@TheRobertsLab1
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The lab of Charlie Roberts at @stjuderesearch studying SWI/SNF chromatin remodeling complex. Tweets are from lab members unless signed CR.
Joined August 2019
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Delighted to have contributed to this work from the impressive lab of Dr. Ben Garcia! sciencedirect.com/science/ar…
Excited to share our latest study in @NatureComms where we uncover a new mechanism of chromatin regulation that is essential in certain SWI/SNF-mutant cancers. Congrats to @HaydenMalone3 and coauthors! #SWISNF #cancer (1/8)
@stjuderesearch @stjudegraduate
nature.com/articles/s41467-0…
Finally, we show that PHIP inactivation significantly extends survival in vivo using patient-derived orthotopic xenograft models of pediatric #rhabdoidtumors, underscoring its potential as a therapeutic target. #PediatricCancer #ATRT (7/8)
Thank you to all of our coauthors, collaborators, lab members, and funding sources (@StJude @stjudegraduate @NIHfunding @theNCI @CureATRTNow @PedDep) for supporting this work. (8/8)
The Roberts lab is seeking candidates with an interest in #chromatinbiology for a Researcher position. Check out the details below to apply! talent.stjude.org/careers/Jo…
Trainees Rebekah Eleazer, Sara Kassel, and Jordan Skorupa representing the Roberts lab at Cold Spring Harbor Laboratory's Mechanisms of Eukaryotic Transcription course this week!🧬
The Roberts Lab is looking for highly motivated, intellectually engaged candidates with an interest in #ChromatinBiology to fill a Researcher position. Check out the link below and feel free to reach out with any inquiries! talent.stjude.org/careers/jo…
Fascinating new @CellReports paper from @HainerLab directly comparing the effects of all SNF2 family chromatin remodelers upon transcription of mRNAs, eRNAs, and uaRNAs in ES cells.
sciencedirect.com/science/ar…
The Roberts Lab retweeted
Cuts in NIH research grants will have a lasting negative impact on science and medicine in the U.S. Grants will continue to fund specific research costs, but essential infrastructure like labs, advanced equipment and support staff are crucial for groundbreaking work.
The Roberts Lab is looking for highly motivated, intellectually engaged candidates with an interest in #ChromatinBiology to fill a Researcher position. Check out the link below and feel free to reach out with any inquiries! talent.stjude.org/careers/jo…
We are excited to have Kirill Miachin, an MD,PhD student from @GarciaLabMS's lab train with us for the next two weeks. Welcome aboard, Kirill!
Check out this fantastic Research Highlight covering our recent work with @HongYue88665668 @fischerlab1 on DCAF5 published in @Nature. Original Tweetorial linked below!
nature.com/articles/s41392-0…
We are delighted to see our Review featured on the cover of the September issue of @NatRevDrugDisc. Original tweetatorial is linked below! @HaydenMalone3 @StJudeResearch @stjudegraduate
Our September issue is live! Read about muscarinic receptor modulators for schizophrenia, chromatin remodellers as therapeutic targets, lipid nanoparticles for nucleic acid delivery, new epilepsy therapies in development and more here nature.com/nrd/volumes/23/is…
Excited to share our new review in @NatRevDrugDisc covering ongoing efforts to therapeutically target chromatin remodelers focusing on SWI/SNF complexes. Congratulations to authors @HaydenMalone3 and Charlie! @stjudegraduate @stjuderesearch #swisnf (1/9) nature.com/articles/s41573-0…
