Terrible case of "esprit de l'escalier" (this is a thing, Google it).
In the coach, back from defending my proposal in front of the panel,
and thinking of aaaaall the perfectly good answers to their questions.
Missed them all, pretty much. 😣
🚨New preprint Alert🚨
Shared Structural Features of Miro Binding Control Mitochondrial Homeostasis biorxiv.org/content/10.1101/…
If you want to get the gist follow the 🧵
This will spark more research!
The hydrophobic pocket is part of a Ca++ binding domain. What's the crosstalk?
We now can surgically disrupt client-Miro interaction without affecting other functions of client or Miro. What's the significance?
just stumbled upon a @eLife paper. Title seemed awesome but out of my field. couldn't know if it was a paper I needed to read ASAP or if it could wait.
I just read the eLife assessment and
got much more info than just knowing the journal name.
Get into the habit of doing that!
Great talk by Ben Barres Spotlight awardee @AJKowaltowski !
With seminars like this, science has no problem reaching all corners of the globe. Journals' purpose isn't dissemination anymore, but evaluation.
Time to endorse this and change the way we publish. @eLife
Thank you to @AJKowaltowski for the great lecture, to @BenoitKornmann for the discussion on the new @eLife model, and to the 250+ participants!
See you again next month, for another @MITOtalk!
Undisclosed conflict of interest
(why am I even trying to imitate the inimitable @OdedRechavi ?)
Not very active on twitter anymore but THIS deserves a shoutout 🤯
nature.com/articles/s41586-0…
Benoît Kornmann retweeted
#NatMetabPicks | In @NatureCellBio, the team led by @BenoitKornmann (@UniofOxford, @StHughsCollege) develop METALIC, a tool to track interorganelle #lipid flux in live cells using organelle-targeted enzymatic labeling of lipid subpopulations & mass spec.
nature.com/articles/s41556-0…
Benoît Kornmann retweeted
NEW ONLINE: @KornmannLab @ATJohnPeter and colleagues develop METALIC, an approach to track interorganelle lipid flux in live cells.
PDF: rdcu.be/cPxpQ
nature.com/articles/s41556-0…
Thanks James!
This is so cool!! METALIC (Mass tagging-Enabled TrAcking of Lipids In Cells), a method to track interorganelle lipid flux inside cells, is used to study ERMES and Vps13 lipid transport function. Amazing @ATJohnPeter @BenoitKornmann! 🤩🔥👏 nature.com/articles/s41556-0…
Our paper is out in @NatureCellBio
We present a new method to measure intracellular lipid trafficking in vivo and decipher the contributions of ERMES and Vps13-Mcp1 complexes in mitochondrial lipid supply.
nature.com/articles/s41556-0…






