@ColnotLab

We study the biology of stem/progenitor cells in musculoskeletal development, regeneration and diseases.

 France
colnotlab.com/
Joined April 2021
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  • Following134
  • Followers239
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We are recruiting 2 postdoctoral researchers in biological and bio-informatics analyses to study skeletal stem/progenitor cells in bone development, regeneration and diseases. #inserm #upec #imrb
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ColnotLab retweeted
ColnotLab@ColnotLab30 Sep 2024
Our new study is out today in BoneResearch @SpringerNature entitled "Multimodal analyses of immune cells during bone repair identify macrophages as a therapeutic target in musculoskeletal trauma". 馃憠 rdcu.be/dVqVp
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Today I was honored to present with Stavroula Kousteni the Meet-the-Professor session on Stem Cells ASBMR Task Force Report @ASBMR #ASBMR2024 Thanks to all the participants for a stimulating discussion
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Important discussions related to stem cells at the ASBMR meeting this morning. @ASBMR2024
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This coordinated process is disrupted in musculoskeletal trauma leading to fibrosis and impaired healing. Modulating macrophage function decreased fibrosis and enhanced bone repair, revealing macrophages as a potential therapeutic target to treat trauma-associated fibrosis.
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@Inserm @UPECactus @IMRB_Mondor @yasminehachemi1 @SimonPerrin15 @Maria_Etell @AnaisJulien15 @ChristianGoritz Funding sources: @NIH_NIAMS @AgenceRecherche #BoneRepair #Immunology #SkeletalStemCells #MusculoskeletalTrauma #ScienceDiscovery
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We report an immune cell atlas of bone regeneration. Using single-nucleus transcriptomics, we uncovered parallel inflammatory responses of macrophages and skeletal stem progenitor cells in the early stages of bone healing.
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Our new study is out today in BoneResearch @SpringerNature entitled "Multimodal analyses of immune cells during bone repair identify macrophages as a therapeutic target in musculoskeletal trauma". 馃憠 rdcu.be/dVqVp
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Our latest publication is out in聽@ScienceTM. This study from @SimonPerrin15 and co-authors investigated a severe form of bone repair defect and found a very unexpected mechanism involving Schwann cells!
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This work opens new therapeutic perspectives for patients with CPT. It also provides exciting new concepts on the role of the periosteum and Schwann cells in bone healing and fibrous nonunion.
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We would like to thank everyone involved in this study @Inserm @IMRB_Mondor @UPECactus @InstitutImagine and our funding support @AgenceRecherche @DeptofDefense @NIH_NIAMS @ANR_FRANCE @OTCFoundation
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A postdoctoral position in musculoskeletal regeneration and stem cells is open in @ColnotLab #imrb #inserm #upec We look forward to receiving applications for this project integrating functional in vivo analyses, microscopy and single cell transcriptomics
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Very excited to start 2024 by sharing our new study from @colnotlab just out in @Elife In this study, we created a cell atlas of the periosteum and the fracture environment from 馃悂 to unravel the differentiation trajectories of skeletal stem/progenitor cells during bone repair馃憞
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F茅licitations 脿 @SimonPerrin15 qui a re莽u le Prix de l'Universit茅 2023 @valdemarne_94 pour sa th猫se de doctorat r茅alis茅e @IMRB @UPECactus et @univ_paris_cite et qui a port茅 sur le r么le du p茅rioste dans la r茅g茅n茅ration osseuse et la pseudarthrose cong茅nitale de jambe.
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Congratulations to @SimonPerrin15 for his travel award and poster presentation 芦聽Schwann cells and skeletal stem/progenitor cells in periosteum drive fibrosis and congenital pseudarthrosis of the tibia in NF1聽禄 @ASBMR @Inserm @IMRB_Mondor @UPECactus
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