Associate Professor and Cardiologist, @UUtah @UofUHealth. Studying #mitochondria, #ionchannels, and #heartfailure. Section chief, general cardiology.
Salt Lake City, UT
Joined January 2019
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✨Excess fat makes the liver act like it's under viral attack.✨
In a new publication in @jclinicalinvest , we describe how a maladaptive antiviral stress response causes liver injury in metabolic liver disease (MASH). 1/14
Dipayan Chaudhuri retweeted
What if we could predict the course of the next pandemic before it happened? Tyler Starr, PhD, biochemist at University of Utah Health, studies viral evolution to do just that. Watch the full presentation: youtu.be/il12erThI6g?si=a_HH…
Dipayan Chaudhuri retweeted
Blocking EFHD1 protects against liver damage in #MASH models: doi.org/10.1172/JCI204023
Dipayan Chaudhuri @ChaudhuriLab & team @UUtah identify EFHD1 as a protein in liver cells that triggers a maladaptive viral response during metabolic stress. In human organoid and mouse models, blocking EFHD1 blunted hepatocyte damage.
The loss of EFHD1 in mouse liver resulted in longer, spaghetti-like mitochondria, as seen in image (1/3). The featured electron micrograph (2/3) shows a liver cell mitochondria about to undergo fission, surrounded by an extensive network of ER contacting it.
#LiverDisease
Dipayan Chaudhuri retweeted
Today, the MitoCarta Tree of Life Consortium (MitoTOL) is releasing high-accuracy mitochondrial proteomes across diverse eukaryotes to empower studies of physiology, evolution, and disease:
cell.com/consortium/mitocart…
All data can be accessed at:
mitocarta.org
Dipayan Chaudhuri retweeted
Congratulations to Dr. Sah! A well deserved honor.
The Department of Medicine is pleased to announce Dr. Rajan Sah has been appointed the Alan A. and Edith L. Wolff Endowed Professor of @WashUCardiology
Dr. Sah’s research focuses on ion channel biology, mechanosensing, and cardiometabolic disease.
> internalmedicine.wustl.edu/r…
ALT Department of Medicine Professorship Announcement
Dipayan Chaudhuri retweeted
Today at the 2026 Bioscience Symposium: CVRTI investigator Dipayan Chaudhuri (@ChaudhuriLab) will present work newly published in the Journal of Clinical Investigation (JCI).
Dr. Chaudhuri will join researchers from across the University of Utah for an afternoon of scientific presentations and discussion.
Today, September 8
11:00 AM - 7:00 PM
Cleone Peterson Eccles Alumni House
@RobinShawCVRTI
#CardiovascularResearch #BioscienceResearch #UniversityOfUtah
ALT Flyer for the University of Utah’s 2026 Bioscience Symposium & Don Summers Memorial Lectures on September 8, 2026, from 11:00 AM to 7:00 PM at the Cleone Peterson Eccles Alumni House. The afternoon program includes CVRTI investigator Dipayan Chaudhuri presenting during the Red Session, along with researchers from across University of Utah bioscience programs.
Dipayan Chaudhuri retweeted
This is a really great paper, and a wonderful example of how we can use human genetics to guide us to mechanisms that are relevant to physiology and pathology in humans.
✨Excess fat makes the liver act like it's under viral attack.✨
In a new publication in @jclinicalinvest , we describe how a maladaptive antiviral stress response causes liver injury in metabolic liver disease (MASH). 1/14
Dipayan Chaudhuri retweeted
Amazing work from the Chaudhuri lab linking altered ER-mitochondria interactions with calcium signaling and antiviral responses in the context of MASH! Congratulations to the team!
✨Excess fat makes the liver act like it's under viral attack.✨
In a new publication in @jclinicalinvest , we describe how a maladaptive antiviral stress response causes liver injury in metabolic liver disease (MASH). 1/14
Dipayan Chaudhuri retweeted
Excited to see this work published in The Journal of Clinical Investigation! A highly collaborative study uncovering a new mechanism driving liver injury in MASH. Glad to have contributed!
Congratulations to David, Dipayan, and the entire team!
✨Excess fat makes the liver act like it's under viral attack.✨
In a new publication in @jclinicalinvest , we describe how a maladaptive antiviral stress response causes liver injury in metabolic liver disease (MASH). 1/14
Dipayan Chaudhuri retweeted
Nothing scares me more than Spontaneous Coronary Artery Dissection (#SCAD), a leading cause of heart attacks in younger women. Yet much of its underlying biology has remained elusive—until now. This study in @CircAHA, led my colleagues at @CVPath_Md, will be a landmark study for 2 reasons: 1) for the first time, a potentially universal structural defect was found in all SCAD cases examined - a reduced medial collagen & smooth muscle cell changes, pointing to a fundamental arterial wall weakness. 2) in quarter of cases, we found pathogenic extracellular matrix variants, correlating with severe, multivessel dissections. @michiganstateu, @MSUMD , @MSU_Medicine, Tagging national #SCAD expert @EstherSHKimMD! ahajournals.org/doi/10.1161/…
This was led by @DavidEber1991 . Thanks to @RobinShawCVRTI, @MimcheLab , @BoudinaSihem , @StavrosDrakos , @AdemuyiwaAromo1 , @SarahMarsing , Vivek Garg, Will Holland, @ScottSummers339, @MarcusPezzolesi , Jared Rutter, Kim Evason, @InSphero , @thermofisher and their groups. 13/14