Neural Repair Laboratory at the Department of Neurosurgery, University of Pennsylvania
Philadelphia, PA
Joined June 2022
- Tweets19
- Following23
- Followers113
- Likes4
BrainRepairLab (Dr. Isaac Chen Lab) retweeted
Now out in @Nature, @sun_yusha, @XinW_up, and additional members of the @UPenn_SongMing, @BrainRepairLab, and @DrORourke2 labs introduced trans-synaptic tracing tools from circuit neuroscience to study the whole-brain connectome of glioblastoma.
➡️ spr.ly/6011a7Fqc
A big congratulations to our lab member and medical student researcher, Shikha Singh, for an acceptance into the Master of Science in Translational Research (MSTR) program at the University of Pennsylvania.
Keep a look out for her great work!
Our latest paper highlights the most recent progress and remaining challenges in using cell replacement therapy for the treatment of Parkinson’s Disease and Cortical Injury
Check it out here:
mdpi.com/2076-3425/13/12/165…
@PennNSG @PennMedicine @DennisJgamadze
BrainRepairLab (Dr. Isaac Chen Lab) retweeted
For a new publication in @NatureComms, @StevenBremMD, @dhpri, @WolfLabPenn, and @BrainRepairLab contributed to a study titled, "CHEX-seq detects single-cell genomic single-stranded DNA with catalytical potential."
➡️ spr.ly/6011uItOH
The Chen Lab at @SfNtweets! Incredible talks this weekend.
Check out Adam Sjoholm’s poster tomorrow 8am-12 (Y18) titled “Novel visual detection task to measure behavioral deficits in rats following TBI”
@PennNSG
Lab members left to right: Adam Sjoholm, Mackenzie Castellanos, @DennisJgamadze, @hamimi_01, Jaeha Kim
BrainRepairLab (Dr. Isaac Chen Lab) retweeted
For @CurrentBiology, Isaac Chen, MD contributed to a paper where it was learned that odor representations from nostrils are segregated in the piriform cortex, showing an olfactory coding scheme that parses info across nostrils in a single inhalation.
➡️ spr.ly/6014uqMBn
Thank you so much to @CellStemCell for highlighting our paper and including it in their stand-out stem cell research list!!
Check the paper out here: cell.com/cell-stem-cell/full…
@PennNSG
Read a selection of editors top picks
hubs.ly/Q026wV_-0
Join the @CellStemCell author community
Affiliated with @ISSCR
This month’s lab dinner was all about celebrating @DennisJgamadze’s new position as Research Assistant Professor of Neurosurgery.
Congrats Dennis, so well deserved!!
@PennNSG
Congratulations to our undergraduate researcher, Nitin Seshadri '25 for receiving the UPenn CURF Research Grant to conduct research on the “Effect of Traumatic Brain Injury on Visual Stimulus Reaction Time".
Check out the latest podcast from <The One’s Changing the World> featuring Dr. Isaac Chen. In the podcast, Dr. Chen goes through research conducted in the ChenLab regarding “organoid implantation in rats” and how such research could aid treatment of neurological disorders.
BrainRepairLab (Dr. Isaac Chen Lab) retweeted
Human brain ‘organoids’ grafted into rats take note of light and pattern go.nature.com/3HZFg7T
BrainRepairLab (Dr. Isaac Chen Lab) retweeted
The latest advance in brain organoids. Human neural implants are surprisingly good at integrating with host brains in adult rats. @Penn research could pave the way to treating brain injuries with organoid grafts ft.com/content/d8672e07-2276…
BrainRepairLab (Dr. Isaac Chen Lab) retweeted
When transplanted into injured adult rat brains, human brain organoids can grow, send out neural signals, and respond to visual stimuli.
@PennMedicine
Read more in @CellStemCell
cell.com/cell-stem-cell/full…
Our team has just published a new paper : authors.elsevier.com/c/1gX1h… in @CellStemCell on the integration of human forebrain organoids with the injured adult rat visual system. Congrats to @DennisJgamadze and the team on this big step! @CellPressNews. Highlights of the study👇🧵
* Organoids transplanted into an injury cavity integrate with adult rat visual system.
* We found a polysynaptic pathway between organoid neurons and host retina.
* Visual stimulation of host animals showed orientation selectivity in organoids.