxiv.org/content/10.1101/…
As someone who works in protein chemistry and structure, I’m thrilled to see the 2024 #NobelPrize in Chemistry awarded to David Baker, Demis Hassabis & John Jumper. Their work is transforming the field. Congrats to all! #ProteinChemistry #NobelPrize2024
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Tiago Cordeiro retweeted
Don't miss the opportunity to participate in such a great event for peptide chemists: the XIX Iberian Peptide Meeting in Santiago de Compostela.
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Tiago Cordeiro retweeted
Boy: Do not try and bend the protein. That's impossible. Instead... only try to realize the truth.
Neo: What truth?
Boy: There is no protein structure.
Neo: There is no protein structure?
Boy: Then you'll see, that it is not the protein that bends, it is only yourself.
Tiago Cordeiro retweeted
Get your applications in before Oct 1st
events.au.dk/biomolecular-co…
Would you see your name in this list of illustrious speakers?
Then we need your abstract before October 1st! We will close the abstract submission and select attendees for our wonderful meeting on biomolecular condensates on this date.
events.au.dk/biomolecular-co…
Tiago Cordeiro retweeted
Bacteria that turn water into ice❄️ 🔬
Pseudomonas syringae contains special surface proteins that act like scaffolds for ice nucleation!
#science #research #microbiology #biochemistry
Excited to share that @CordeiroLab presented our latest research at #IBSBC2024! A great opportunity to showcase our work @itqbnova and connect with fellow scientists and friends.
Tiago Cordeiro retweeted
We were incredibly disappointed with the lack of code or executable accompanying the publication of AF3 in @Nature . This contradicts scientific principles of the ability to evaluate, use, and build upon existing work. zenodo.org/records/11179894
Tiago Cordeiro retweeted
Summer Science @itqbnova is waiting for you! ☀️🧪
If you're an undergraduate student, from July 15-19th you'll get the chance to develop a lab project & take part in our social activities. 🌊
Apply by June 10th: shorturl.at/iqKWY .
@NOVAunl @OeirasValley
Tiago Cordeiro retweeted
No #DiaInternacionalDaMulher queria partilhar um artigo que escrevi há dias sobre a Ciência e as Cientistas em Portugal!
🎉 Exciting news! Our paper, "The Pathogen-Encoded Signaling Receptor Tir Exploits Host-Like Intrinsic Disorder for Infection" is officially published! @CommsBio,📚 Grateful for the collaboration and hard work of all involved. Read it here: doi.org/10.1038/s42003-024-0…
3/3 In eukaryotic cells, protein disorder is critical for signaling and regulation. Although intrinsically #disorderedproteins (IDPs) are a small fraction of typical bacterial proteomes, Tir helps us make the case that IDPs have a critical role at the host-bacteria interface.
2/3 Using various state-of-the-art biophysical methods (#SAXS, #NMR #microscopy), we show that Tir, a bacterial effector, exploits host-like disorder to rewire cellular processes via dimerization, lipid binding, and phosphorylation, revealing a versatile strategy for infection.
1/3 Have you ever wondered how pathogens hijack the host? 🦠 In our latest research, conducted in collaboration with @itqbnova, @LeibnizFMP, @NetBioinfoMRS, and @TheFrankelLab, we delve into the fascinating world of host-pathogen interactions.
Tiago Cordeiro retweeted
Happy to share the publication of our paper in @Nature
Conformational ensembles of the human intrinsically disordered proteome
Work led by @GiulioTesei and @AnnaIdaTrolle. I'll post more later, but for now here is a link:
nature.com/articles/s41586-0…
and a short movie about the work
Tiago Cordeiro retweeted
I just read a paper where the authors show how structural biases in IDP ensembles found in vitro are recapitulated inside human-derived cells, you should check it out @shaharsu ! nature.com/articles/s41594-0…
Congratulations to Guillem Hernandez Gras on the successful completion of his PhD in #MolecularBiosciences @itqbnova! 🎓👏 It's been a privilege to supervise his impactful research on 'Structure and Dynamics of Pathogenic Scaffold Proteins.'
Congrats to Guillem Hernandez Gras for his PhD in #Molecular Biosciences! 🎓👏
His #research, “Structure and Dynamics of Pathogenic Scaffold Proteins”, was supervised by #ITQBNOVA researcher Tiago Cordeiro.
@CordeiroLab @NOVAunl @OeirasValley
#TeamNOVA #MolBioS
