Senior Director of Proteomics & Group Leader @Genentech. Passion for developing proteomics technologies that fuel therapeutic discovery. Tweets are mine.
Bay Area, CA
Joined June 2016
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For those looking for a new proteomics opportunity, there is a position open within the Translational Medicine group. This is a fantastic opportunity to perform impactful research using cutting edge technology. Check it out below!
careers.gene.com/us/en/job/2…
Very excited to see work from Hanna Budayeva included in this special issue of @JProteomeRes. Hanna has done a fantastic job leading our chemoproteomics efforts over the last few years - this story is just one of the exciting things her group is working on! Check out this issue!
The latest issue of Journal of Proteome Research is live! On the cover: "Celebrating Women in Proteomics and Metabolomics"
Read it here: pubs.acs.org/doi/full/10.102…
Great work out of @susanklaeger’s lab. Denys was a fantastic intern. He not only spearheaded this project, but also helped with optimization of DIA methods for our timsTOF. Thanks @fmeierX for being supportive of his time with us! Check out the paper, some great findings there!
Very nice to see the result of my internship at @genentech out in @biorxivpreprint! If you’re intersted in diaPASEF and immunopeptidomics, check this out:
biorxiv.org/content/10.1101/…. Big thanks to @susanklaeger and @CMichaelRose for introducing me to immunopeptidomics!
Our Proteomic and Genomic Technologies department has 14 presentations across oral & poster sessions and breakfast & evening workshops at #ASMS2024. Very grateful to work with many talented researchers & very excited to share our research next-door to the happiest place on earth!
Very excited to see Ying’s work recognized @us_hupo, couldn’t be there to celebrate but very excited to have Ying as part of our department @genentech.
Very much enjoyed the wonderful @us_hupo and received the Robert Cotter award. So thankful to the community for the recognition and the opportunity to share my journal to proteomics
Anyone looking for a Postdoc should check out @dschweppe1 lab. Very exciting work happening there and he would be a great mentor!
#TeamMassSpec We're recruiting postdocs to work on new methods to map proteome remodeling due to chemical perturbations, aging, development, and more! If you're interested, see the job posting:
ap.washington.edu/ahr/positi…
and some of the lab's projects: schweppelab.org/projects
Excited to see that our paper is getting some views! If you haven’t checked it out yet, take a look! We have also been testing this approach with single cell samples and are aiming to get another short note together around those data. Stay tuned!
🔓 #OpenAccess + Most Read in the past 30 days: "Increasing the Throughput and Reproducibility of Activity-Based Proteome Profiling Studies with Hyperplexing and Intelligent Data Acquisition"
go.acs.org/87N
Christopher Rose retweeted
Interested in learning more about immunopeptidomics? Join us this summer in Montreal for the 3rd HUPO-HIPP summer school:
Save the date! The 3rd HUPO-HIPP summer school. Université de Montréal, Canada August 14th to 16th 2024. @hupo_org #immunopeptidomics #HLA hupo-hipp-summer-school.mail…
Looks like this deadline got pushed out…that is great for folks who wanted to submit but weren’t going to make the previous deadline. I might be in that group 👀.
❗ We still welcome submissions for a 2024 Special Issue on Single-Cell Omics Research, managed by @slavov_n & @thalexandrov. Deadline to submit is 7/31/24 ➡️ go.acs.org/7Te
Two of my favorite things are Disneyland and Proteomics. I have been looking forward to ASMS in Anaheim for years. Hopefully I will see you all there, I will be around but a little preoccupied with a new family addition arriving in March. Excited for baby’s first Disneyland trip!
Thanks, Asher, for reminding people to register for the 2024 @asmsnews conference and a chance to purchase discount tickets to visit Mickey’s house. asms.org/conferences/annual-…
Christopher Rose retweeted
Tune in to this week's #TheProteomicsShow ! Dr. Ying Zhu, Genentech Inc., joins us to dive deep into the groundbreaking nanoPOTS technology, reshaping single-cell proteomics. Listen here: bit.ly/48rhawZ
Introducing "The Oregon Trail" by #TheProteomicsShow! Join us for a glimpse into the 20th-anniversary conference in Portland, OR. Don't miss Dr. Lisa Jones from UC San Diego in our debut episode, who will be part of the session "Serendipity in Proteomics." bit.ly/46GO77A
Fantastic work - check it out!
In our latest pre-print, we studied how protein post-translational modifications (PTMs) change during brain aging. Kudos to the incredible team at @AOri_lab @AntonioMarinoMB @DomenicoFraia @panfilovadi @AmitKusahu1598 biorxiv.org/content/10.1101/…
Christopher Rose retweeted
Systematic discovery of neoepitope–HLA pairs for neoantigens shared among patients and tumor types - @genentech @AdaptiveBiotech go.nature.com/3M3zoMf
Excited to share the publication of a large collaborative effort @genentech to discover shared cancer neoantigen neoepitopes. From 47 cancer neoantigens and 15 HLA alleles we discovered 86 neoepitope-HLA pairs, 65 were novel at acceptance - check it out! nature.com/articles/s41587-0…
FLT3D835Y/A*02:01 was novel at acceptance, but then described 2 weeks ago in @NatureCancer. We also found TCRs against this neoantigen, but this manuscript beautifully demonstrates in vivo activity vs patient derived AML cells. Check this one out too! nature.com/articles/s43018-0…
Christopher Rose retweeted
10 years ago, our own Ira Mellman helped develop a framework called the Cancer-Immunity Cycle. Recently, he, Shannon Turley, and others reviewed advancements made in the field since then and looked ahead to the next generation of cancer immunotherapy treatments. Read more⬇️
The #cancerimmunitycycle provides a framework to understand the events that generate anti-cancer immune responses. Mellman, Chen, Powles, and Turley consider the last 10 years of research in cancer immunology and immunotherapy & review the progress in understanding each step of the cancer-immunity cycle, identifying challenges and opportunities for the next decade. authors.elsevier.com/a/1huvh…
As you head to @hupo_org, why not read our new article? Hanna Budayeva demonstrates increased throughput of cysteine profiling with hyperplexing. I also add an intelligent data acquisition method, PairQuant, that drastically improves data completeness. biorxiv.org/content/10.1101/…
Very interesting that hyperplexing is being discussed in three different talks during the @thermofisher TMT Symposium. Check out my talk starting in a few mins on our PairQuant approach to hyperplexing acquisition, will hopefully be of interest.