I'm a neuroscientist at @AlzheimerAms and @lunduniversity specializing in neuroimaging
Joined July 2017
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The Atypical AD PIA Clinical Case Report Webinar is coming up! This webinar will feature Clinical Decision-Making in Atypical Alzheimer's Disease: Navigating Treatment in Complex Presentations and an exciting speaker line-up. Register now, here: alz-org.zoom.us/webinar/regi…
Colin Groot retweeted
So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠
🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this survey: alz.surveymonkey.com/r/923BT…
🚨Calling all neuroimagers! Help @EmmaCoomans shape the opening plenary at #AIC2025 (Toronto, July 26th) "Accomplishments of the Past Year" and share the most impactful neuroimaging research from the past year via this brief survey (~5min) by May 30th.
act.alz.org/site/R?i=eOejFv9…
Honored to have been awarded an Alzheimer Nederland Early Career grant! I will use this grant to determine Alzheimer's disease prevalences and incidence rates in a large multi-center dataset @RikOssenkoppele @alzheimernl @AlzheimerAms
Very excited to see our paper on neuroimaging to predict dementia in MCI as the Editor's Pick on the JAMA Neurology website. You can find our open access paper here: jamanetwork.com/journals/jam…
Special thanks to @OskarHansson9 @RikOssenkoppele and @JAMANeuro
Colin Groot retweeted
The BeyeOMARKER study design paper is out!
In BeyeOMARKER we will screen 700 individuals with plasma p-tau217 at an eye clinic, and further characterize 150 of them with Amyloid & Tau PET, MRI, retinal imaging and cognitive & cortical vision assessment.
Thanks to the great team at @AlzheimerAms, especially @ilse_bader, @j_milongo & @Colin__Groot.
Link to paper @AlzheimersRes (open access) > pubmed.ncbi.nlm.nih.gov/3916…
Colin Groot retweeted
Pleased to present our latest work "Tau PET for predicting dementia in individuals with MCI", led by @Colin__Groot!
Open access link @JAMANeuro > jamanetwork.com/journals/jam…
@SEMastenbroek @EStomrud @alexa_pichetb @AntoineLeuzy @SebastianPalmqv @NiklasMattsson4 @VGaribotto @AlzheimerAms @UCSFmac @biofinder_study @OskarHansson9
Colin Groot retweeted
The implications of Aβ pathology: Only time will tell
🚨 Our scientific commentary is just out in Brain!
@EmmaCoomans and I had the privilege to write an editorial on the recent publication "Characterizing brain tau and cognitive decline along the amyloid timeline in Alzheimer’s disease" @Brain1878.
Take home message:
"The modelling work conducted by Cody et al. suggests that the first decade after amyloid-β onset – before tau has reached the inferior temporal gyrus and before the most pronounced effects on cognition are observed – is a crucial time window for intervention (see Figure)."
Link to editorial > academic.oup.com/brain/advan…
Link to primary paper > academic.oup.com/brain/advan…
Colin Groot retweeted
🧠Thrilled to join the @ISTAART @AtypicalPIA Journal Club with @CorriveauNick and @DavidJonesBrain! Can't wait to dive into their groundbreaking findings. You're all invited to meet the authors and fire away with your questions! 📚 @RikOssenkoppele @Colin__Groot
Colin Groot retweeted
🗓️ 𝐋𝐮𝐧𝐜𝐡 & 𝐋𝐞𝐚𝐫𝐧 𝐰𝐞𝐛𝐢𝐧𝐚𝐫. Wil jij op de hoogte blijven van de laatste ontwikkelingen op het gebied van #dementie? Sluit aan bij de #webinar van Colin Groot over "Beschermende factoren tegen de ziekte van Alzheimer" op 24 november.👇
alzheimercentrum.nl/patiente…
Colin Groot retweeted
Onlangs publiceerde @Colin__Groot en zijn team in het wetenschappelijk tijdschrift @Brain1878. Uit het onderzoek blijkt dat het combineren van #tau-biomarkers, #klinisch onderzoek efficiënter kan maken. Lezen hoe dat kan?
👉alzheimercentrum.nl/blogarti…
A big thank you to @alzforum for covering our recent publication wherein we propose to update the AT(N) criteria to APT(N). Read all about it here: alzforum.org/news/research-n…
Colin Groot retweeted
Thanks @alzforum for the great coverage of our recent publication.
W/@Colin__Groot, @OskarHansson9
Time to update the ATN diagnostic criteria for #alzheimersdisease? Phospho-tau (P) rises in biofluids years before tau tangles (T) surpass a threshold on tau-PET scans.
@lunduniversity ow.ly/WQnl50KM6Xw
Check out our new paper on CSF p-tau+ / tau-PET- (discordant) individuals. Our findings suggest that it pays to split "T" from the AT(N) classification into a separate biofluid p-tau "P" and tau-PET "T" category.
academic.oup.com/brain/advan…
Op 26 september spreek ik tijdens de Dementie Update, georganiseerd door @Alzheimercentrum Amsterdam, Amsterdam UMC. Op het programma actuele ontwikkelingen en thema's op het gebied van patiëntenzorg en wetenschappelijk onderzoek rondom dementie. #alzheimer #dementieupdate
Colin Groot retweeted
NEW: we have a #PhD position available focusing on modeling of pathological disease progression in #Alzheimer and #FTD using (ante- and post-mortem) brain imaging and immuno histochemistry data.
@AlzheimerAms w/@NeuroLaura
Apply 👇 werkenbij.amsterdamumc.org/e… – at Amsterdam, The Netherlands
Out now in @Brain1878: "Do genetic factors contribute to sex-specific differences in resilience to Aβ pathology?" bit.ly/3HPtGdJ
@RikOssenkoppele, @HolstegeHenne
A commentary on an amazing paper: bit.ly/3QBrZVb led by @jackieeissman, @timothyjhohman
Colin Groot retweeted
Are #Amyloid and #Tau #PET positive cognitively unimpaired individuals destined to decline?
Find out in our new preprint: bit.ly/3yXRrOf.
See a thread👇1/11
Colin Groot retweeted
@Colin__Groot is gekozen als bestuurslid congrescomité Alzheimer’s Imaging Consortium (AIC). Het #AIC congres focust zich op de klinische applicatie en ontwikkeling van beeldvormende technieken die ons helpen onderzoek te doen naar alzheimer. Meer lezen? bitly.ws/roio
Colin Groot retweeted
Our new preprint: @Colin__Groot employed a #Bayesian modelling framework to detect distinct latent #atrophy factors in posterior cortical atrophy (#PCA). biorxiv.org/content/10.1101/… w/@bttyeo, @_JakeVogel_, @relajoie, @PhilipAlz, @AlzheimerAms & @UCSFmac
Bedankt @alzheimernl voor het toekennen van een fellowship beurs voor 6 maanden! Ik zal hier dankbaar gebruik van maken door in Melbourne onderzoek te gaan doen naar witte stof veranderingen en regionale verspreiding van tau in cognitieve subtypes van de ziekte van Alzheimer.