The Cancer Dependency Map retweeted
In a new study, researchers from @MGHCancerCenter and colleagues' 'cell line atlas' provides a crucial resource for developing therapies for biliary tract cancer. The study was published in @CD_AACR.
Read more: massgeneralbrigham.org/en/ab… @getz_lab @DrFranVazquez
doi.org/10.1158/2159-8290.CD…
The Cancer Dependency Map retweeted
A new cell line atlas of biliary tract cancers uncovers new subtypes and potential drug targets for better treatment of these deadly diseases. Learn more: broad.io/DepMap-BTCs
@MGBResearchNews @targetcancer
The Cancer Dependency Map retweeted
theprismlab.org/white-papers…
@CancerDepMap - PRISM screens can work with ADCs, bystander effects non-withstanding.
The Cancer Dependency Map retweeted
🚨Exciting New Synthetic Lethal Target from #depmap!
Scientists have discovered a genetic vulnerability — found in 5 percent of adult cancers — that could be a promising drug target. broad.io/PELO-News
ALT illustration of genes being "targeted" with darts
The Cancer Dependency Map retweeted
📢 Registration is now open for an exciting Gordon Conference on synthetic lethality organized by Ben Schwartz (GSK), Mathew Garnett (Sanger), and Francisca Vazquez (DepMap Director, Broad Institute)
Highly recommended!
Register here
grc.org/synthetic-lethality-…
The Cancer Dependency Map retweeted
DepMap keeps growing—and so does the portal!
To help navigate the portal, new in 24Q4 we’ve launched a new resource page 🚀! Check it out and share your feedback.
depmap.org/portal/resources
The Cancer Dependency Map retweeted
New DepMap Release!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org)
⭐ First 281 WES -> WGS
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1)
Read our release notes for more info!
The Cancer Dependency Map retweeted
NEW content online! The present and future of the Cancer Dependency Map go.nature.com/4fiZ6sw
The Cancer Dependency Map retweeted
We identified PHF6 as a critical #dependency for the survival of #SMARCB1-mutant cancers through #CRISPR screenings conducted in collaboration with @cancerdepmap.
The Cancer Dependency Map retweeted
New data is live on depmap.org! We are excited to share new CRISPR and omics data, an update in our CRISPR method, Chronos and a new portal interface. #DepMapPortal #DepMap #OpenScience #CancerResearch
The Cancer Dependency Map retweeted
Wrong tag here.
I meant to highlight the fantastic resources available on @CancerDepMap that we used to cross-validate the gene hits from our siRNA screen to ensure these were true core vulnerabilities in GBM.
So grateful to the scientists who made these datasets available 🙏
To prioritize targets, we cross-evaluated our siRNA screening results with the CRISPR loss-of-function screen dataset from the Cancer Dependency Map Project (@Depmap ou @BroadInstitute) and confirmed 9 targetable core vulnerabilities.
6/n
The Cancer Dependency Map retweeted
It took a while but here it is! Excited to share our latest work led by Xiao Chen and Yinglu Li on the interplay between PRC2 and MLL-MEN1 complex in lymphoid cancers identified through genetic co-dependency mapping.
nature.com/articles/s41467-0…
The Cancer Dependency Map retweeted
The 23Q2 data release is live on depmap.org! We are excited to share new CRISPR and omics data, an update in our CRISPR method, Chronos, a new Target Discovery app and a new cell line page. #DepMapPortal #DepMap #OpenScience #CancerResearch
The Cancer Dependency Map retweeted
From the March issue of Cancer Discovery—
A #Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas, by @lisacervia, Tsukasa Shibue, @DrFranVazquez, Bill Hahn et al.
bit.ly/3z9hwc3
@broadinstitute @DanaFarber @CancerDepMap #openaccess
The Cancer Dependency Map retweeted
Finally I want also to thank @CancerDepMap for all their brilliant work and making all the data available for the scientific community ✅ and encourage all the cancer researchers to explore the data from the portal!
The Cancer Dependency Map retweeted
Genetic dependencies associated with transcription factor activities in human cancer cell lines - new work from our @Boehringer PostDoc @itsvenu_ integrating @CancerDepMap and #TCGA data #CancerTargets #GCBDS
biorxiv.org/content/10.1101/…
The Cancer Dependency Map retweeted
We’re excited to be partnering with the @broadinstitute alongside other organizations on the @CancerDepMap Project. We hope this will help us discover new tumor vulnerabilities that one day could lead to cures for patients. #syntheticlethal #depmap #cancerresearch
Broad's @CancerDepMap Consortium, is entering a new phase, with 19 biopharma partners, and accelerating its research into tumor vulnerabilities and identifying key biomarkers. broad.io/DepMap-News-011823
The Cancer Dependency Map retweeted
Broad's @CancerDepMap Consortium, is entering a new phase, with 19 biopharma partners, and accelerating its research into tumor vulnerabilities and identifying key biomarkers. broad.io/DepMap-News-011823
The Cancer Dependency Map retweeted
A #Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas, by @lisacervia, Tsukasa Shibue, @DrFranVazquez, Bill Hahn et al.
bit.ly/3jQjyJF
@broadinstitute @DanaFarber @CancerDepMap
